Channel:  The Howard Hughes Medical Institute (HHMI)

2,708 Articles

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Molecular basis of ubiquitin-independent recognition and degradation of ODC/Antizyme by the 26S proteasome
Martin, A., Ramos-Ortiz, D. R., Hsieh, H.-H., Dong, K. C.
10.64898/2026.07.19.739413 — Posted: 2026-07-20
Genome-wide chromatin recording resolves dynamic cell state changes
Takei, Y., Lay, J. A., Linton, J. M., Chadly, D. M., Ochiai, Y., Hadas, R., Perez, A. A., Blanco, M. R., Laurino, P., Guttman, M., Elowitz, M. B.
10.1101/2025.08.05.668773 — Posted: 2026-07-19
Stepwise DNA unwinding gates TnpB genome-editing activity
Zhou, Z., Saffarian-Deemyad, I., Shi, H., Weiss, T., ur-Rehman, M. M., Vohra, K., Skopintsev, P., Yoon, P. H., Trinidad, M. I., Langeberg, C. J., Kamalu, M., Amerasekera, J., Zhou, Y., Doherty, E. E., Aris, K. D. P., Al-Sayyad, N., Thornton, B. W., Weissman, R. F., Wasko, K. M., Esain-Garcia, I., DeTurk, E. C., Savage, D. F., Jacobsen, S. E., Bryant, Z., Doudna, J. A.
10.64898/2026.01.09.698545 — Posted: 2026-07-18
Human vault RNAs exhibit diverse expression patterns and inter-locus compensation
Hemphill, W. O., Zaug, A. J., Hecht, C. J. S., Cech, T. R.
10.64898/2026.06.17.732918 — Posted: 2026-07-18
Integrated Interactomics Reveals Novel Protein Associations: The FOXA1-PBX1 Complex as a Case Study
Chen, Z., Szepesi-Nagy, I., Zhang, Q., Kittane, S., Gao, Y., Ortiz-Pacheco, J., Lane, E., Hatcher, J., Estrada, J., Askenazi, M., Huang, L., Ueberheide, B., Zheng, N., Toska, E., Rona, G., Pagano, M.
10.64898/2026.07.16.738938 — Posted: 2026-07-17
Nanopore-based profiling of PEGylation in nucleic acid therapeutics
Patino Guillen, G., Schmidt, T. T., Baumberg, J. J., Szostak, J. W., Keyser, U. F., Boskovic, F.
10.64898/2025.12.15.694309 — Posted: 2026-07-17
Whole-body single-cell atlas of an adult vertebrate in homeostasis and regeneration
Atabay, K. D., Aoude, P., Park, C., Kadobianskyi, M., Paugois, O. H., Judkewitz, B., Reddien, P.
10.64898/2026.02.03.703562 — Posted: 2026-07-17
Bravo! A Mosquito Antiviral Protein that Restricts Arboviruses through an RRM3-Dependent Nuclear Mechanism
Walsh, E., St Clair, L. A., Ruckert, C.
10.64898/2026.07.16.739008 — Posted: 2026-07-17
Human GPR174 deficiency drives polyclonal lymphoproliferative disease via defects in T cell function
Huang, Y.-H., Arana, K., Rachimi, S., Tam, H., Spegarova, J. S., Engelhardt, K. R., Griffin, H., Mee, M., Miano, M., Raggi, F., Grossi, A., Rusmini, M., Ceccherini, I., Dell'Orso, G., Ferro, J., Giarratana, M. C., Pillai, V., Banka, S., Garcez, T., Briggs, T. A., Mellouli, F., von Hardenberg, S., Beier, R., Auber, B., Baumann, U., Tawamie, H., Behrens, E., Oldridge, D. A., Cabrera, E. C., Xu, Y., Ouyang, S., Hambleton, S., Romberg, N., Cyster, J. G.
10.64898/2026.07.14.26357774 — Posted: 2026-07-17
Nextstrain automates real-time phylogenetic analysis of open data for endemic and emerging pathogens
Andrews, K. R., Chang, J., Roemer, C., Hadfield, J., Lin, V., Brito, A. F., Daodu, R., Joia, I. A., Kistler, K., Li, A. W., Moncla, L. H., Paredes, M. I., Kuhnert, D., Torres, L. M., Voitl, L., Aksamentov, I., Hodcroft, E. B., Huddleston, J., McCrone, J. T., Anderson, J. S., Sibley, T. R., Lee, J., Neher, R. A., Bedford, T.
10.64898/2026.03.23.713807 — Posted: 2026-07-17

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