Channel:  The Howard Hughes Medical Institute (HHMI)

2,394 Articles

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Structure and Mechanism of a Two-component Lanthipeptide Toxin
Moreira, R., Giurgiu, C., Rahman, I. R., Patterson, M., Huber, S. T., Yang, Y., Jeanne Dit Fouque, K., Fernandez-Lima, F., Liu, G., Guo, R., Kelich, P., Wen, P.-C., Tajkhorshid, E., Johnson, A. G., van der Donk, W. A.
10.64898/2026.05.13.724966 — Posted: 2026-05-14
First Lithic Age Caribbean genomes document pre-Ceramic genetic continuity and affinities to Central America and northern South America
Sirak, K., Lopez Belando, A. J., Shelley, D., Arevalo, M. G., Shelley, D., Mallick, S., Rohland, N., Reich, D. E.
10.64898/2026.05.12.724636 — Posted: 2026-05-13
Promoter strength and position govern promoter competition via transcript-dependent insulation
Koska, M., Nagano, M., Swigut, T., Boettiger, A. N., Hansen, A. S., Wysocka, J.
10.1101/2025.05.06.652547 — Posted: 2026-05-13
WATER reveals heterochrony of molecular programs underlies developmental failure caused by minor spliceosome inhibition
Springer, S. M., Boria, A. R., Drake, K. D., Afriyie, K. O., Girardini, K. N., Konakanchi, T., Stevens, I., Camacho, N., Lopes, T., Kanadia, R. N.
10.64898/2026.05.08.723603 — Posted: 2026-05-13
Spatial distribution of blood-brain barrier membrane proteins is controlled by sorting motifs and physiological signals in vivo
Amick, J., Bhandarkar, S., Wilcox, D. R., Boloker, S., Gu, C.
10.64898/2026.05.10.724157 — Posted: 2026-05-13
δ-catenin controls layer-specific transcriptional maturation of astrocytes via Zbtb20
Sejourne, G., Tan, C. X., Savage, J. T., Manigault, G., Richardson, G., Ding, J., Hardin, E. J., Ramirez, J., Baumert, R., Sakers, K., Eroglu, C.
10.64898/2026.05.12.724361 — Posted: 2026-05-13
PCanPIE: A group I intron platform for efficient circRNA synthesis at ambient temperatures
Warkentin, R., Pyle, A. M.
10.64898/2026.05.11.724386 — Posted: 2026-05-12
Replaying germinal center evolution on a quantified affinity landscape
DeWitt, W. S. S., Vora, A. A., Araki, T., Galloway, J. G., Alkutkar, T., Bortolatto, J., Castro, T. B., Dumm, W., Jennings-Schaffer, C., Jia, T., Mesin, L., Ozorowski, G., Pae, J., Ralph, D. K., Bloom, J. D., Nourmohammad, A., Song, Y. S., Ward, A., Starr, T. N., Matsen, F. A., Victora, G. D.
10.1101/2025.06.02.656870 — Posted: 2026-05-12
The transcriptional and translational outcomes for pseudogenes in bacterial endosymbionts
Garber, A., Nwachukwu, J., Stikeleather, R., York, C., McCutcheon, J.
10.64898/2026.02.04.703838 — Posted: 2026-05-12
Targeting an RNA Editor to Impede H3K27M+ Pediatric Gliomas
Ramsoomair, C. K., Alvarez, V., Sarmiento, F., Aramburu Berckemeyer, M., Seetharam, D., Kalliecharan, K., Moorkkannur, S. N., Mitchell, J., Hudson, A., Taylor, J., Ceccarelli, M., Bayik, D., Becher, O. J., Prabahakar, R., Welford, S., Gampel, B., De Carvalho, D. D., Reinberg, D., Shah, A. H.
10.64898/2026.05.08.723800 — Posted: 2026-05-12

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