Channel:  The Howard Hughes Medical Institute (HHMI)

1,958 Articles

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Uncovering the molecular basis of kinase activity and substrate recognition with phospho-PCA
Yu, C., Pao, E., Van Valen, D. A.
10.1101/2025.11.07.687244 — Posted: 2025-11-13
Cap1 forms a cyclic tetra-adenylate-induced membrane pore during the type III-A CRISPR-Cas immune response
Majumder, P., Cahir, C. W., Roberts, C. G., Patel, D. J., Marraffini, L. A.
10.1101/2025.11.13.688252 — Posted: 2025-11-13
Proteome-wide in silico screening for human protein-protein interactions
Schmid, E., Zhu, H., Ryu, E., Lim, Y., Smogorzewska, A., Brown, A., Walter, J.
10.1101/2025.11.10.687652 — Posted: 2025-11-12
Insights into the regulation of VPS13 family bridge-like lipid transfer proteins from the structure of VPS13C.
Li, D., Wang, X., Hu, B., Hao, H., Hamill, S., Li, Y., Chen, G., De Camilli, P., Reinisch, K.
10.1101/2025.11.10.687702 — Posted: 2025-11-11
The deubiquitinating enzyme Otu1 releases substrates from the conserved initiation complex of the Cdc48/p97 ATPase for proteasomal degradation
Li, H., Guan, H., Rapoport, T.
10.1101/2025.11.08.687396 — Posted: 2025-11-11
Insertion of an invading retrovirus regulates a novel color trait in swordtail fish
Haghani, N., Dodge, T. O., Baczenas, J. J., Gunn, T., He, Q., Pangburn, W., Sood, R., Du, K., Fascinetto-Zago, P., Kaatmann, A., Ou, Z., Dougan, S., Olmos-Santiago, N. S., Preising, G. A., Payne, C. Y., Haase Cox, S. K., Hunnicutt, K. E., Madrzyk, M., Moran, B. M., Stigloher, C., Powell, D. L., Schartl, M., Gifford, C., Han, G. z., Schumer, M.
10.1101/2025.11.07.687308 — Posted: 2025-11-11
Structure-informed evolutionary analysis of the meiotic recombination machinery
Arter, M., Vedanayagam, J., Lu, M., Diop, M., Liu, K., Lai, E. C., Keeney, S.
10.1101/2025.11.07.687317 — Posted: 2025-11-11
Canonical transcription termination mechanisms explain a minority of operons in cyanobacteria
Cascino, J. A., Dierksheide, K. J., Vishwakarma, R. K., Yuzenkova, Y., Babitzke, P., Murakami, K., Li, G.-W.
10.1101/2025.11.10.687660 — Posted: 2025-11-10
Mus Musculus papillomavirus MmuPV1 resists restriction by human APOBEC3B
Liu, X., Bilger, A., Lee, D., Argyris, P., Chen, J., Ward-Shaw, E., Barreto Duran, E., Lin, Y.-H., Durfee, C., Chun, S. H., Ibrahim, M., Proehl, J., Allen, Y., Lambert, P. F., Harris, R. S.
10.1101/2025.11.10.687577 — Posted: 2025-11-10
Brain-wide coordination of internal signals during decision-making
Bondy, A. G., Charlton, J. A., Luo, T. Z., Kopec, C. D., Stagnaro, W. M., Venditto, S. J. C., Lynch, L., Janarthanan, S., Oline, S. N., Harris, T. D., Brody, C. D.
10.1101/2024.08.21.609044 — Posted: 2025-11-10

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