Channel:  The Howard Hughes Medical Institute (HHMI)

1,958 Articles

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In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
Basiashvili, T., Hutchings, J., Chen, S., Karasmanis, E. P., Flaherty, W. A., Leschziner, A. E., Villa, E.
10.64898/2025.12.18.694444 — Posted: 2025-12-19
Characterizing the informativeness of pathogen genome sequence datasets about transmission between population groups
Tran-Kiem, C., Perofsky, A. C., Lessler, J., Bedford, T.
10.1101/2025.08.07.25333239 — Posted: 2025-12-18
Human acrocentric chromosome short arm de novo mutation and recombination
Lin, J., Mastrorosa, F. K., Noyes, M. D., Yoo, D., Rhie, A., Porubsky, D., Hoekzema, K., Munson, K. M., Koundinya, N., Watkins, W. S., Jorde, L. B., Quinlan, A. R., Neklason, D. W., Phillippy, A. M., Eichler, E. E.
10.64898/2025.12.16.694519 — Posted: 2025-12-17
Spatial gene expression maps in vertebrate limbs display conserved and regenerative species-specific features within connective tissue
McMann, C. L., Park, C., Cloutier, J. K., Reddien, P.
10.64898/2025.12.15.694399 — Posted: 2025-12-17
Antibody Mediated Diversification of Primary and Secondary Immune Responses
Schaefer-Babajew, D., Binet, L., Santos, G. S. S., Ruprecht, C., Deimel, L. P., ElTanbouly, M. A., Gharrassi, D., Uhe, C., Yao, K.-H., Hernandez, B., Agrawal, P., Gazumyan, A., Stamatatos, L., Hartweger, H., Nussenzweig, M. C.
10.64898/2025.12.15.694384 — Posted: 2025-12-17
Humanized Extracellular Vesicles for Efficient RNA Delivery
Ma, X., Zhao, S. R., Cepko, C. L.
10.64898/2025.12.15.694436 — Posted: 2025-12-17
Nanopore-based profiling of PEGylation in nucleic acid therapeutics
Patino Guillen, G., Schmidt, T. T., Baumberg, J. J., Szostak, J. W., Keyser, U. F., Boskovic, F.
10.64898/2025.12.15.694309 — Posted: 2025-12-17
Mitochondria-derived PEP licenses glycerolipid synthesis via SLC25A35
Yamamuro, T., Katoh, D., Silva, G. M., Nishida, H., Oikawa, S., Higuchi, Y., Wang, D., Fujimoto, M., Yoshida, N., Li, M., Shin, J., Zhao, Z., Yook, J.-S., Sun, L., Kajimura, S.
10.64898/2025.12.12.693842 — Posted: 2025-12-16
The Drosophila maternal-effect gene abnormal oocyte (ao) does not repress histone gene expression
Takenaka, R., Albanese, E. H., Simmerman, S. M., Verghese, S., Maddox, M. A. E., de la Cruz, A., Young, J. M., Schmidt, C. A., Rieder, L. E., Malik, H. S.
10.1101/2024.09.17.613536 — Posted: 2025-12-16
A signature-agnostic test for differences between tumor mutation spectra reveals carcinogen and ancestry effects
Hart, S. F. M., Alcala, N., Feder, A. F., Harris, K.
10.1101/2025.05.15.654154 — Posted: 2025-12-16

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