Channel:  The Howard Hughes Medical Institute (HHMI)

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L-2-hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression
Gu, W., Wang, X., Solmonson, A., Cai, L., Xiao, Y., Tasdogan, A., Franklin, J., Zhang, Y., Zhang, H., Westfall, A. K., Rowe, A., Trivedi, H., Faubert, B., Wu, Z., Sudderth, J., Zacharias, L. G., Afroze, B., Bezprozvanny, I., Sudarshan, S., Cai, F., McBrayer, S. K., Mathews, T. P., DeBerardinis, R. J.
10.1101/2025.04.16.649033 — Posted: 2025-06-24
A global map for introgressed structural variation and selection in humans
Hsieh, P., Soisangwan, N., Gordon, D., Athef Javidh, A., Harvey, W., Porubsky, D., Hoekzema, K., Baker, C., Munson, K., Kinipi, C., Leavesley, M., Brucato, N., Cox, M., RICAUT, F.-X., Gallego Romero, I., Eichler, E.
10.1101/2025.06.24.661368 — Posted: 2025-06-24
Phase separation of PGL-3 driven by structured domains that oligomerize and interact with terminal RGG motifs.
Kuroiwa, R., Sharma, P., Putnam, A., Fried, S. D., Seydoux, G.
10.1101/2025.06.23.660947 — Posted: 2025-06-24
Polo-Like Kinase 1 phosphorylation tunes the functional viscoelastic properties of the centrosome scaffold
Amato, M., Hwang, J. H., Rios, M. U., Familiari, N. E., Rosen, M. K., Woodruff, J. B.
10.1101/2024.08.29.610374 — Posted: 2025-06-24
Bacteriophages target membrane-anchored glycopolymers to promote host cell lysis and progeny release
McKitterick, A. C., Lyerly, E. W., Bernhardt, T. G.
10.1101/2025.06.24.661397 — Posted: 2025-06-24
Protein folding stress transcriptionally reprograms muscle metabolism
Paiano, J., Qadiri, M., Sharma, S., Hu, Y., Perrimon, N.
10.1101/2025.06.20.660805 — Posted: 2025-06-23
Admixture mapping reveals evidence for multiple mitonuclear incompatibilities in swordtail fish hybrids
Robles, N. V., Moran, B. M., Rodriguez Barrera, M. J., Jofre, G. I., Gunn, T., Iverson, E. N. K., Beskid, S., Baczenas, J., Sedghifar, A., Andolfatto, P., Brandvain, Y., Havird, J. C., Rosenthal, G. G., Schumer, M.
10.1101/2025.01.30.635158 — Posted: 2025-06-23
Correction: Replication of BRIT1/MCPH1 G2/M Checkpoint Function Confirms Original Conclusions
Lin, S.-Y., Dai, H., Elledge, S.
10.1101/2025.06.19.660578 — Posted: 2025-06-22
Deep Neural Networks to Register and Annotate Cells in Moving and Deforming Nervous Systems
Atanas, A. A., Lu, A. K.-Y., Goodell, B., Kim, J., Baskoylu, S., Kang, D., Kramer, T. S., Bueno, E., Wan, F. K., Cunningham, K. L., Weissbourd, B., Flavell, S. W.
10.1101/2024.07.18.601886 — Posted: 2025-06-21
A Structural Atlas of TAP Inhibition by Herpesviruses and Poxviruses
Lee, J., Manon, V., Chen, J.
10.1101/2025.06.19.660632 — Posted: 2025-06-20

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