Channel:  The Howard Hughes Medical Institute (HHMI)

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Fixed human pangenome sequences reveal origins of common human traits
Goh, C.-s., Davenport, M., Lee, C., Jarvis, E.
10.64898/2026.04.30.722098 — Posted: 2026-05-05
Dynamic Monitoring of Antibody Drug Conjugates Targeting TROP2 or HER2 in Breast Cancer using Circulating Tumor Cells
Mishra, A., Abelman, R., Cunneely, Q., Putaturo, V., Deshpande, A. A., Bell, R., Seider, E. M., Xu, K. H., Shan, M., Kelly, J., Huang, S.-B., Rieur, O., Knape, J., Gopinathan, K. A., Kikkeri, K., Edd, J. F., Walsh, J., Dai, C. S., Ellisen, L., Ting, D. T., Nieman, L., Toner, M., Bardia, A., Haber, D. A., Maheswaran, S.
10.1101/2025.04.02.646822 — Posted: 2026-05-05
PfApiAT2 is a proline transporter essential for the transmission of Plasmodium falciparum by the mosquito vector.
Khushu, M., Kissel, R. C., Kauffman, J., Taccheri, C., Singh, N., Summers, R. L., Plant, L. D., Wirth, D., Catteruccia, F., Bopp, S.
10.64898/2026.01.20.700404 — Posted: 2026-05-05
A causal link between autoantibodies and neurological symptoms in long COVID
Santos Guedes de Sa, K., Silva, J., Bayarri-Olmos, R., Baker, C., Lu, Z., Gipson, W., Na, D., Chen, B., Wenxue, L., Khosroabadi, D., Brinda, R., Alec Rath Constable, R., Omene, B., Colom Diaz, P. A., Kwon, D.-i., Rodrigues, G., Heidecke, H., Schulze-Forster, K., Gross, A., Shneer, T., Clarke, A., Linnekin, T., Brate, A., Brown, L., Buda, H., Jatiani, S., Moise, L., Greene, K., Bhagchandani, S., Bhattacharjee, B., Gehlhausen, J., Wood, J., Tabacof, L., Scheibenbogen, C., Liu, Y., Guan, L., Pane, M. S., Putrino, D., Horvath, T. L., Iwasaki, A.
10.1101/2024.06.18.24309100 — Posted: 2026-05-05
Identification and characterization of host-modulating effectors encoded by the Cluster F1 mycobacteriophage NormanBulbieJr
Wise, B. M., Edwards, K., Jirsa, C. R., Abbruzzese, S., Adebiyi, A., Bapat, S., Barnhardt, T., Bastiampillai, N., Begovic, E., Berchick, M. G., Bocco, G., Bonoris, J., Boos, E., Cassady, M., Chehab, J., Cooper, G., Coyle, H., Davis, J., De la Cruz Vargas, N., Delach, M., Dowiak, C., Ferraro, D., Fuller, M., Glasser, B., Gordon, K., Hoch, H., Holleman, S., Hood, L., Hurrell, B., Jacobs, N., Jiang, D., Kefalos, S., Maher, S., Martin, J., Mengesha, R., Merenich, D., Nayak, A., Nesterova, D., Nguyen, J., Okonkwo, C., Pompan, T., Redwood, L., Scanlon, C., Schneider, L., Shenai, A., Siatkowski, C.
10.64898/2025.12.12.693979 — Posted: 2026-05-04
Histone H3K27 methylation states are sequentially catalyzed in cycling cells
Greene, J. E., Ahmad, K., Henikoff, S.
10.64898/2026.04.30.721988 — Posted: 2026-05-04
Expression of four mitochondrial tRNAs from only two loci
Warren, J. M., Prasad, K. V. S. K., Mendez, A. M., Temnyk, S., McCutcheon, J.
10.1101/2025.11.12.688142 — Posted: 2026-05-04
Genome-wide chromatin recording resolves dynamic cell state changes
Takei, Y., Lay, J. A., Linton, J. M., Chadly, D. M., Ochiai, Y., Hadas, R., Perez, A. A., Blanco, M. R., Laurino, P., Guttman, M., Elowitz, M. B.
10.1101/2025.08.05.668773 — Posted: 2026-05-04
Changes in the Transcriptome and Synthetic Lethal Dependencies Following KRAS Mutant Expression Reveal Profound Tissue-Specificity
Martin, T. D., Choi, M. Y., McBride, J., Elledge, S. J.
10.64898/2026.04.30.721990 — Posted: 2026-05-04
Whole-body 3D kinematics of freely behaving Drosophila
Ispizua, J. I., Abe, E. T. T., Yan, J., Othayoth, R., Sawtelle, S., Atkins, F., Shiozaki, H., Meier, N. R., Wong, J., Tran, T. T., Mori, C. K., Voigts, J., Stern, D. L., Brunton, B. W., Tuthill, J. C., Johnson, R. E.
10.64898/2026.05.03.722293 — Posted: 2026-05-04

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