Channel:  The Howard Hughes Medical Institute (HHMI)

2,398 Articles

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Chromatix: a differentiable, GPU-accelerated wave-optics library
Deb, D., Both, G.-J., Bezzam, E., Kohli, A., Yang, S., Chaware, A., Allier, C., Cai, C., Anderberg, G., Eybposh, M. H., Schneider, M. C., Heintzmann, R., Rivera-Sanchez, F. A., Simmerer, C., Meng, G., Tormes-Vaquerano, J., Han, S., Shanmugavel, S. C., Maruvada, T., Yang, X., Kim, Y., Diederich, B., Joo, C., Waller, L., Durr, N. J., Pegard, N. C., La Riviere, P. J., Horstmeyer, R., Chowdhury, S., Turaga, S. C.
10.1101/2025.04.29.651152 — Posted: 2026-03-25
Homozygosity for rare or common hypomorphic IL23R variants confers a predisposition to tuberculosis in humans
Olguin Calderon, D., Kilpatrick, L. E., Conil, C., Philippot, Q., Ogishi, M., Vellutini, J., Eun Han, J., Keating, N., Li, H., Rao, G., Bohlen, J., Lay, C. S., Platt, S., Kerner, G., Feredj, E., Peel, J., Momenilandi, M., Seeleuthner, Y., Laine, C., soudee, c., Leloup, C., Debuisson, C., Lanternier, F., Bitoun, S. B., Pavy, S., Mariette, X., Rafik, A., Skhoun, H., EL Ouazzani, H., Abderahmani-Ghorfi, I., EL Baghdadi, J., Baena, A., Tejada-Giraldo, M., Barrera, L. F., Arias, A. A., Fabio, G., Carrabba, M., Emiroglu, M., Bezrodnik, L., EL Zein, L., Hammoud, H., Gregersen, P., Terrier, B., Leon L
10.64898/2026.03.23.713554 — Posted: 2026-03-25
Discovery of a primed endothelial progenitor that requires VEGF/ERK inhibition to complete vein differentiation
Ang, L. T., Zheng, S. L., Liu, K. J., Masaltseva, A., Winters, J., Jha, S. K., Yin, Q., Qian, C., Xiong, X., Dailamy, A., Xi, E., Alcocer, J. C., Sorensen, D. W., She, R., Smolyar, K., Szumska, D., Nornes, S., Martin, R. M., Lesch, B. J., Restrepo, N. K., Sun, W., Weissman, J. S., Lickert, H., Porteus, M. H., Skylar-Scott, M. A., Mosimann, C., Sumanas, S., De Val, S., Red-Horse, K., Loh, K. M.
10.1101/2025.10.11.681838 — Posted: 2026-03-25
Subsistence transition preceded population turnover in the eastern Colombian Andes
Sirak, K., Delgado, M., Triana, A., Rivas, S., Argüello, P., Boada, A. M., Rivera-Sandoval, J., Pena, G., Langebaek, C., Ospina, J. P., Archila, S., Torres Orjuela, S. A., Mejia Cano, M. B., Rodriguez Saza, F., Barton, A., Callan, K., Curtis, E., Frost, T., Iliev, L., Kearns, A., Kellogg, J., Lawson, A. M., Qiu, L., Workman, J. N., Mah, M., Nawaz, M., Soos, G., Cherkinsky, A., Hadden, C. S., Prufer, K. M., Mallick, S., Rohland, N., Fehren-Schmitz, L., Reich, D.
10.64898/2026.03.23.713713 — Posted: 2026-03-25
Bacteriophages target membrane-anchored glycopolymers to promote host cell lysis and progeny release
McKitterick, A. C., Lyerly, E. W., Bernhardt, T. G.
10.1101/2025.06.24.661397 — Posted: 2026-03-25
Progressive hypothalamic neuroinflammation after ovariectomy in mice parallels age-related transcriptomic changes in the female human hypothalamus
Bloom, J. C. B., Torres, E., Pereira, S. A., Arvizu-Sanchez, L., Fontes, A. N., Joffe, H., Page, D. C., Navarro, V. M.
10.1101/2024.10.05.616758 — Posted: 2026-03-25
Paleogenomic Evidence for Genetic Heterogeneity and Prior Admixture in Gothic-Associated Communities of Late Antique Bulgaria
Stamov, S., Chobanov, T., Wang, T., Stoeva, K., Momchilov, D., Aladzhov, A., Chobanov, K., Nikolov, M., Nesheva, D., Heather, P., Toncheva, D. I., Zamfirov, M., Lazaridis, I., Reich, D. E., Klasnakov, M., Stamov, G.
10.64898/2026.03.03.709317 — Posted: 2026-03-25
FoTO1 orchestrates Taxol biosynthesis through catalytic and non-catalytic mechanisms
Wick, C., Somani, A., Liu, J., Karunadasa, S. S., Xu, S.-L., Fordyce, P. M., McClune, C. J., Sattely, E.
10.64898/2026.03.21.713420 — Posted: 2026-03-24
Transcriptomic and functional characterization indicate sexual dimorphism of discrete circadian neuron subtypes
Perez Torres, M., Jiang, R., Ma, D., Herndon, N., Kurmangaliyev, Y. Z., Guo, F., Rosbash, M.
10.64898/2025.12.26.696620 — Posted: 2026-03-23
Inter-individual variation of cellular and gene-expression properties of the human striatum
Burger, S., Yoo, O., Nemesh, J., Muratoglu, E., Vanderburg, C., Yuan, J., Shakir, K., Mello, C. J., Rayan, N. A., Milidantri, J., Kim, K., Drouin, S., Finn, E., Gao, H., Budnik, N., Goldman, M., Fritch, H., Genovese, G., Hogan, M., Catalini, O., Kashin, S., Rockweiler, N., Wysoker, A., Macaisa, L., Reese, L., Flowers, K., Kraft, A. W., Fleming, S. J., Coe, M., Gunaratne, R., Spina, L., Crombie, C., Mohsin, A., Kamitaki, N., Macosko, E. Z., Ichihara, K., McCarroll, S. A.
10.64898/2026.03.20.713160 — Posted: 2026-03-23

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