Channel:  The Howard Hughes Medical Institute (HHMI)

1,908 Articles

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Recurrent acquisition of nuclease-protease pairs in antiviral immunity
Tuck, O. T., Hu, J. J., Adler, B. A., O'Brien, C. E., Lopez, S. C., Hsieh, K., Meredith, C., Lahiri, A., Doherty, E. E., Doudna, J. A.
10.1101/2025.07.28.667249 — Posted: 2025-07-28
Cleavage of the RNA polymerase II general transcription factor TFIIB tunes transcription during stress
Gulyas, L., Lari, A., Shah, S. B., Glaunsinger, B.
10.1101/2025.07.28.667251 — Posted: 2025-07-28
Brainwide hemodynamics predict EEG neural rhythms across sleep and wakefulness in humans
Jacob, L. P. L., Bailes, S. M., Williams, S. D., Stringer, C., Lewis, L. D.
10.1101/2024.01.29.577429 — Posted: 2025-07-26
Axonal defasciculation is restricted to specific branching points during regeneration of the lateral line nerve in zebrafish
Roy, R. S., Hudspeth, A. J.
10.1101/2025.07.23.666336 — Posted: 2025-07-25
High-quality peptide evidence for annotating non-canonical open reading frames as human proteins
Deutsch, E. W., Kok, L. W., Mudge, J. M., Ruiz-Orera, J., Fierro-Monti, I., Sun, Z., Abelin, J. G., Alba, M. M., Aspden, J. L., Bazzini, A. A., Bruford, E., Brunet, M. A., Calviello, L., Carr, S. A., Carvunis, A.-R., Chothani, S., Clauwaert, J., Dean, K., Faridi, P., Frankish, A., Hubner, N., Ingolia, N., Magrane, M., Martin, M. J., Martinez, T. F., Menschaert, G., Ohler, U., Orchard, S., Rackham, O., Roucou, X., Slavoff, S. A., Valen, E., Wacholder, A. C., Weissman, J. S., Wu, W., Xie, Z., Choudhary, J., Bassani-Sternberg, M., Vizcaino, J. A., Ternette, N., Moritz, R. L., Prensner, J., van He
10.1101/2024.09.09.612016 — Posted: 2025-07-24
Synaptic sign switching mediates online dopamine updates
Li, S., Wang, W., Knipe, G., Jerng, E., Capelli, P., Zhou, C., Bilsel, E., Sabatini, B. L.
10.1101/2025.07.23.666367 — Posted: 2025-07-24
Barcoded monoclonal embryoids are a potential solution to confounding bottlenecks in mosaic organoid screens
Regalado, S. G., Qiu, C., Lalanne, J.-B., Martin, B. K., Duran, M., Trapnell, C., Keith, A., Domcke, S., Shendure, J.
10.1101/2025.05.23.655669 — Posted: 2025-07-23
Comparative Proteomic Profiling of Receptor Kinase Signaling Reveals Key Trafficking Components Enforcing Plant Stomatal Development
Bai, P., Vu, M. H., Komatsu, C., Papoulas, O., Ebine, K., Nozawa, A., Sawasaki, T., Ueda, T., Marcotte, E. M., Torii, K. U.
10.1101/2025.07.20.665823 — Posted: 2025-07-23
Lineage recording in monoclonal gastruloids reveals heritable modes of early development
Regalado, S. G., Qiu, C., Kottapalli, S., Martin, B. K., Chen, W., Liao, H., Kim, H., Li, X., Lalanne, J.-B., Hamazaki, N., Domcke, S., Choi, J., Shendure, J.
10.1101/2025.05.23.655664 — Posted: 2025-07-23
Pangenome discovery of missing autism variants
Sui, Y., Lin, J., Noyes, M. D., Kwon, Y., Wong, I., Koundinya, N., Harvey, W. T., Wu, M., Hoekzema, K., Munson, K. M., Garcia, G. H., Knuth, J., Wertz, J., Wang, T., Hennick, K., Karunakaran, D., Polo Prieto, R. A., Meyer-Schuman, R., Cherry, F., Pehlivan, D., Suter, B., Gustafson, J. A., Miller, D. E., Human Pangenome Reference Consortium, , Berk-Rauch, H., Nowakowski, T. J., Chakravarti, A., Zoghbi, H. Y., Eichler, E. E.
10.1101/2025.07.21.25331932 — Posted: 2025-07-22

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