Channel:  The Howard Hughes Medical Institute (HHMI)

2,326 Articles

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mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion
Gentile, C., Feng, W. W., Lenahan, S. M., Ying, A. W., Card, D. C., Wu, F. T. H., Pham, N.-A., Radulovich, N., Cao, P. M., Hueniken, K., Li, Q., Tsao, M.-S., Kulesza, J., Hinkley, M. M., Liao, L., Tsai, J. A. < A., Kohler, J., Facchinetti, F., Li, J., Weston, C., Locquet, M.-A., Ngo, K., Gokhale, P. C., Sacher, A. G., Janne, P. A., Kadoch, C.
10.64898/2026.02.27.708377 — Posted: 2026-03-01
Structural basis of RNA-guided transcription by a dCas12f-σE-RNAP complex
Xiao, R., Hoffmann, F. T., Xie, D., Wiegand, T., Palmieri, A. I., Sternberg, S. H., Chang, L.
10.1101/2025.06.10.658880 — Posted: 2026-02-28
Exapted CRISPR-Cas12f homologs drive RNA-guided transcription
Hoffmann, F. T., Wiegand, T., Palmieri, A. I., Glass-Klaiber, J., Xiao, R., Tang, S., Le, H. C., Meers, C., Lampe, G. D., Chang, L., Sternberg, S. H.
10.1101/2025.06.10.658865 — Posted: 2026-02-28
Vampire bats target their social grooming to hard-to-reach body parts
Chen, C., Nguyen, T. I., Meyer, M., Hashem, E., Carter, G. G.
10.64898/2026.02.25.707567 — Posted: 2026-02-28
The deubiquitinating enzyme Otu1 releases substrates from the conserved initiation complex of the Cdc48/p97 ATPase for proteasomal degradation
Li, H., Guan, H., Rapoport, T.
10.1101/2025.11.08.687396 — Posted: 2026-02-28
Exploratory analyses of Immunologic Features in a Randomized, Placebo-Controlled Trial of Nirmatrelvir/Ritonavir for Long COVID
Bhattacharjee, B., Sawano, M., Hooper, W. B., Wang, K., Tabachnikova, A., Monteiro, V. S., Lu, P., Baevova, P., Rodrigues, G. C., Fisher, V. L., Caraballo, C., Khera, R., Li, S.-X., Herrin, J., Christian, D., Coppi, A., Warner, F., Holub, J., Henriquez, Y., Johnson, M. A., Goddard, T. B., Rocco, E., Hummel, A. C., Mouslmani, M. A., Carr, K. D., Charnas, L., Jesus, M. D., Nepert, D., Abreu, P., Ziegler, F. W., Spertus, J., Guan, L., Krumholz, H., Iwasaki, A.
10.64898/2026.02.24.26347001 — Posted: 2026-02-26
Aspartate aminotransferase is required for Salmonella expansion in the inflamed gut via TCA anaplerosis
Shealy, N. G., Baltagulov, M., Avalos, H. F., Olivas, J., Jones, K. M., Byndloss, M. X.
10.64898/2026.02.24.707732 — Posted: 2026-02-26
Gaussian Process Inference Reveals Non-separability of Positionand Velocity Tuning in Grid Cells
Warton, L., Ganguli, S., Giocomo, L.
10.64898/2026.02.02.703269 — Posted: 2026-02-26
A druggable redox switch on SHP1 controls macrophage inflammation
Ng, M. Y., Nix, M. N., Du, G., Davidek, I., Burger, N., Shin, S., Toenjes, S., Takeda, H., Cheah Xin Yan, M., Zhang, B., Xiao, H., Wei, S., Seo, H.-S., Dhe-Paganon, S., Wales, T. E., Engen, J., Mills, E., Che, J., Zhang, T., Gray, N., Chouchani, E. T.
10.64898/2026.02.19.706790 — Posted: 2026-02-26
Superabundant microRNAs are transcribed from human rDNA spacer promoters insulated by CTCF
Henikoff, S., Henikoff, J. G.
10.1101/2025.11.10.687711 — Posted: 2026-02-26

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