Channel:  The Howard Hughes Medical Institute (HHMI)

2,489 Articles

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Structural mechanism of Necrocide 1 activation of human TRPM4 that triggers necrosis by sodium overload
Teixeira-Duarte, C. M., Fu, W., Zeng, W. M., Wang, J., Jiang, X., Zhao, Z., Zhong, Q., Jiang, Y.
10.64898/2026.01.28.702369 — Posted: 2026-04-08
Concordant transcriptional and morphological remodeling revealed by in vivo Perturb-CLEAR
Wu, B., Simmons, S. K., Kim, S., Li, J., Akram, M. A., Park, C. S., Zheng, X., Mendez, I., Patel, S., Chau, A., Burciu, N., Dayal, P., Nyasulu, T., Huynh, N., Clarke, G. S., Yang, X. W., Levin, J. Z., Jin, X.
10.64898/2026.04.06.716787 — Posted: 2026-04-08
Evaluating the Utility of a Nanoscale Flow Cytometer for Detection of Surface Proteins on HIV and Extracellular Vesicles
Burnie, J., Ouano, C., Costa, V., Castrosin, I., Hammond, C., Matthews, H., Tigges, J., Corbett-Helaire, K. S.
10.64898/2026.03.09.710614 — Posted: 2026-04-08
Septins regulate cytokinesis and multicellular development in the closest living relatives of animals
Carver, M., King, N.
10.64898/2026.04.05.716596 — Posted: 2026-04-07
Nascent CUT&Tag captures transcription factor binding after chromatin duplication
Wooten, M., Nguyen, K., Takushi, B. N., Ahmad, K., Henikoff, S.
10.1101/2025.10.13.682212 — Posted: 2026-04-07
A previously unappreciated class of metal-dependent bile salt hydrolases from the human gut microbiome
Cui, Z., Meng, C. J., Irwin, S. M., Augustijn, H. E., Papageorgiou, P. P., Nguyen, A. T. P., Yu, R., Aguilar Ramos, M. A., Kulik, H. J., Balskus, E. P.
10.64898/2026.04.05.716592 — Posted: 2026-04-06
Image Analysis Tools for Scanning Electron Microscopy
Shtengel, D., Shtengel, G., Xu, C. S., Hess, H. F.
10.64898/2026.03.11.711125 — Posted: 2026-04-06
A conserved in-frame stop codon acts as a multipotent defense mechanism in alphaviruses
Bhattacharya, T., Freeman, T. S., Alleman, E. M., Wang, F., Chechik, L., Emerman, M., Myles, K. M., Malik, H. S.
10.1101/2025.09.27.679005 — Posted: 2026-04-05
Sustained interferon exposure creates a hyper-metastatic subset of melanoma cells
Mannino, M., Wei, T., Moose, D. L., Knight, B., Piskounova, E., Shannon, A., Zhao, Z., Morrison, S. J.
10.64898/2026.04.01.715921 — Posted: 2026-04-05
Structure, biosynthesis, and bioactivity of nostolysamides
Weir, E., Anterola, I., van der Donk, W. A.
10.64898/2026.01.31.703028 — Posted: 2026-04-05

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