Channel:  The Howard Hughes Medical Institute (HHMI)

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Polyserine-tau interactions modulate tau fibrilization
Pratt, J., McCann, K., Kuo, J., Parker, R.
10.1101/2025.06.03.657713 — Posted: 2025-06-03
Persistent dopamine-dependent remodeling of the neural transcriptome in response to pregnancy and postpartum
Chan, J. C., Di Salvo, G., Cunningham, A. M., Dutta, S., Brindley, E. A., Weekley, B. H., Wan, E., Zhang, C., Mechawar, N., Turecki, G., Maze, I.
10.1101/2025.02.20.639313 — Posted: 2025-06-02
The SHR/Akr Y chromosome reveals repeated turnover of the rat pseudoautosomal region
Bellott, D. W., Skaletsky, H., Hughes, J., Brown, L. G., Pyntikova, T., Cho, T.-J., Koutseva, N., Zaghlul, S., Kizghin, D., Mendoza, M., Raudsepp, T., Dugan, S., Khan, Z., Wang, Q., Watt, J., Worley, K. C., Scherer, S., Muzny, D. M., Gibbs, R. A., Page, D. C.
10.1101/2025.05.28.656580 — Posted: 2025-06-01
Cell-type-specific patterns and consequences of somatic mutation in development and aging brain
Kriz, A. J., Mao, S., Shao, D. D., Snellings, D. A., Andersen, R., Dong, G., Ma, C. C., Cline, H. E., Huang, A. Y., Lee, E. A., Walsh, C. A.
10.1101/2025.05.30.656844 — Posted: 2025-06-01
A primate model organism for cardiac arrhythmias identifies a magnesium transporter in pacemaker function
Chang, S., Karanewsky, C. J., Pendleton, J. L., Ren, L., Anzeraey, A., Froelicher, V., Liang, D., Razafindrakoto, A., Ravelonjanahary, H. N., Albertelli, M. A., Quertermous, T., Wright, P. C., Perret, M., Terrien, J., Aujard, F., Wu, J. C., Krasnow, M. A.
10.1101/2025.05.28.655959 — Posted: 2025-06-01
Bacterial and host enzymes modulate the inflammatory response produced by the peptidoglycan of the Lyme disease agent
McCausland, J. W., Kloos, Z. A., Irnov, I., Sonnert, N. D., Zhou, J., Putnick, R., Mueller, E. A., Steere, A. C., Palm, N. W., Grimes, C. L., Jacobs-Wagner, C.
10.1101/2025.01.08.631998 — Posted: 2025-05-31
Epigenetic and evolutionary features of ape subterminal heterochromatin
Yoo, D., Munson, K. M., Eichler, E. E.
10.1101/2025.05.29.656835 — Posted: 2025-05-30
Rapid adaptation and extinction across climates in synchronized outdoor evolution experiments of Arabidopsis thaliana
Wu, X., Bellagio, T., Peng, Y., Czech, L., Lin, M., Lang, P., Epstein, R., Abdelaziz, M., Alexander, J., Caton-Darby, M., Alonso-Blanco, C., Andersen, H. L., Berbel, M., Bergelson, J., Burghardt, L., Delker, C., Dimitrakopoulos, P. G., Donohue, K., Durka, W., Escribano-Avila, G., Franks, S. J., Fritschi, F. B., Galanidis, A., Garcia-Fernandez, A., Garcia-Munoz, A., Hamann, E., Herber, M., Hutt, A., Iriondo, J. M., Juenger, T. E., Keller, S., Koehl, K., Korte, A., Korte, P., Kuschera, A., Lara-Romero, C., Leventhal, L., Maag, D., Marcer, A., March-Salas, M., Meaux, J. d., Mendez-Vigo, B., Moren
10.1101/2025.05.28.654549 — Posted: 2025-05-28
Mechanism of age-related accumulation of mitochondrial DNA mutations in human blood
Gupta, R., Durham, T. J., Chau, G., Uddin, M. M., Lu, W., Karczewski, K. J., Howrigan, D., Natarajan, P., Zhou, W., Neale, B. M., Mootha, V. K.
10.1101/2025.05.25.655566 — Posted: 2025-05-28
Chemical capture of diazo metabolites reveals biosynthetic hydrazone oxidation
Pfeifer, K., Van Cura, D., Wu, K. J. Y., Balskus, E. P.
10.1101/2025.05.24.655970 — Posted: 2025-05-28

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