Channel:  The Howard Hughes Medical Institute (HHMI)

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Transcriptomic and functional characterization indicate sexual dimorphism of discrete circadian neuron subtypes
Perez Torres, M., Jiang, R., Ma, D., Herndon, N., Kurmangaliyev, Y. Z., Guo, F., Rosbash, M.
10.64898/2025.12.26.696620 — Posted: 2026-03-23
Faf1 accelerates p97-mediated protein unfolding by promoting ubiquitin engagement
Liao, Z., Arkinson, C., Martin, A.
10.1101/2025.10.27.684972 — Posted: 2026-03-19
Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer
Koochaki, P., Qiu, B., Coker, J. A., Earsley, A., Wang, N. S., Romigh, T., Goins, C. M., Salem, C., Mi, D., Days, E., Bauer, J., Stauffer, S. R., Boudker, O., Chakraborty, A. A.
10.1101/2025.07.03.663021 — Posted: 2026-03-19
Quinone reductase 2 reads H3 serotonylation to support neuronal maturation
Chen, M., Yang, C., Li, X., Kong, L., Weekley, B. H., Wei, X., O'Chan, J. C., Vinson, D. A., Cetin, B., Ramakrishnan, A., Shen, L., Zeng, R., Liu, Z., Zhang, J., Cappuccio, K. M., Sokol, J. R., Baljinnyam, E., Hu, R., Rosenblum, K., Molina, H., Zheng, Q., David, Y., Marro, S. G., Muir, T. W., Li, X. D., Li, H., Maze, I.
10.64898/2026.03.17.712426 — Posted: 2026-03-19
Combining brain-wide activity imaging with electron microscopy reveals a distributed nociceptive network in the brain
Randel, N., Wang, C., Clayton, M. S., Wang, K., Pang, S., Xu, S. C., Champion, A., Hess, H. F., Cardona, A., Keller, P. J., Zlatic, M.
10.1101/2025.09.25.678485 — Posted: 2026-03-19
Genome-scale functional mapping of the mammalian whole brain with in vivo Perturb-seq
Shi, T., Korshunova, M., Kim, S., DeTomaso, D., Zheng, X., Vishvanath, L., Nyasulu, T., Huynh, N., Sun, A., Thompson, P. C., Zhang, Y., Wigdor, E. M., Rohani, N., Ali, S., Qiu, H., Geralt, M., Zhao, Z., Rabhi, S., Yao, Z., van Velthoven, C. T., Nery, J. R., Castanon, R. G., Dicks, S., Chen, T. J., Ecker, J. R., Zeng, H., Zheng, G. X., Sanders, S. J., Sundaram, L., Jin, X.
10.64898/2026.03.16.711480 — Posted: 2026-03-18
Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures
Ahn, J. J., Yu, T. C., Dadonaite, B., Radford, C. E., Bloom, J. D.
10.64898/2026.01.05.697808 — Posted: 2026-03-18
Midgestation metabolic constraint in purine metabolism drives distinct strategies for placenta and fetal growth
Xu, W., De La Cruz, N., Woods, A., Lokshtanov, D., Gao, S., Khan, N. A., Wright, S., Florian-Rodriguez, M., McIntire, D. D., Duryea, E. L., Nelson, D. B., Spong, C. Y., Herrera, C. L., Hanna, J. H., Srivatsan, S. R., Aguilera Castrejon, A., Solmonson, A.
10.64898/2026.03.18.712680 — Posted: 2026-03-18
Heterotypic intercellular adhesion tunes efficiency of cell-on-cell migration
Kuyyamudi, C., Ghosh, S., Extavour, C. G.
10.1101/2025.08.29.673192 — Posted: 2026-03-18
Reconstituting Mouse Embryogenesis Ex Utero from Gastrulation to Fetal Development Reveals Maternally Independent Metabolic Programs
Lokshtanov, D., Gao, S. M., Xu, W., Kosman, A., Roncato, F., De La Cruz, N., Khan, N. A., Woods, A., Campbell, I., Woehler, A., Christoforou, C., Ding, L., Hu, A., Copeland, M., Wang, L., Yang, X., Raley, C., Delventhal, K., Herrera, A., Valente, A., Wright, S., Gomez-Cesar, E., Shlomo, R., Golenchenko, S., Oldak, B., Yilmaz, A., Gurhan-Sevinc, G., Comar, M.-Y., Viukov, S., Novershtern, N., Zhang, H., Duong, T., Li, L., Khatib, N., Kakun, R. R., Espinosa-Medina, I., Florian-Rodriguez, M. E., LaManno, G., Tillberg, P. W., Wang, M. C., Maza, I., Srivatsan, S., Solmonson, A., Hanna, J. H., Aguile
10.64898/2026.03.17.710314 — Posted: 2026-03-18

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