Channel:  The Howard Hughes Medical Institute (HHMI)

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Reprogramming Factors Activate a Non-Canonical Oxidative Resilience Pathway That Can Rejuvenate RPEs and Restore Vision
Lu, Y. R., Cameron, J. C., Hu, Y., Shen, H., Shirahama, S., Tyshkovskiy, A., Chen, Z., Ai, J., Zhu, D. Y., Karg, M. M., Chew, L. A., Bell, G. W., Jena, S. G., He, Y., Seifert, P., Shu, D. Y., El-Brolosy, M. A., Lou, Q., Zhang, B., Puszynska, A. M., Qiu, X., Tian, X., Gregory-Ksander, M., Gladyshev, V. N., Sinclair, D. A., Saint-Geniez, M., Buenrostro, J. D., Rickman, C. B., Ksander, B. R., Weissman, J. S.
10.1101/2025.08.30.673239 — Posted: 2025-09-01
Homology-mediated transformation of frog-killing fungus Batrachochytrium dendrobatidis illuminates chytrid development and pathogenesis
Brody, S. M., Kalinka, E., Prostak, S. M., Carvalho, T., Man, J., James, T., Fritz-Laylin, L.
10.1101/2025.08.29.673073 — Posted: 2025-08-31
Whole-transcriptome-scale and isoform-resolved spatial imaging of single cells in complex tissues
Cohen, L., Halpern, A., Blosser, T. R., Che, P., Pan, X., Zhuang, X.
10.1101/2025.08.27.672533 — Posted: 2025-08-30
Catalytic pocket of Clr4 (Suv39h) methyltransfer-ase serves as a substrate receptor for Cullin 4-dependent histone H3 ubiquitination
Psenakova, K., Parhard, S. S., Paulo, J. A., Liu, X., Patterson, E. F., Watson, R., Cheek, M. A., Keogh, M., Kalocsay, M., Gygi, S., Farnung, L., Moazed, D.
10.1101/2025.08.28.672867 — Posted: 2025-08-30
A conserved electron transport chain sensitizes Bacteroides to a pore-forming type VI secretion toxin
Ratner, H. K., Duong, B. D., Miao, P., Bertolli, S., Shen, B. A., Mitchell, U., Gallagher, L. A., Radey, M., Peterson, S. B., Mougous, J.
10.1101/2025.08.29.672963 — Posted: 2025-08-29
Endocytome profiling uncovers cell-surface protein dynamics underlying neuronal connectivity
McLaughlin, C., Ji, H., Dong, K., Xu, C., Wong, K. K. L., Li, Z., Luginbuhl, D. J., Xu, C., Lyu, C., Qin, W., Li, J., Udeshi, N., Carr, S. A., Ting, A. Y., Luo, L.
10.1101/2025.08.28.672852 — Posted: 2025-08-29
Impact of 2'-deoxyribo-purine substrates on nonenzymatic RNA template-directed primer extension
Fang, Z., Acikgoz, O., Jia, X., Essex, J., Wen, R., Szostak, J. W.
10.1101/2025.08.29.673048 — Posted: 2025-08-29
The Eukaryotic homology search complex distorts donor DNA structure to probe for homology
Woodhouse, M. V., Hu, J., Wu, M., Qian, J., Inman, J. T., Wang, M. D., Crickard, J. B.
10.1101/2025.08.28.672940 — Posted: 2025-08-28
Ten3-Lphn2-mediated target selection across the extended hippocampal network demonstrates a repeated strategy for circuit assembly
Gingrich, E. C., Pederick, D. T., Zhang, Y., Luo, L.
10.1101/2025.08.13.670207 — Posted: 2025-08-28
Inverse expression of Ten3 and Lphn2 across the developing mouse brain reveals a global strategy for circuit assembly
Chon, U., Pederick, D. T., Song, J. H., Zhang, Y., Rana, I., Luo, L.
10.1101/2025.08.13.670004 — Posted: 2025-08-28

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