Channel:  The Howard Hughes Medical Institute (HHMI)

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The deubiquitinating enzyme Otu1 releases substrates from the conserved initiation complex of the Cdc48/p97 ATPase for proteasomal degradation
Li, H., Guan, H., Rapoport, T.
10.1101/2025.11.08.687396 — Posted: 2025-11-11
Insertion of an invading retrovirus regulates a novel color trait in swordtail fish
Haghani, N., Dodge, T. O., Baczenas, J. J., Gunn, T., He, Q., Pangburn, W., Sood, R., Du, K., Fascinetto-Zago, P., Kaatmann, A., Ou, Z., Dougan, S., Olmos-Santiago, N. S., Preising, G. A., Payne, C. Y., Haase Cox, S. K., Hunnicutt, K. E., Madrzyk, M., Moran, B. M., Stigloher, C., Powell, D. L., Schartl, M., Gifford, C., Han, G. z., Schumer, M.
10.1101/2025.11.07.687308 — Posted: 2025-11-11
Structure-informed evolutionary analysis of the meiotic recombination machinery
Arter, M., Vedanayagam, J., Lu, M., Diop, M., Liu, K., Lai, E. C., Keeney, S.
10.1101/2025.11.07.687317 — Posted: 2025-11-11
Insights into the regulation of VPS13 family bridge-like lipid transfer proteins from the structure of VPS13C.
Li, D., Wang, X., Hu, B., Hao, H., Hamill, S., Li, Y., Chen, G., De Camilli, P., Reinisch, K.
10.1101/2025.11.10.687702 — Posted: 2025-11-11
Brain-wide coordination of internal signals during decision-making
Bondy, A. G., Charlton, J. A., Luo, T. Z., Kopec, C. D., Stagnaro, W. M., Venditto, S. J. C., Lynch, L., Janarthanan, S., Oline, S. N., Harris, T. D., Brody, C. D.
10.1101/2024.08.21.609044 — Posted: 2025-11-10
PHA-4/FoxA controls the function of pharyngeal and extrapharyngeal enteric neurons of C. elegans
Walker, Z., Cao, W. X., Leyva-Diaz, E., Rahman, M., Sural, S., Attner, M. A., Hobert, O.
10.1101/2025.08.13.670029 — Posted: 2025-11-10
Canonical transcription termination mechanisms explain a minority of operons in cyanobacteria
Cascino, J. A., Dierksheide, K. J., Vishwakarma, R. K., Yuzenkova, Y., Babitzke, P., Murakami, K., Li, G.-W.
10.1101/2025.11.10.687660 — Posted: 2025-11-10
Mus Musculus papillomavirus MmuPV1 resists restriction by human APOBEC3B
Liu, X., Bilger, A., Lee, D., Argyris, P., Chen, J., Ward-Shaw, E., Barreto Duran, E., Lin, Y.-H., Durfee, C., Chun, S. H., Ibrahim, M., Proehl, J., Allen, Y., Lambert, P. F., Harris, R. S.
10.1101/2025.11.10.687577 — Posted: 2025-11-10
Virus induced transgene- and tissue-culture free heritable genome editing in tomato
Jacobsen, S. E., Liu, Y., Weiss, T., Lee, J., Powell, J., Choo, S. Y. C., Roshannai, E., Kamalu, M., Amerasekera, J., Feng, S.
10.1101/2025.11.08.687402 — Posted: 2025-11-09
Parkinsons disease modeling in regenerative spiny mice (Acomys dimidiatus) captures key disease-relevant behavioral, histological, and molecular signatures
Dutta, S., Pang, M., Donahue, R. R., Chou, T.-F., Seifert, A. W., Gradinaru, V.
10.1101/2025.11.06.687049 — Posted: 2025-11-08

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