Channel:  The Howard Hughes Medical Institute (HHMI)

1,907 Articles

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Massively parallel reporter assay for mapping gene-specific regulatory regions at single nucleotide resolution
Tulloch, A. J., Delgado, R. N., Catta-Preta, R., Cepko, C. L.
10.1101/2025.05.13.653746 — Posted: 2025-11-14
FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity
Ladewig, E., Nazir, A., Park, T., Fan, V. B., Cao, Z., Hawk, J., Kelly, L., Tjian, R., Leslie, C. S., Sawyers, C.
10.1101/2025.11.13.688263 — Posted: 2025-11-14
Evolutionary basis of intermale sexual behavior by multiple pheromone switches in Drosophila
Ouadah, Y., Naragon, T. H., Smihula, H., Behrman, E. L., Khallaf, M. A., Ding, Y., Stern, D. L., Parker, J., Anderson, D. J.
10.1101/2025.10.14.682417 — Posted: 2025-11-14
Modulating MyoD1 dosage activates alternate cell fate beyond myogenic differentiation
Whitney, O. N., Dailey, G. M., McKenna, J. K., Darzacq, X., Tjian, R.
10.1101/2025.11.13.688391 — Posted: 2025-11-14
Extracting task-relevant preserved dynamics from contrastive aligned neural recordings
Jiang, Y., Sheng, K., Gao, Y., Buchanan, E. K., Shikano, Y., Kim, T. H., Zhao, Y., Woo, S. J., Dinc, F., Linderman, S. W., Schnitzer, M. J.
10.1101/2025.11.11.686428 — Posted: 2025-11-13
Cap1 forms a cyclic tetra-adenylate-induced membrane pore during the type III-A CRISPR-Cas immune response
Majumder, P., Cahir, C. W., Roberts, C. G., Patel, D. J., Marraffini, L. A.
10.1101/2025.11.13.688252 — Posted: 2025-11-13
The G3BP stress-granule proteins reinforce the integrated-stress-response translation program
Smith, J., Bartel, D. P.
10.1101/2024.10.04.616305 — Posted: 2025-11-13
Uncovering the molecular basis of kinase activity and substrate recognition with phospho-PCA
Yu, C., Pao, E., Van Valen, D. A.
10.1101/2025.11.07.687244 — Posted: 2025-11-13
Expression of four mitochondrial tRNAs from only two loci
Warren, J. M., Prasad, K. V. S. K., Mendez, A. M., Temnyk, S., McCutcheon, J.
10.1101/2025.11.12.688142 — Posted: 2025-11-13
Proteome-wide in silico screening for human protein-protein interactions
Schmid, E., Zhu, H., Ryu, E., Lim, Y., Smogorzewska, A., Brown, A., Walter, J.
10.1101/2025.11.10.687652 — Posted: 2025-11-12

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