Channel:  The Howard Hughes Medical Institute (HHMI)

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The mycomembrane proteins PorH and ProtX are inserted at polar growth zones and linked to the cell wall
Hart, E. M., de Bruin, D. A., Marando, V. M., Alemany, M. A., Snow, E. D., Schultz, B. J., Kuru, E., Walker, S., Vettiger, A., Bernhardt, T. G.
10.1101/2025.10.14.682376 — Posted: 2025-10-14
Mapping cellular targets of covalent cancer drugs in the entire mammalian body
Pang, Z., Leung, V. H., Wang, C. C., Attarpour, A., Rinaldi, A., Shen, H., Moya-Garzon, M. D., Sigua, L. H., Rammel, C., Selke, A., Glynn, C., Yender, M., Xu, S., Moslehi, J. J., Wu, P., Long, J. Z., Goubran, M., Cravatt, B. F., Ye, L.
10.1101/2025.03.28.645991 — Posted: 2025-10-14
The complete genome of a songbird
Formenti, G., Jain, N., Medico, J. A., Sollitto, M., Antipov, D., Balacco, J., Barcellos, S., Biegler, M. T., Borges, I., Chang, J. K., Chen, Y., Cheng, H., Conceicao, H. B., Davenport, M., De Oliveira, L. C., Duarte, E., Durham, G. P., Fenn, J., Forde, N., Kim, J., Komissarov, A., Koo, B., Koren, S., Galante, P. A. F., Gerhardt, K., Giani, A. M., Giunta, S., Larkin, D., Lee, C., Li, H., Makova, K., Masterson, P., Murphy, T., McCaffrey, K., Mercuri, R. L. V., Na, Y., O Connell, M. J., Ou, S., Phillippy, A. M., Popova, M., Rhie, A., Ruiz-Ruano, F. J., Secomandi, S., Smeds, L., Suh, A., Tilley
10.1101/2025.10.14.682431 — Posted: 2025-10-14
Transcriptional targets of SPEECHLESS and FAMA control guard cell division and expansion in the late stomatal lineage
Gonzalez-Suarez, P., Hilbers, Y., Budrys, A., Liu, A., Richter, S., Bergmann, D. C., Smit, M. E.
10.1101/2025.10.12.681868 — Posted: 2025-10-14
Ecological cues orchestrate concerted courtship in a Drosophila host specialist
Brand, P., Keller, K., Coleman, R. T., Eghbali, N. B., Zylka, S., Prieto-Godino, L. L., Ruta, V.
10.1101/2025.10.13.681913 — Posted: 2025-10-14
Geometric Tuning of Cytokine Receptor Association Modulates Synthetic Agonist Signaling
Exposit, M., Abedi, M., Krishnakumar, A., Jain, S., Yu, T.-Y., Hercus, T. R., Mathew, D., Gray-Gaillard, S., Chen, Z., Grubbe, W. S., Favor, A., Kan, W. L., Schlichthaerle, T., Chen, W., Parker, M. W., Mendoza, J. L., Lopez, A. F., Wherry, E. J., Baker, D.
10.1101/2025.10.12.681819 — Posted: 2025-10-13
Multiplex design and discovery of proximity handles for programmable proteome editing
Suiter, C. C., Ahn, G., Chiu, M., Fu, Y., Sadre, S., Simon, J. J., Lee, D. S., Fowler, D. M., Maly, D. J., Baker, D., Shendure, J.
10.1101/2025.10.13.681693 — Posted: 2025-10-13
Rapid development and field evaluation of a portable CRISPR-based assay for Mpox during the 2025 Sierra Leone outbreak
Gopal, N., Abay, T., Payne, C., Gomez, M., Fofanah, I. U., Rogers, M. M., Kallon, T. P., Kamara, M. S., Suk, H.-J., Sandi, J. D., Brock-Fisher, T., Stachler, E., Allan-Blitz, L.-T., Roach, D. J., Paye, M. F., Wilkason, C., Grant, D. S., Ozonoff, A., Sabeti, P. C.
10.1101/2025.10.08.25337506 — Posted: 2025-10-13
High-Throughput De Novo Protein Design Yields Novel Immunomodulatory Agonists
Abedi, M., Exposit, M., Coventry, B., Mathew, D., Jain, S., Krishnakumar, A., Goreshnik, I., Gray-Gaillard, S., Lunn-Halbert, M., Yu, T.-Y., Glögl, M., Mitchell, U., Keshri, R., Chun, J. H., Ruohola-Baker, H., Wherry, E. J., Baker, D.
10.1101/2025.10.12.681920 — Posted: 2025-10-13
Direct cell reprogramming by a designed agonist inducing HER2-FGFR proximity
Keshri, R., Exposit, M., Abedi, M., R Hicks, D., Foreman, Z., Phal, A., Lim, Y. C., Barrett, P., Sniezek, C., Lin, J., Schlichthaerle, T., J Robinson, A., Detraux, D., Ching, T. C., Wu, K., Coventry, B., Chang, L., S.T. Smith, A., L Mack, D., K Schweppe, D., Martin, B. E., Hristova, K., Mathieu, J., Baker, D., Ruohola-Baker, H.
10.1101/2025.10.12.681903 — Posted: 2025-10-13

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