Channel:  The Howard Hughes Medical Institute (HHMI)

2,693 Articles

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Dystrophic changes of nigrostriatal axons harboring a Synj1 Parkinson mutation suggest catastrophic failure of endocytic mechanisms
Wu, Y., Xu, P., Moran, J., Xu, C. S., Hayworth, K., Cao, M., Shao, L., Surmeier, D. J., Hess, H., De Camilli, P.
10.64898/2026.06.24.733515 — Posted: 2026-09-10
AAV-DJ Enables Targeted Gene Modulation in Human Ovarian Cells
Salpeter, N., Gokyer, D., Hemis, B., Wu, A. K., Tsui, E. L., Saunders, D. C., Lohman, M., Kleinhans, A., Riley, J., Laronda, M. M., Adli, M., Gradinaru, V., Borsos, M., Babayev, E.
10.64898/2026.09.08.749939 — Posted: 2026-09-10
Pan-neutralization of parainfluenza viruses by a hemagglutinin-neuraminidase antibody
De Marco, A., Gen, R., Park, Y.-J., Cusumano, G., Gibson, C., Vyas, S., Momont, C., Tasin, F., Galli, S. C., Merz, B., Giacchetto-Sasselli, I., Vetti, E., Reitz, T., Tsu, B., Yim, K., Blanco, J., Piantanida, R., Czudnochowski, N., Miller, J. L., Snell, G., Boukhvalova, M. S., Towne, J. E., Corti, D., Pizzuto, M. S., Veesler, D.
10.64898/2026.09.07.749649 — Posted: 2026-09-10
AAV delivered lysosome-targeting chimeras mediate sustained antibody depletion in vivo
Yang, J. L., Loh, K. Y., Sandoval Espinoza, C. R., Schuster, D., Yamada-Hunter, S. A., Labanieh, L., Sotillo, E., Mackall, C., Deisseroth, K., Bertozzi, C.
10.64898/2026.07.05.736665 — Posted: 2026-09-10
Dissociation kinetics and avidity gate SARS-CoV-2 neutralization by HR2 stem helix antibodies
Crivelli, V., Guerra, C., Abernathy, M. E., Sgrignani, J., Zoppi, G., Greeson, M. L., Sanga, A., Locatelli, P., Cantergiani, J., Cena, B., Cervantes Rincon, T., Lee, Y. E., Eso, M., Jarrossay, D., Biggiogero, M., Calvaruso, V., Franzetti Pellanda, A., Garzoni, C., Tamagnini, E., Lestani, S., Varani, L., Sommer, S., Fernandez, D., Barba Spaeth, G., Niejadlik, E. G., Bournazos, S., Robbiani, D. F., Barnes, C. O., Cavalli, A.
10.64898/2026.08.17.745160 — Posted: 2026-09-09
A Synthetic Archaeal Lipid Analog Enables Quantification of Substrate, Products, and Intermediates in the Tetraether Synthase Reaction
Lloyd, C., Wang, B., Booker, S.
10.64898/2026.09.04.749484 — Posted: 2026-09-09
RFOptimization: Guiding Design Optimization with All-Atom Structure Prediction
Zhang, O., Wang, J., Thompson, T. R., You, Z., Song, Z., DiMaio, F., Baker, D.
10.64898/2026.09.04.749184 — Posted: 2026-09-09
Oral Actinobacteria sense and defend against parasitic epibionts
Wang, Y., Colautti, J., Gallagher, L. A., Lee, J., Tan, Y., Farrell, S., Farrell, C., Bor, B., Whitney, J. C., Zhang, D., Peterson, S. B., Mougous, J. D.
10.64898/2026.09.08.750141 — Posted: 2026-09-09
Interleukin-1 receptor antagonist is a conserved factor for exacerbating tuberculosis susceptibility
Lee, O. V., Pathak, E., Hernandez-Bazan, S., Ji, D. X., Rosa, B. A., Jaye, D. L., Suliman, S., Mitreva, M., Gabay, C., Vance, R. E., Kotov, D. I.
10.1101/2023.10.27.564420 — Posted: 2026-09-09
Terminal selector and subtype selector function across 200 million years of nematode evolution
Ramadan, Y., Loer, C., Yim, H., Geiger, L. T., Merritt, D. M., Toker, I. A., Evenblij, J., Witte, H., Cook, S. J., Sommer, R. J., Hobert, O.
10.64898/2026.09.04.749377 — Posted: 2026-09-08

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