Channel: The Howard Hughes Medical Institute (HHMI)

2,317 Articles

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Positive Selection Screen Identifies Natural Product β-Catenin Inactivators

Boudreau, M. W., Freire, V. F., Corbett, S. C., Martinez-Fructuoso, L., Shenoy, S. R., Yu, W., Kumar, R., Thornburg, C. C., Akee, R. K., Peyser, B. D., Jiang, Q., Splaine, J., Pfaff, J. L., Chandler, B. C., Abeja, D. M., Donovan, K. A., Che, J., Lampson, B. L., Cooke, M., Kazanietz, M. G., Szajner, P., Smith, J. A., Koduri, V., Grkovic, T., OKeefe, B. R., Kaelin, W. G.

10.1101/2025.08.27.671140 — Posted: 2026-04-17

A transcription factor-sRNA-mediated double-negative feedback loop confers pathogen-specific control of quorum-sensing genes

Mashruwala, A. A., Decker, K., Fei, C., Valastyan, J. S., Bassler, B. L.

10.1101/2025.08.22.671807 — Posted: 2026-04-17

Cellulose Synthase Complexes and Remorins Mediate Stress Resilience Through Cell Wall-Plasma Membrane Attachments

Rui, Y., Zaoralova, M., Dwyer, W. P., Reyes, A. V., Grismer, T. S., Abel, N. B., Jayachandran, D., Chundawat, S. P. S., Ott, T., Kieber, J. J., Dahlberg, P., Xu, S.-L., Dinneny, J. R.

10.1101/2025.08.01.664786 — Posted: 2026-04-17

Rhizobacterial Biosensors Spatially Map Natural and Engineered Sucrose Exudation

Dundas, C. M., Brinkman, G. A., Clarke, T., Payne, M., Ureta, J. A., Velasco, I., Wallace, J. G., Dinneny, J. R.

10.64898/2026.04.15.718812 — Posted: 2026-04-16

Intranasal Anti-CD3 Antibody Treatment Attenuates Post-COVID Neuroinflammation and Enhances Hippocampal Neurogenesis and Cognitive Function in Mice

Lu, P., Izzy, S., Da Silva, P., Imkamp, H. T., Christenson, J. R., Yahya, T., Mansi, M. H. A., Alawi, A., Moreira, T. G., Monje, M., Weiner, H. L., Iwasaki, A.

10.64898/2026.04.07.716934 — Posted: 2026-04-16

Controlled linking of AAV capsids enables coordinated multi-vector delivery

Kim, Y., Ding, X., Yang, C., Lee, G., Gradinaru, V., Park, J.

10.64898/2026.04.13.716639 — Posted: 2026-04-16

DIOPT: the DRSC Integrative Ortholog Prediction Tool, 2026 update

Hu, Y., Comjean, A., Gao, C., Yamamoto, S., Mohr, S., Perrimon, N.

10.64898/2026.04.15.718708 — Posted: 2026-04-16

Track Display Jockey (trackDJ): a user-friendly R package for visualization of epigenomic data

Bokil, N. V., Page, D. C.

10.64898/2026.04.15.718328 — Posted: 2026-04-16

Apical Localization of RNA Polymerases Modulates Transcription Dynamics and Supercoiling Domains Revealed by Cryo-ET

Zhang, M., Canari-Chumpitaz, C., Liu, J., Onoa, B., de Cleir, S., Cheng, E., Requejo, K. I., Bustamante, C.