Channel:  The Howard Hughes Medical Institute (HHMI)

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De Novo Design of Miniprotein Inhibitors of Bacterial Adhesins
Chazin-Gray, A. M., Thompson, T. R., Lopatto, E. D. B., Magala, P., Erickson, P. W., Hunt, A. C., Manchenko, A., Aprikian, P., Tchesnokova, V., Basova, I., Sanick, D. A., Tamadonfar, K. O., Timm, M. R., Pinkner, J. S., Dodson, K. W., Kang, A., Joyce, E., Bera, A. K., Schmitz, A. J., Ellebedy, A. H., Hvorecny, K. L., Interlandi, G., Cartwright, M. J., Vernet, A., Bardales, S., White, D., Klevit, R. E., Sokurenko, E. V., Hultgren, S. J., Baker, D.
10.1101/2025.08.18.670751 — Posted: 2026-09-16
Whole-body 3D kinematics of freely behaving Drosophila
Ispizua, J. I., Abe, E. T. T., Yan, J., Othayoth, R., Sawtelle, S., Atkins, F., Shiozaki, H., Meier, N. R., Wong, J., Tran, T. T., Mori, C. K., Chen, W., Voigts, J., Stern, D. L., Brunton, B. W., Tuthill, J. C., Johnson, R. E.
10.64898/2026.05.03.722293 — Posted: 2026-09-16
ACAD10 encodes two orphan enzymes in the ether lipid biosynthetic and salvage pathways
Ye, J., Purlyte, E., Lopez, V. A., Mill, J., Tatge, L., Kizzar, T., Baldwin, D., Rashan, E., Kim, J., Pagliarini, D. A., Tomchick, D. R., Pawlowski, K., Douglas, P., Simcox, J., Tagliabracci, V. S.
10.1101/2025.09.10.675409 — Posted: 2026-09-15
A rational design strategy and validation for protease-resistant fusion-inhibitor antiviral peptides
Yang, K., Wang, C., Topi, F., Muratcioglu, S., Kant, R., Strandin, T., Bong, Y. T., Kareinen, L., Mäki, S., Saber, S. H., Binder, T., Sironen, T., Subramanian, S., White, K. I., Pfuetzner, R., Esquivies, L., Vapalahti, O., Joensuu, M., Kuriyan, J., Hepojoki, J., Balistreri, G., Brunger, A. T.
10.64898/2026.09.12.750390 — Posted: 2026-09-15
Human genetics implicates a BACH2-NRF2 axis in fetal hemoglobin activation
Guo, C.-J., Arora, U. P., Xu, W., Cheng, X., Cato, L. D., Li, R., Lu, H. Y., Lee, A. J., Yu, F., Agarwal, G., Lyu, P., Ye, T., Antoszewski, M., Wissman, M., Mkumbe, B. S., Ekwattanakit, S., Deelen, P., Mwita, L., Sangeda, R. Z., Suksangpleng, T., Riolueang, S., Bronson, P. G., Paul, D. S., Kawabata, E., Astle, W. J., Aguet, F., Ardlie, K., Lopez de Lapuente Portilla, A., Kang, G., Zhang, Y., Nouraie, S. M., Gordeuk, V. R., Gladwin, M. T., Garrett, M. E., Ashley-Koch, A., Telen, M. J., Custer, B., Kelly, S., DINARDO, C., Sabino, E. C., Loureiro, P., Carneiro-Proietti, A. B., Maximo, C., Mendez
10.1101/2023.03.24.23287659 — Posted: 2026-09-15
Mechanisms of mucosal immunity to oral Shigella infection in a physiological mouse model
Babirye, J. P., Lackner, E. F., Yuvaraj, S., Chavez, R. A., Nichols, C. A., Eislmayr, K. D., Fattinger, S. A., Kotov, D. I., lesser, c., Vance, R.
10.64898/2026.09.08.750193 — Posted: 2026-09-14
Enhancer Tuning by Sequence-Specific Repressors
Ichino, L., Brennan, K. J., Mallory, B. J., Swigut, T., Bohaczuk, S. C., Mohammed, J., Mudeppa, D. G., Tabatabaee, S., Ni, C., Stergachis, A. B., Wysocka, J.
10.64898/2026.09.11.751074 — Posted: 2026-09-14
MEF-2 repression of GEM-4/Copine expression decreases muscle excitability by increasing gap junction coupling
Gao, L., Pym, E., Nurrish, S., Kaplan, J. M.
10.64898/2026.04.09.717484 — Posted: 2026-09-14
Loss of LanC-like proteins impairs post-injury regeneration of aging muscles
Reyes-Ordonez, A., Zhou, T. H., Rao, T. C., Barai, P., van der Donk, W. A., Chen, J.
10.64898/2026.05.15.725287 — Posted: 2026-09-14
Substrate Binding Relieves Autoinhibition of the Mammalian GCN2 Kinase
Catipovic, M. A., Green, R.
10.64898/2026.09.09.750423 — Posted: 2026-09-13

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