Channel:  The Howard Hughes Medical Institute (HHMI)

1,953 Articles

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Reconstructing a physiological state space via chronic jugular microdialysis in freely moving mice
Nardin, M., Wang, N., Elziny, S., Boyer, C., Pjanovic, V., Schuster, L., Boklund, P., Lindo, S., Morris, K., Ilanges, A., Voigts, J., Dennis, E. J.
10.64898/2025.12.08.692974 — Posted: 2025-12-11
Drosophila maintain a consistent navigational goal angle for days to weeks
Weisman, J. L., Mohren, T. L., Ryu, J. D., Wyse, M. Z., Dias-Ferreira, E., Maimon, G.
10.64898/2025.12.09.693277 — Posted: 2025-12-11
A shared DNA-repeat toxicity threshold, reached somatically at cell-type-specific rates, unites cortical and striatal neurodegeneration in Huntingtons disease
Kashin, S., Lee, W.-S., McDonald, T. M., Morris, K., Handsaker, R. E., Mello, C., Spina, L., Reed, N. M., de Rivera, H., Jana, S. H., Hogan, M., Berretta, S., McCarroll, S. A.
10.64898/2025.12.09.688862 — Posted: 2025-12-11
The circadian clock regulates scavenging of fluid-borne substrates by brain border-associated macrophages
Barr, H. J., Caldwell, S. K., Reimertz, J. M., Depp, C., Walker, A. J., Marsh, S. E., Gupte, A. S., Hingerl, M., Patel, J., Park, S.-O., Ferraro, S., Lipton, J., Stevens, B.
10.64898/2025.12.08.693074 — Posted: 2025-12-11
Design of Orthogonal Far-Red, Orange and Green Fluorophore-binding Proteins for Multiplex Imaging
Tran, L., Klein, S., Sharma, S., Juergens, D., Decarreau, J., Liu, B., Wang, Y., Bera, A. K., Kang, A., Woods, J., Joyce, E., Vafeados, D. K., Roullier, N., Chen, W., Lee, G. R., Lavis, L. D., Mahamid, J., An, L., Baker, D.
10.1101/2025.08.03.668343 — Posted: 2025-12-10
Structural basis of stepwise G protein activation by a viral chemokine receptor
Jude, K. M., Suomivuori, C.-M., Waghray, D., Maeda, S., Fujiyoshi, Y., Inoue, A., Garcia, K. C., Tsutsumi, N.
10.64898/2025.12.10.692789 — Posted: 2025-12-10
Multimodal cell lineage reconstruction in the hindbrain reveals a link between progenitor origin and activity patterning
Blanc, M., Meister, L., Lemon, W. C., Fiuza, U.-M., Keller, P. J., Espinosa-Medina, I., Pujades, C.
10.1101/2025.11.14.688499 — Posted: 2025-12-09
Modeling tissue-specific Drosophila metabolism identifies high sugar diet-induced metabolic dysregulation in muscle at reaction and pathway levels
Moon, S. J., Hu, Y., Dzieciatkowska, M., Kim, A.-R., Asara, J. M., D'Alessandro, A., Perrimon, N.
10.1101/2024.04.24.591006 — Posted: 2025-12-09
The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome
Shen, B. A., Asfahl, K. L., Lim, B., Bertolli, S. K., Minot, S. S., Radey, M. C., Penewit, K., Ngo, B., Salipante, S. J., Johnston, C. D., Peterson, S. B., Goodman, A. L., Mougous, J. D.
10.1101/2025.11.29.690828 — Posted: 2025-12-08
Brain-immune interactions generate pathogen-specific sickness states
Sullivan, Z. A., Wong, B. J., Kapoor, V., Vincze, P. K., Kaplan, H. S., Giraudet, P., Watson, B. R., Misherghi, A., Lourido, S., Moffitt, J. R., Dulac, C.
10.64898/2025.12.06.692770 — Posted: 2025-12-08

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