Channel:  The Howard Hughes Medical Institute (HHMI)

2,121 Articles

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PfApiAT2 is a proline transporter essential for the transmission of Plasmodium falciparum by the mosquito vector.
Khushu, M., Kissel, R. C., Kauffman, J., Taccheri, C., Singh, N., Summers, R. L., Plant, L. D., Wirth, D., Catteruccia, F., Bopp, S.
10.64898/2026.01.20.700404 — Posted: 2026-01-20
Decoding the cell intrinsic and extrinsic roles of PRC2 in early embryogenesis
Zhou, C., Wang, M., Chen, Z., Zhang, Y.
10.64898/2026.01.20.700679 — Posted: 2026-01-20
Selective Immune Silencing by Targeted TGF-β Agonists
Sun, Q., Ogishi, M., Jiang, H., Barrett, A. K., Yan, H., Sola, E., Zhang, J., Xiao, P., Lyu, H., Salehi, A., Tang, Q., Lanz, T. V., Davis, M. M., Negrin, R. S., Garcia, K. C.
10.64898/2026.01.19.700410 — Posted: 2026-01-20
Cytoplasmic mRNA decay by the anti-viral nuclease RNase L promotes transcriptional repression
Mao, X., Tokamov, S., Pahmeier, F., Lari, A., Xu, J., Harris, E., Glaunsinger, B.
10.1101/2025.07.08.663778 — Posted: 2026-01-19
B Lymphocyte Protein Factories produced by Hematopoietic Stem Cell Gene Editing
Hartweger, H., Ruprecht, C., Yao, K.-H., Laffont, P., Lima dos Reis, G., Zhou, P., Hägglöf, T., Binet, L., Loewe, M., Hong, J. P., Xiao, T., Sefik, E., Hernandez, B., Gazumyan, A., Jankovic, M., Seaman, M. S., Costa, G., Nelson, S. A., Clark, J., Kanatani, S., Wilson, P. C., Krammer, F., Levashina, E. A., Julien, J.-P., Wardemann, H., Sinnis, P., Stamatatos, L., Flavell, R. A., Nussenzweig, M. C.
10.64898/2026.01.16.699998 — Posted: 2026-01-18
Modular mRNA LNP design integrates RNA, lipid, and antigen engineering for protective vaccination
Farzani, T., Espinoza, N., M. Manafi, M., R. Welch, S., D. Coleman-McCray, J., Aida-Ficken, V., R. Spengler, J., Bergeron, E., F. Spiropoulou, C., Borges, C., Bielecki, K., Li, L., Shah, D., Paye, M., Rojas, E., N. Spector, S., Samani, P., E. Hensley, L., Ozonoff, A., Sabeti, P.
10.64898/2026.01.17.699915 — Posted: 2026-01-18
Discovery of a Human Metabolite that Mimics the Bacterial Quorum-Sensing Autoinducer AI-2
Shine, E., Valastyan, J. S., Ying, V. Y., Huang, J. Z., Seyedsayamdost, M. R., Bassler, B. L.
10.64898/2026.01.16.699917 — Posted: 2026-01-17
Monitoring of plasma and urine tumor-derived DNA to inform bladder-sparing approaches for patients with muscle-invasive bladder cancer
Galsky, M. D., Izadmehr, S., Yu, M., Curtis, S. D., Douville, C., Popoli, M., Ptak, J., Dobbyn, L., Silliman, N., Chan, K. G., Dorff, T. B., Cetnar, J. P., O'Neil, B., D'Souza, A., Mamtani, R., Kyriakopoulos, C. E., Brody, R., Sadimin, E., Mehrazin, R., Chowell, D., Sfakianos, J., Daneshmand, S., Pal, S. K., Bettegowda, C., Kinzler, K. W., Papadopoulos, N., Vogelstein, B., Wang, Y.
10.64898/2026.01.14.26344033 — Posted: 2026-01-16
Hypomethylation on cfDNA within transposable elements can predict ovarian malignancy in women with adnexal masses
Weigert, M., Cui, X., Zhang, P., Kowitwanich, K., West-Szymanski, D., Rauch, S., Zhang, W., He, C., Lengyel, E.
10.64898/2026.01.14.26344128 — Posted: 2026-01-16
Tumor-induced orexigenic imbalance lowers protein appetite and drives early organ wasting symptoms
Petsakou, A., Filine, E., Li, M., Chen, Y., Zheng, A., Perrimon, N.
10.1101/2025.01.02.631110 — Posted: 2026-01-16

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