Channel:  The Howard Hughes Medical Institute (HHMI)

2,393 Articles

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Elevated MyoD1 levels expand genome-wide binding and the repertoire of regulated genes
Whitney, O. N., Dailey, G. M., McKenna, J. K., Darzacq, X., Tjian, R.
10.1101/2025.11.13.688391 — Posted: 2026-06-03
The structural basis for LRRK2's activation and autoinhibition
Villagran Suarez, A., Hatch, K. S., Bodrug, T., Gai, W., Surridge, K. J., Moussikhina, E., Nguyen, K. H., Sanz-Murillo, M., Callahan, R., Xiong, E., Ramos, D., Zhu, L., Dederer, V., Mathea, S., Iwasa, J. H., Knapp, S., Shokat, K., Reck-Peterson, S. L., Leschziner, A. E.
10.64898/2026.05.31.729085 — Posted: 2026-06-03
Chaperones shape the conformational landscape of 26S-proteasome-base assembly for allosteric ATPase motor activation
Martin, A., Hsieh, H.-H.
10.64898/2026.06.01.729410 — Posted: 2026-06-02
Atomic layer deposition for core-shell microparticle vaccines enabling programmable antigen delivery to lymph nodes enhance humoral immune responses
Chaudhary, N., Coleman, H. J., Paolone, E. V., Yu, J., Ledbetter, A. W., Lemnios, A. A., Walsh, A. A., Suh, H., Wang, A., Mansoor, M. M., Giancola, J. B., Melo, M. B., Rauch, A. M., Langsfeld, E. S., Parlikar, U. R., Pacheco, M. O., Williams, C. A., Funke, H. H., Garcea, R. L., Randolph, T. W., Irvine, D. J.
10.64898/2026.05.29.728600 — Posted: 2026-06-02
Cholesterol, PtdIns(4,5)P2, and Actin Regulate BK Channel Nanoscale Organization
Pournejati, R., Ma, M., Huang, J. M., de la Cruz, L., Moreno, C. M., Vivas, O.
10.64898/2026.04.20.719652 — Posted: 2026-06-02
Gigabase-scale deletion scanning of the human genome
Koeppel, J., Keith, A., Sgrizzi, S., Chen, P., Daza, R. M., Quaisar, F., Anastasia, E., Song, Z., Shendure, J., Pinglay, S.
10.64898/2026.05.29.728882 — Posted: 2026-06-02
Genetic Diversity and Population Structure of the Black-Footed Cat: Insights into Felis's Deadliest Predator
Grant, V. B., Hunnicutt, K., Schroeder, M., Küsters, M., Oppenheimer, J., Banerjee, S., Baczenas, J. J., Petrov, D., Bishop, J. M., Lamberski, N., Wilson, B., Sliwa, A., Shapiro, B., Solari, K. A., Aguillon, S. M., Armstrong, E. E., Schumer, M.
10.64898/2026.05.29.728895 — Posted: 2026-06-02
Multimodal dynamics control activity of a glial glutamate transporter
Wu, Q., Ciftci, D., Canul Tec, J., Reyes, N., Gregorio, G., Huang, Y., Boudker, O.
10.64898/2026.05.29.728845 — Posted: 2026-06-02
Decoding stage-specific functions of PRC2 uncovers a cell-autonomous role in preimplantation development and a non-cell-autonomous role in primordial germ cell fate
Zhou, C., Wang, M., Chen, Z., Zhang, Y.
10.64898/2026.01.20.700679 — Posted: 2026-06-01
The defining features of intrinsic transcription terminators
Battaglia, R. A., LI, G.-W., Ermis, E., Omollo, E.
10.64898/2026.05.29.728758 — Posted: 2026-05-31

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