Channel:  The Howard Hughes Medical Institute (HHMI)

2,393 Articles

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In vitro-reconstituted Drosophila Arc capsids deliver gene editors to dystrophic muscle
Lash, B., Strebinger, D., Segel, M., Vo, S., Delong, K., Pham, J., Swan, C., Kumar, P., Zhang, Y., Liu, C., Mok, J., Macrae, R., Zhang, F.
10.64898/2026.05.25.727180 — Posted: 2026-05-25
The Structural Basis of Malodorant Skatole Formation by the Glycyl Radical Enzyme Indoleacetate Decarboxylase
Imrich, C. N., Backman, L. R. F., Allworth, A. P., Andorfer, M. C., Paris, J. C., Greeley, N. M., Fu, B., Balskus, E. P., Drennan, C. L.
10.64898/2026.05.24.727522 — Posted: 2026-05-25
Combined Disruption of Multiple Cytokine Signaling Pathways Enables One-Step Anterograde Tracing with Vesicular Stomatitis Virus
Ma, X., Cepko, C. L.
10.64898/2026.05.22.727255 — Posted: 2026-05-25
PIEZO1-mediated mechanosensation links aging to bladder dysfunction
Hamed, Y. M. F., Joshi, V., Wilhelm, K., Romero, L. O., Solomon, O. D., Kwok, T. B., Lopez Gonzalez, E. D., Ridlon, M. M., Pendyala, S., Calhoun, C. M., Martinez, A. E., Asmussen, J. K., Keil Stietz, K., Vezina, C. M., Vasquez, V., Lichtarge, O., Beyder, A., Marshall, K. L.
10.64898/2026.05.24.726025 — Posted: 2026-05-25
Spatial Regulation of CAR Signaling Enables Logic-Gated Activity
Nichakawade, T. D., Mog, B., Pearlman, A. D., Ahmedna, T. S., Marcou, N., Mora-Cartin, R., Watson, E., Seok Lee, B., DiNapoli, S. R., Papadopoulos, N., Bettegowda, C., Dal Molin, M., Wirtz, D., Pardoll, D. M., Paul, S., Sur, S., Gabrielson, K. L., Zhou, S., Vogelstein, B., Kinzler, K. W.
10.64898/2026.05.22.726983 — Posted: 2026-05-24
How many genes can CRISPR edit to engineer complex adaptations?
Kyung, J., Esfahanian, M., Mann, J., Koke, E., Pham, K., Peng, Y., Exposito-Alonso, M.
10.64898/2026.05.21.726991 — Posted: 2026-05-23
Entrenchment of germline amino-acid differences in antibody affinity maturation
Harel, N., Sung, K., Dumm, W., Johnson, M. M., Rich, D., Fukuyama, J., Haddox, H. K., Matsen, F. A.
10.64898/2026.04.21.720000 — Posted: 2026-05-23
Developmental conversion of the nucleolus into an RNA Polymerase II transcriptional platform in Drosophila spermatocytes
Fingerhut, J. M. M., Park, J. I., Li, R. Y., Lannes, R., Ashok, A., Yamashita, Y. M.
10.64898/2026.05.20.726666 — Posted: 2026-05-23
Molecular underpinning of Hydra viridissima-algal facultative symbiosis and vertical algal transmission
Tran, J. R., Sittmann, J., Ma, B., Zhu, M., Zheng, Y., Hu, M.
10.64898/2026.05.21.726902 — Posted: 2026-05-23
The Rossmann2x2 Fold Attains its Native Structure Via a Defined Pathway of Sequential and Cooperative Folding Units
Bustamante, C. J.
10.64898/2026.05.21.726993 — Posted: 2026-05-22

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