Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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CARD8 inflammasome activation during HIV-1 cell-to-cell transmission
Kulsuptrakul, J., Emerman, M., Mitchell, P. S.
10.1101/2024.08.21.608981 — Posted: 2025-02-15
Evidence accumulation from experience and observation in the cingulate cortex
Chen, R., Radkani, S., Valluru, N., Yoo, S. B., Jazayeri, M.
10.1101/2025.02.13.638172 — Posted: 2025-02-14
Distinct Neural Representations of Hunger and Thirst in Neonatal Mice before the Emergence of Food- and Water-seeking Behaviors
Wang, D. C., Wu, Y., Mehaffey, C., Espinoza-Campomanes, L. A., Santos-Valencia, F., Franks, K., Luo, L.
10.1101/2024.09.22.614378 — Posted: 2025-02-13
STHD: probabilistic cell typing of single Spots in whole Transcriptome spatial data with High Definition
Sun, C., Zhang, Y.
10.1101/2024.06.20.599803 — Posted: 2025-02-13
Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2
Raig, N. D., Surridge, K. J., Sanz-Murillo, M., Dederer, V., Kramer, A., Schwalm, M. P., Elson, L., Chatterjee, D., Mathea, S., Hanke, T., Leschziner, A. E., Reck-Peterson, S. L., Knapp, S.
10.1101/2024.09.17.613365 — Posted: 2025-02-13
Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors
Ni, X., Richardson, R. B., de Godoy, A. S., Ferla, M. P., Kikawa, C., Scheen, J., Hannon, W. W., Capkin, E., Lahav, N., Balcomb, B. H., Marples, P. G., Fairhead, M., Wang, S., Williams, E., Tomlinson, C. W. E., Aschenbrenner, J. C., Lithgo, R., Winokan, M., Girould, C., Chandran, A. V., Walsh, M. A., Thompson, W., Bloom, J. D., Barr, H., Kirkegaard, K., Koekemoer, L., Fearon, D., Evans, M. J., von Delft, F.
10.1101/2024.04.29.591502 — Posted: 2025-02-13
A lateralized pathway for associating nutrients with flavors
Grove, J. C. R., Li, Q., Backes, H., Kuzmanovic, B., Choi, J., Ubadiah, V., Qiu, L., Zhang, J., Liu, Z., Small, D. M., Tittgemeyer, M., Knight, Z. A.
10.1101/2025.02.09.637334 — Posted: 2025-02-10
Evaluation of sequencing reads at scale using rdeval
Formenti, G., Koo, B., Sollitto, M., Balacco, J., Brajuka, N., Burhans, R., Duarte, E., Giani, A. M., McCaffrey, K., Medico, J. A., Myers, E. W., Smeds, P., Nekrutenko, A., Jarvis, E. D.
10.1101/2025.02.01.636073 — Posted: 2025-02-08
Cutaneous lupus features specialized stromal niches and altered retroelement expression
Gehlhausen, J. R., Kong, Y., Baker, E., Ramachandran, S., Koumpouras, F., Ko, C., Vesely, M., Little, A., Damsky, W., King, B., Iwasaki, A.
10.1101/2025.02.01.636053 — Posted: 2025-02-06
De novo design of Ras isoform selective binders
Zhang, J. Z., Li, X., Liu, C., Jiang, H., Wu, K., Baker, D.
10.1101/2024.08.29.610300 — Posted: 2025-02-05

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