Channel:  The Howard Hughes Medical Institute (HHMI)

2,311 Articles

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Actin disassembly triggers CNS myelin compaction and wrapping
Kantarci, H., Wu, K., Ambiel, N., Chaparro Barriera, E., Cooper, M. H., Münch, A., Sigal, Y. M., Garcia, M. A., Iyer, M., Jorgens, D. M., Zuchero, J. B.
10.64898/2026.05.14.722739 — Posted: 2026-05-15
Structure and Mechanism of a Two-component Lanthipeptide Toxin
Moreira, R., Giurgiu, C., Rahman, I. R., Patterson, M., Huber, S. T., Yang, Y., Jeanne Dit Fouque, K., Fernandez-Lima, F., Liu, G., Guo, R., Kelich, P., Wen, P.-C., Tajkhorshid, E., Johnson, A. G., van der Donk, W. A.
10.64898/2026.05.13.724966 — Posted: 2026-05-14
WATER reveals heterochrony of molecular programs underlies developmental failure caused by minor spliceosome inhibition
Springer, S. M., Boria, A. R., Drake, K. D., Afriyie, K. O., Girardini, K. N., Konakanchi, T., Stevens, I., Camacho, N., Lopes, T., Kanadia, R. N.
10.64898/2026.05.08.723603 — Posted: 2026-05-13
Promoter strength and position govern promoter competition via transcript-dependent insulation
Koska, M., Nagano, M., Swigut, T., Boettiger, A. N., Hansen, A. S., Wysocka, J.
10.1101/2025.05.06.652547 — Posted: 2026-05-13
Spatial distribution of blood-brain barrier membrane proteins is controlled by sorting motifs and physiological signals in vivo
Amick, J., Bhandarkar, S., Wilcox, D. R., Boloker, S., Gu, C.
10.64898/2026.05.10.724157 — Posted: 2026-05-13
δ-catenin controls layer-specific transcriptional maturation of astrocytes via Zbtb20
Sejourne, G., Tan, C. X., Savage, J. T., Manigault, G., Richardson, G., Ding, J., Hardin, E. J., Ramirez, J., Baumert, R., Sakers, K., Eroglu, C.
10.64898/2026.05.12.724361 — Posted: 2026-05-13
First Lithic Age Caribbean genomes document pre-Ceramic genetic continuity and affinities to Central America and northern South America
Sirak, K., Lopez Belando, A. J., Shelley, D., Arevalo, M. G., Shelley, D., Mallick, S., Rohland, N., Reich, D. E.
10.64898/2026.05.12.724636 — Posted: 2026-05-13
Targeting an RNA Editor to Impede H3K27M+ Pediatric Gliomas
Ramsoomair, C. K., Alvarez, V., Sarmiento, F., Aramburu Berckemeyer, M., Seetharam, D., Kalliecharan, K., Moorkkannur, S. N., Mitchell, J., Hudson, A., Taylor, J., Ceccarelli, M., Bayik, D., Becher, O. J., Prabahakar, R., Welford, S., Gampel, B., De Carvalho, D. D., Reinberg, D., Shah, A. H.
10.64898/2026.05.08.723800 — Posted: 2026-05-12
Replaying germinal center evolution on a quantified affinity landscape
DeWitt, W. S. S., Vora, A. A., Araki, T., Galloway, J. G., Alkutkar, T., Bortolatto, J., Castro, T. B., Dumm, W., Jennings-Schaffer, C., Jia, T., Mesin, L., Ozorowski, G., Pae, J., Ralph, D. K., Bloom, J. D., Nourmohammad, A., Song, Y. S., Ward, A., Starr, T. N., Matsen, F. A., Victora, G. D.
10.1101/2025.06.02.656870 — Posted: 2026-05-12
The transcriptional and translational outcomes for pseudogenes in bacterial endosymbionts
Garber, A., Nwachukwu, J., Stikeleather, R., York, C., McCutcheon, J.
10.64898/2026.02.04.703838 — Posted: 2026-05-12

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