Channel:  The Howard Hughes Medical Institute (HHMI)

2,120 Articles

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An in planta single-cell screen to accelerate functional genetics
Lowensohn, T. N., Cody, W. B., Tsai, C., Vlahos, A. E., Call, C. C., Gao, X. J., Sattely, E. S.
10.1101/2025.08.06.668818 — Posted: 2026-02-19
Asymmetric Histone Inheritance Regulates Olfactory Stem Cell Fates During Regeneration
Ma, B., Yang, G., Yao, J., Wu, C., Vega, J. P., Manske, G., Sue, H., Sinha, S., Singh, A., Zhao, H., Chen, X.
10.1101/2025.03.02.641101 — Posted: 2026-02-19
Near real-time data on the human neutralizing antibody landscape to influenza virus as of early 2026 to inform vaccine-strain selection
Kikawa, C., Huddleston, J., Turner, S. A., Loes, A. N., Liu, J., Gang, S., Griffiths, T., Drapeau, E. M., Cowling, B. J., Ho, F., Leung, N. H., Englund, J. A., Lacombe, K., Watanabe, S., Hasegawa, H., Busch, M., Lanteri, M., Stone, M., Spencer, B., Neher, R. A., Smith, D. J., Bedford, T., Hensley, S. E., Bloom, J. D.
10.64898/2026.02.18.706711 — Posted: 2026-02-19
Phage display-mediated immuno-PCR to detect low-abundance secreted proteins in Drosophila
Han, M., Xia, B., Kim, A.-R., Filine, E., Stoneburner, E., Miao, T., Liu, Y., Zirin, J., Perrimon, N.
10.1101/2025.10.31.685841 — Posted: 2026-02-19
A conserved C. elegans zinc finger-homeodomain protein, ZFH-2, continuously required for structural integrity and function of alimentary tract and gonad
Sussfeld, A., Vidal, B., Sural, S., Merritt, D. M., Aguilar, G. R., Ramadan, Y., Hobert, O.
10.64898/2026.01.13.699069 — Posted: 2026-02-19
Deciphering epileptogenic and activity-dependent gene programs in the human brain
Lin, Q., Kang, C., Xavier, A. M., Sanchez-Martin, I., Mehta, A. D., Cheadle, L. M.
10.64898/2026.02.18.706645 — Posted: 2026-02-18
In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
Basiashvili, T., Hutchings, J., Chen, S., Karasmanis, E. P., Flaherty, W. A., Leschziner, A. E., Villa, E.
10.64898/2025.12.18.694444 — Posted: 2026-02-18
A sequence-encoded promoter proximal super pause stabilizes an offline RNA polymerase II state
Vazquez Nunez, R. J., Kesha, S., Vos, S. M.
10.64898/2026.02.18.706689 — Posted: 2026-02-18
Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans
Gao, T., Weng, C., Johnson, I., Poeschla, M., Gudera, J., King, E., Rouya, C., Donovan, A., Bourke, L., Shao, Y., Marquez, E., Tyagi, R., Zon, L. I., Weissman, J. S., Sankaran, V. G.
10.64898/2026.02.12.705660 — Posted: 2026-02-18
Nuclear tau aggregates inhibit RNA export and form by secondary seeding from cytosolic tau aggregates.
Decker, C., McCann, K., Lester, E., Pratt, J., Van Alstyne, M., Wang, Y., Parker, R.
10.64898/2026.02.17.706203 — Posted: 2026-02-18

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