Channel:  The Howard Hughes Medical Institute (HHMI)

1,286 Articles

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Courtship song differs between African and European populations of Drosophila melanogaster and involves a strong effect locus
Lollar, M. J., Kim, E., Stern, D. L., Pool, J. E.
10.1101/2024.05.14.594231 — Posted: 2025-02-24
Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15
Davidson, J., Jain, R., Kizzar, T., Geoghegan, G., Nesbitt, D. J., Cavanagh, A. T., Abe, A., Hunger, A., Chao, X., James, I., Baldwin, D., Verma, R., Schueler, K. L., Hinkoka-Galcheva, V., Michorowska, S., Shishkova, E., Ding, W.-X., Coon, J. J., Shayman, J., Simcox, J.
10.1101/2023.11.03.565498 — Posted: 2025-02-20
Single-cell type analysis of wing premotor circuits in the ventral nerve cord of Drosophila melanogaster
Ehrhardt, E., Whitehead, S. C., Namiki, S., Minegishi, R., Siwanowicz, I., Feng, K., Otsuna, H., FlyLight Project Team, , Meissner, G. W., Stern, D., Truman, J., Shepherd, D., Dickinson, M. H., Ito, K., Dickson, B. J., Cohen, I., Card, G. M., Korff, W.
10.1101/2023.05.31.542897 — Posted: 2025-02-20
CellSAM: A Foundation Model for Cell Segmentation
Israel, U., Marks, M., Dilip, R., Li, Q., Yu, C., Laubscher, E., Iqbal, A., Pradhan, E., Ates, A., Abt, M., Brown, C., Pao, E., Li, S., Pearson-Goulart, A., Perona, P., Gkioxari, G., Barnowski, R., Yue, Y., Van Valen, D. A.
10.1101/2023.11.17.567630 — Posted: 2025-02-17
Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder
Song, B. J., Ge, Y., Nicolella, A., Kwon, M. J., Lodder, B., Bonanno, K., Valle-Tojeiro, A., Mandell, K. P., Adeleye, J., Geng, C., Natarajan, S., Picard, I., Shepard, N., Aryal, S., Farsi, Z., Liu, X.-M., Morshed, N., Nadaf, N. M., Pribiag, H., Simmons, S. K., Mani, D. R., Stevens, B., Macosko, E. Z., Levin, J. Z., Sabatini, B. L., Keshishian, H., Carr, S. A., Dejanovic, B., Granger, A. J., Sheng, M.
10.1101/2024.09.24.614783 — Posted: 2025-02-15
CARD8 inflammasome activation during HIV-1 cell-to-cell transmission
Kulsuptrakul, J., Emerman, M., Mitchell, P. S.
10.1101/2024.08.21.608981 — Posted: 2025-02-15
Evidence accumulation from experience and observation in the cingulate cortex
Chen, R., Radkani, S., Valluru, N., Yoo, S. B., Jazayeri, M.
10.1101/2025.02.13.638172 — Posted: 2025-02-14
Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2
Raig, N. D., Surridge, K. J., Sanz-Murillo, M., Dederer, V., Kramer, A., Schwalm, M. P., Elson, L., Chatterjee, D., Mathea, S., Hanke, T., Leschziner, A. E., Reck-Peterson, S. L., Knapp, S.
10.1101/2024.09.17.613365 — Posted: 2025-02-13
Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors
Ni, X., Richardson, R. B., de Godoy, A. S., Ferla, M. P., Kikawa, C., Scheen, J., Hannon, W. W., Capkin, E., Lahav, N., Balcomb, B. H., Marples, P. G., Fairhead, M., Wang, S., Williams, E., Tomlinson, C. W. E., Aschenbrenner, J. C., Lithgo, R., Winokan, M., Girould, C., Chandran, A. V., Walsh, M. A., Thompson, W., Bloom, J. D., Barr, H., Kirkegaard, K., Koekemoer, L., Fearon, D., Evans, M. J., von Delft, F.
10.1101/2024.04.29.591502 — Posted: 2025-02-13
Distinct Neural Representations of Hunger and Thirst in Neonatal Mice before the Emergence of Food- and Water-seeking Behaviors
Wang, D. C., Wu, Y., Mehaffey, C., Espinoza-Campomanes, L. A., Santos-Valencia, F., Franks, K., Luo, L.
10.1101/2024.09.22.614378 — Posted: 2025-02-13

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