Channel:  The Howard Hughes Medical Institute (HHMI)

1,947 Articles

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miRNA modules for precise, tunable control of gene expression
Du, R., Flynn, M. J., Mahe, K., Honsa, M., Gu, B., Li, D., McGeary, S. E., Gradinaru, V., Jungmann, R., Elowitz, M. B.
10.1101/2024.03.12.583048 — Posted: 2025-12-02
Need-selective gating of dopamine neuron cue responses by real and virtual hunger
Mamaligas, A. A., Berke, J., Kreitzer, A. C., Knight, Z. A.
10.64898/2025.11.29.691326 — Posted: 2025-12-02
Sleep controls peroxisomal abundance to reduce wake-induced brain oxidation
Guevara, C., Li, Y., Pyfrom, E. S., Killiany, S., Yue, Z., Sehgal, A.
10.1101/2025.11.28.691144 — Posted: 2025-12-01
Naegleria amoebae seek confinement and crawl persistently through narrow spaces
Velle, K., Ramaswamy, M., Hokmabad, B. V., Martin-Perez, T., Carrasco, T. T., Callahan, W. S., Kim, H. S., Datta, S. S., Edwards, M., Fritz-Laylin, L.
10.1101/2025.11.30.691445 — Posted: 2025-12-01
Molecular interplay between the DNA damage checkpoint kinase Mec1-Ddc2 and its activator Dpb11 on gapped DNA
Beckwitt, E. C., Chua, G. N. L., Liu, S., O'Donnell, M. E.
10.1101/2025.11.28.691181 — Posted: 2025-11-30
Orthosteric Molecular Glue Inhibits COP9 Signalosome with Substrate-Dependent Potency
Shi, H., Wang, X., Yu, C., Mao, H., Jiao, F., Braitbard, M., Shor, B., Zhang, Z., Hinds, T. R., Cao, S., Fan, E., Schneidman-Duhovny, D., Huang, L., Zheng, N.
10.1101/2025.11.26.690573 — Posted: 2025-11-30
Early-life stromal niches orchestrate B lymphopoiesis at the brain's borders
Walker, A. J., Fisher, T. M., Caldwell, S. K., Gupte, A. S., Colville-Reimertz, J. M., Sabikunnahar, B., Marsh, S. E., de Soysa, Y., Gazestani, V. H., Walker, A. C., Huang, Y., Mavinkurve, A. V., Barr, H. J., Lanser, T. B., Murphy, S., Bowling, S., Dissing-Olesen, L., Camargo, F. D., Stevens, B.
10.1101/2025.11.27.690844 — Posted: 2025-11-29
Ultrafast CTCF dynamics control cohesin barrier function
Rudnizky, S., Murray, P. J., Sorensen, E. W., Koenig, T. J. R., Pangeni, S., Merino-Urteaga, R., Chhabra, H., Caccianini, L., Davidson, I. F., Osorio-Valeriano, M., Hook, P. W., Meneses, P., Hao, J., Zarb, J. S., Hatzakis, N. S., Timp, W., Farnung, L., Vos, S. M., Peters, J.-M., Aksimentiev, A., Ha, T.
10.1101/2025.11.25.690553 — Posted: 2025-11-29
A lateralized pathway for associating nutrients with flavors
Grove, J. C. R., Hakimi, A. M., Li, Q., Zhang, J., Backes, H., Kuzmanovic, B., Choi, J., Ubadiah, V., Qiu, L., Liu, Z., Small, D. M., Tittgemeyer, M., Knight, Z. A.
10.1101/2025.02.09.637334 — Posted: 2025-11-28
Long-range mRNA folding shapes expression and sequence of bacterial genes
Gill, M. S., Kim, I. A., Xue, J. R., Thappeta, Y., Taggart, J. C., Li, G.-W.
10.1101/2025.11.27.690947 — Posted: 2025-11-27

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