Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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Multimodal profiling of proinflammatory protease activity identifies caspase-1 as a target for lung cancer interception
Wang, C. S., Zhong, Q., Wang, S.-T., Alonso, M. C. M., Neaher, S., Patel, S., Parisi, T., Kirkpatrick, J. D., Sequist, L. V., Jacks, T. E., Bhatia, S.
10.1101/2025.07.01.662195 — Posted: 2025-07-02
Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503
LaVigne, C. A., Han, J., Zhang, H., Cho, S., Kim, M., Sethia, K., Evers, B. M., Acharya, A., Chang, T.-C., Mendell, J. T.
10.1101/2025.06.30.662380 — Posted: 2025-07-01
Ligand-induced ubiquitination regulates endocytosis and homeostasis of the ERECTA receptor kinase for stomatal development
Chen, L., Vu, M. H., Cochran, A. M., Ying, C. F., Torii, K. U.
10.1101/2025.06.29.662054 — Posted: 2025-07-01
SNARE disassembly requires Sec18/NSF side-loading
Khan, Y. A., White, K. I., Pfuetzner, R. A., Singal, B., Esquivies, L., Mckenzie, G., Liu, F., DeLong, K., Choi, U. B., Montabana, E., Mclaughlin, T., Wickner, W. T., Brunger, A. T.
10.1101/2024.08.30.610324 — Posted: 2025-06-30
OocystMeter, a machine-learning algorithm to count and measure Plasmodium oocysts, reveals clustering patterns in the Anopheles midgut
Peng, D., Marrogi, E., Nelson, E., Liu, Q., Rinvee, T. A., de Vries, L. E., Thornburg, K., Singh, N., Shaw, W. R., Catteruccia, F.
10.1101/2025.06.28.662088 — Posted: 2025-06-29
Histone diversity in the archaeal domain of life
Laursen, S. p., Luger, K.
10.1101/2025.06.26.661778 — Posted: 2025-06-27
Prioritizing replay when future goals are unknown
Sagiv, Y., Akam, T., Witten, I., Daw, N. D.
10.1101/2024.02.29.582822 — Posted: 2025-06-27
A cell-based scrambling assay reveals phospholipid headgroup preference of TMEM16F on the plasma membrane
Teo, C. F., Tuomivaara, S. T., van Hilten, N., Crottes, D., Jan, Y. N., Grabe, M., Jan, L. Y.
10.1101/2025.06.25.661602 — Posted: 2025-06-27
Early transcriptional signatures of MeCP2 positive and negative cells in Rett syndrome
Li, Y., Anderson, A. G., Qi, G., Wu, S.-R., Revelli, J.-P., Liu, Z., Zoghbi, H. Y.
10.1101/2025.06.26.661761 — Posted: 2025-06-26
Direct observation of interdependent and hierarchical kinetochore assembly on individual centromeres
Hu, C., Popchock, A. R., Latino, A. A., Asbury, C. L., Biggins, S.
10.1101/2025.06.25.661565 — Posted: 2025-06-26

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