Channel:  The Howard Hughes Medical Institute (HHMI)

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Striatal neural ensemble codes for voluntary locomotor and involuntary dyskinetic movements
Chattree, G., Chrapkiewicz, R., Zhang, Y., Li, J., Schnitzer, M. J.
10.1101/2025.04.01.646527 — Posted: 2025-04-02
The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture
Navarro, P. P., Vettiger, A., Hajdu, R., Ananda, V. Y., Lopez-Tavares, A., Schmid, E., Walter, J., Loose, M., Chao, L. H., Bernhardt, T. G.
10.1101/2025.04.02.646830 — Posted: 2025-04-02
A miniature CRISPR-Cas10 enzyme confers immunity by an inverse signaling pathway
Doherty, E. E., Adler, B. A., Yoon, P. H., Hsieh, K., Loi, K., Armbruster, E. G., Lahiri, A., Bolling, C. S., Wilcox, X. E., Akkati, A., Iavarone, A. T., Pogliano, J., Doudna, J. A.
10.1101/2025.03.28.646030 — Posted: 2025-04-01
NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT
Wu, Z., Nguyen, P. T., Sondhi, V., Yao, R.-W., Dai, T., Chiang, J.-C., Shang, Z., Cai, F., Zhang, J., Moore, M. D., Alshamleh, I., Li, X., Ogu, T., Zacharias, L. G., Winston, R., Patricio, J. S., Johnson, X., Chen, W.-M., Cong, Q., Mathews, T. P., Zhang, Y., DeBerardinis, R. J.
10.1101/2025.03.29.646096 — Posted: 2025-04-01
SIRT2 Mediates Integrated Stress Response by Deacetylating and Stabilizing 4EBP1 to Suppress Translation
Zi, Y., Wang, M., Hou, D., Cerione, R. A., Lin, H.
10.1101/2025.03.31.646365 — Posted: 2025-04-01
Mechanistic insights into direct DNA and RNA strand transfer and dynamic protein exchange of SSB and RPA
Paul, T., Lee, I.-R., Pangeni, S., Rashid, F., Yang, O., Antony, E., Berger, J. M., Myong, S., Ha, T.
10.1101/2025.04.01.643995 — Posted: 2025-04-01
In-Situ High-Resolution Cryo-EM Reconstructions from CEMOVIS
Elferich, J., Kaminek, M., Kong, L., Odriozola, A., Kukulski, W., Zuber, B., Grigorieff, N.
10.1101/2025.03.29.646093 — Posted: 2025-03-31
Glutamate indicators with increased sensitivity and tailored deactivation rates
Aggarwal, A., Negrean, A., Chen, Y., Iyer, R., Reep, D., Liu, A., Palutla, A., Xie, M. E., MacLennan, B., Hagihara, K. M., Kinsey, L. W., Sun, J. L., Yao, P., Zheng, J., Tsang, A., Tsegaye, G., Zhang, Y., Patel, R. H., Arthur, B. J., Hiblot, J., Leippe, P., Tarnawski, M., Marvin, J. S., Vevea, J. D., Turaga, S. C., Tebo, A. G., Carandini, M., Rossi, L. F., Kleinfeld, D., Konnerth, A., Svoboda, K., Turner, G. C., Hasseman, J., Podgorski, K.
10.1101/2025.03.20.643984 — Posted: 2025-03-31
IL-25-induced memory ILC2s mediate long-term small intestinal adaptation
Cortez, V. S., Viragova, S., Koga, S., Liu, M., O'Leary, C., Ricardo-Gonzalez, R. R., Schroeder, A. W., Kochhar, N., Klein, O., Diamond, M., Liang, H.-E., Locksley, R. M.
10.1101/2025.03.25.645270 — Posted: 2025-03-29
Interleukin-1 receptor antagonist is a conserved early factor for exacerbating tuberculosis susceptibility
Lee, O. V., Ji, D. X., Rosa, B. A., Jaye, D. L., Suliman, S., Mitreva, M., Gabay, C., Vance, R. E., Kotov, D. I.
10.1101/2023.10.27.564420 — Posted: 2025-03-29

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