Channel:  The Howard Hughes Medical Institute (HHMI)

1,892 Articles

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Lipid bilayer thinning near a ubiquitin ligase selects ER membrane proteins for degradation
Pisa, R., Rapoport, T. A.
10.1101/2025.10.31.685944 — Posted: 2025-11-01
B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes
Zhou, P., Hartweger, H., MacLean, A. J., Ramos, V., Yao, K.-h., Hernandez, B., Wang, Z., Gazumyan, A., Nussenzweig, M. C.
10.1101/2025.10.30.685663 — Posted: 2025-11-01
Co-opting the bacterial lipoprotein pathway in the biosynthesis of a lipidated macrocyclic peptide
Chen, J. Y., Zhu, L., Zhang, K. Y., Berthold, D. A., van der Donk, W. A.
10.1101/2025.10.31.685832 — Posted: 2025-11-01
Adapting CRISPR-associated transposons for rapid and high-throughput reverse genetics
Basta, D. W., Zingl, F. G., Yang, Y., Nguyen, K. T., Liu, Y.-Y., Waldor, M. K.
10.1101/2025.10.31.685825 — Posted: 2025-11-01
De novo design of metal-oxide templating proteins
Saragovi, A., Pyles, H., Huddy, T. F., Li, X., Borst, A. J., Hanikel, N., Courbet, A., Kwon, P., Davila-Hernandez, F. A., Kibler, R. D., Vafeados, D. K., Allen, A., Carr, K. D., Bera, A., Kang, A., Brackenbrough, E., Schmid, S., Bae, Y., Stewart, L., Zhang, S., De Yoreo, J., Baker, D.
10.1101/2024.06.24.600095 — Posted: 2025-11-01
Specialized parallel pathways for adaptive control of visual object pursuit
Collie, M. F., Jin, C., Rockwell, V., Kellogg, E., Vanerbeck, Q. X., Hartman, A. K., Holtz, S. L., Wilson, R. I.
10.1101/2025.04.23.650240 — Posted: 2025-11-01
Phage display-mediated immuno-PCR to detect low-abundance secreted proteins in Drosophila
Han, M., Xia, B., Kim, A.-R., Filine, E., Stoneburner, E., Miao, T., Liu, Y., Zirin, J., Perrimon, N.
10.1101/2025.10.31.685841 — Posted: 2025-10-31
Microbial-inspired antidotes to repurpose toxic compounds as antibiotics
Samad, T. S., Ngambenjawong, C., Ko, H., Patel, S., DeAgazio, C., Fleming, H. E., Bhatia, S. N.
10.1101/2025.10.31.685078 — Posted: 2025-10-31
Sleep-dependent clearance of brain lipids by peripheral blood cells
Cho, B., Youngstrom, D. E., Killiany, S., Guevara, C., Randolph, C. E., Beveridge, C. H., Saklani, P., Chopra, G., Sehgal, A.
10.1101/2025.10.30.685668 — Posted: 2025-10-31
larch: mapping the parsimony-optimal landscape of trees for directed exploration
Barker, M., Milanov, O., Dumm, W., Rich, D., Turakhia, Y., Matsen, F. A.
10.1101/2025.10.29.685337 — Posted: 2025-10-31

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