Channel:  The Howard Hughes Medical Institute (HHMI)

2,006 Articles

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Pangenome discovery of missing autism variants
Sui, Y., Lin, J., Noyes, M. D., Kwon, Y., Wong, I., Koundinya, N., Harvey, W. T., Wu, M., Hoekzema, K., Munson, K. M., Garcia, G. H., Knuth, J., Wertz, J., Wang, T., Hennick, K., Karunakaran, D., Polo Prieto, R. A., Meyer-Schuman, R., Cherry, F., Pehlivan, D., Suter, B., Gustafson, J. A., Miller, D. E., Human Pangenome Reference Consortium, , Berk-Rauch, H., Nowakowski, T. J., Chakravarti, A., Zoghbi, H. Y., Eichler, E. E.
10.1101/2025.07.21.25331932 — Posted: 2025-07-22
Temperate phages enhance host fitness via RNA-guided flagellar remodeling
Walker, M. W. G., Richard, E., Wiegand, T., Wang, J., Yang, Z., Casas-Ciniglio, A. A., Hoffmann, F. T., Shahnawaz, H., Gaudet, R. G., Arpaia, N., Fernandez, I. S., Sternberg, S. H.
10.1101/2025.07.22.666180 — Posted: 2025-07-22
Mouse pups lacking a cerebral cortex develop abnormal vocal behavior
Boyd, J. L., Vargas, C., Jarvis, E. D.
10.1101/2025.07.17.665371 — Posted: 2025-07-22
Rewiring an olfactory circuit by altering the combinatorial code of cell-surface proteins
Lyu, C., Li, Z., Xu, C., Kalai, J., Luo, L.
10.1101/2025.03.01.640986 — Posted: 2025-07-19
Repulsive interactions instruct synaptic partner matching in an olfactory circuit
Li, Z., Lyu, C., Xu, C., Hu, Y., Luginbuhl, D. J., Caspi-Lebovic, A. B., Priest, J. M., Özkan, E., Luo, L.
10.1101/2025.03.01.640985 — Posted: 2025-07-19
Long-read sequencing of trios reveals increased germline and postzygotic mutation rates in repetitive DNA
Noyes, M. D., Sui, Y., Kwon, Y., Koundinya, N., Wong, I., Munson, K. M., Hoekzema, K., Kordosky, J., Garcia, G. H., Knuth, J., Lewis, A. P., Eichler, E. E.
10.1101/2025.07.18.665621 — Posted: 2025-07-19
Neuroligin-3 interaction with CSPG4 regulates normal and malignant glial precursors through PIEZO1
Gillespie, S. M., Kim, Y. S., Geraghty, A. C., Yalcin, B., Mancusi, R., Hysinger, J., Ivec, A. E., Reed, J., Drexler, R., Quezada, M., Malacon, K., Woo, P. J., Yang, A., Lam, M., Pan, Y., Zuchero, J. B., Trotter, J., Monje, M.
10.1101/2025.07.12.664340 — Posted: 2025-07-17
Programmable translational inhibition by a molecular glue-oligonucleotide conjugate
Wang, S., Kovalski, J. R., Zapatero-Belinchon, F. J., Bennett, M., Kuzuoglu-Öztürk, D., Li, Q., Stevenson, E., Liu, J., Krogan, N. J., Ott, M., Swaney, D. L., Ruggero, D., Lou, K., Shokat, K.
10.1101/2025.07.15.664547 — Posted: 2025-07-16
Complete chromosome 21 centromere sequencing of families with Down syndrome reveals centromere size asymmetry
Mastrorosa, F. K., Daponte, A., Wertz, J., Rozanski, A. N., Harvey, W. T., Porubsky, D., Knuth, J., Garcia, G., Ayllon, M., Munson, K. M., Hoekzema, K., He, W., Sherman, S. L., Allen, E. G., Rosser, T. C., Catacchio, C. R., Ventura, M., Logsdon, G. A., Eichler, E. E.
10.1101/2024.02.25.581464 — Posted: 2025-07-16
Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells
Lyu, P., Agarwal, G., Guo, C.-J., Ye, T., Weng, C., Antoszewski, M., Joubran, S., Caulier, A., Poeschla, M., Sankaran, V. G.
10.1101/2025.07.16.664824 — Posted: 2025-07-16

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