Channel:  The Howard Hughes Medical Institute (HHMI)

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Atom level enzyme active site scaffolding using RFdiffusion2
Ahern, W., Yim, J., Tischer, D., Salike, S., Woodbury, S., Kim, D., Kalvet, I., Kipnis, Y., Coventry, B., Altae-Tran, H., Bauer, M., Barzilay, R., Jaakkola, T., Krishna, R., Baker, D. A.
10.1101/2025.04.09.648075 — Posted: 2025-04-10
OmniSplice: a framework-free splicing event reporter
Lannes, R., Fingerhut, J. M., Yamashita, Y. M. M.
10.1101/2025.04.06.647416 — Posted: 2025-04-08
Transcription factor hubs exhibit gene-specific properties that tune expression
Fallacaro, S., Mukherjee, A., Turner, M. A., Garcia, H. G., Mir, M.
10.1101/2025.04.07.647578 — Posted: 2025-04-08
Biosynthesis of Macrocyclic Peptides by Formation and Crosslinking of ortho-Tyrosines
Padhi, C., Zhu, L., Chen, J. Y., Moreira, R., van der Donk, W. A.
10.1101/2025.04.04.647296 — Posted: 2025-04-08
Small-molecule modulation of Beta-arrestins
Kahsai, A. W., Pakharukova, N., Kwon, H. Y., Shah, K. S., Liang-Lin, J. G., del Real, C. T., Shim, P. J., Lee, M. A., Ngo, V. A., Shreiber, B. N., Liu, S., Schwalb, A. M., Espinoza, E. F., Thomas, B. N., Kunzle, C. A., Smith, J. S., Wang, J., Kim, J., Zhang, X., Rockman, H. A., Thomsen, A. R. B., Rein, L. A. M., Shi, L., Ahn, S., Masoudi, A., Lefkowitz, R. J.
10.1101/2024.12.27.630464 — Posted: 2025-04-08
Geospatial and demographic patterns of SARS-CoV-2 spread in Massachusetts from over 130,000 genomes
Moreno, G. K., Brock-Fisher, T., Krasilnikova, L. A., Schaffner, S., Burns, M., Casiello, C. E., Messer, K. S., Petros, B. A., Specht, I., DeRuff, K. C., Siddle, K. J., Loreth, C., Fitzgerald, N. A., Rooke, H. M., Gabriel, S. B., Smole, S., Wohl, S., Park, D. J., Madoff, L. C., Brown, C. M., MacInnis, B. L., Sabeti, P. C.
10.1101/2025.04.04.25324273 — Posted: 2025-04-06
Lipid metabolism of hepatocyte-like cells supports intestinal tumor growth by promoting tracheogenesis
Huang, K., Miao, T., Dantas, E., Han, M., Hu, Y., Wang, K., Sanford, J., Goncalves, M., Perrimon, N.
10.1101/2025.04.04.647255 — Posted: 2025-04-05
Superinfection with intact HIV-1 results in conditional replication of defective proviruses and nonsuppressible viremia in people living with HIV-1
Hariharan, V., White, J. A., Dragoni, F., Fray, E. J., Pathoulas, N., Moskovljevic, M., Zhang, H., Singhal, A., Lai, J., Beg, S. A., Scully, E. P., Gilliams, E. A., Block, D. S., Keruly, J., Moore, R. D., Siliciano, J. D., Simonetti, F. R., Siliciano, R. F.
10.1101/2025.04.04.647291 — Posted: 2025-04-04
Perinatal Elimination of Genetically Aberrant Neurons from Human Cerebral Cortex
Shao, D. D., Zhao, Y., Brew, J., Ghosh, U., Luquette, L. J., Zhao, S., Kriz, A. J., Qian, X., Viswanadham, V. V., Taketomi, T., Tsuruta, F., Park, P. J., Walsh, C. A.
10.1101/2024.10.08.617159 — Posted: 2025-04-03
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM
Hanna, M. G., Rodriguez Cruz, H. O., Fujise, K., Wu, Y., Xu, C. S., Pang, S., Zhuoning, L., Monetti, M., De Camilli, P.
10.1101/2024.09.28.615015 — Posted: 2025-04-03

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