Channel:  The Howard Hughes Medical Institute (HHMI)

2,199 Articles

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The E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation
Farnung, J., Slobodyanyuk, E., Wang, P. Y., Blodgett, L. W., Lin, D. H., von Gronau, S., Schulman, B. A., Bartel, D. P.
10.64898/2026.01.05.697729 — Posted: 2026-01-05
Integration of in situ hybridization and scRNA-seq data provides a 2D topographical map of the developing retina across species
Joisher, H. N., Lee, C., Prabhakara, C., van der Weide, I., Si, Y., Lonfat, N., Cepko, C.
10.64898/2026.01.04.697548 — Posted: 2026-01-04
mRNAbow: A versatile gene expression system for multiplexed fluorescent imaging using optimized in vitro transcribed mRNA
Choi, H., Halanych, C., Kasberg, W., Testa, M. D., Rubin-Elgressy, S., Nguyen, P., Walpita, D., Tsang, A., Cortes, D., Song, E. Y., Wu, H., Weissman, I. L., Espinosa-Medina, I., Satou, C., Song, J. L., Matus, D. Q., Lippincott-Schwartz, J.
10.64898/2026.01.02.697412 — Posted: 2026-01-02
ABCC1 protects skin dendritic cells from FITC-induced toxicity by efflux and extracellular glutathione buffering
Knopper, K., Rao, A., An, J., Cyster, J. G.
10.64898/2026.01.02.697391 — Posted: 2026-01-02
Functional and antigenic constraints on the Nipah virus fusion protein
Larsen, B. B., Harari, S., Gen, R., Stewart, C., Veesler, D., Bloom, J. D.
10.1101/2025.10.15.682664 — Posted: 2026-01-01
Memory from variability: Heritable short-term cellular memory emerges from stochastic biochemical reaction networks
Aronson, M. S., Zhou, B. Y., Fitzgerald, J. E., Sgro, A. E.
10.64898/2025.12.31.694479 — Posted: 2026-01-01
Innate immune sensing via the cGAS-STING pathway restricts extrachromosomal DNA-driven tumorigenesis
Li, T., Yang, Q.-L., Qiao, K., Zhang, A., Sun, C., Huang, H., Mischel, P. S., Wu, S., Chen, Z. J.
10.64898/2025.12.31.697191 — Posted: 2026-01-01
Mitochondrial depolarization stabilizes the vitamin B12 chaperone MMADHC in the cytosol to increase MTR activity
Rath, S. P., Li, Z., Guha, A., Dong, F., Banerjee, R., Mootha, V. K.
10.64898/2025.12.31.697091 — Posted: 2025-12-31
Extracellular matrix regulates lineage plasticity in prostate cancer through YAP/TEAD
Han, T., Sun, Z., Lange, M., Cho, Y. Z., Mcgillivray, P., Buttner, M., Kastan, N. R., Nandakumar, S., Zhao, H., Oak, S., Fong, L., Kang, W., Fan, N., Zhao, J., Salsabeel, N., Kaur, H., Mao, N., Chang, Q., Rosiek, E., Chan, E., Tipping, M., Schultz, N., Hamard, P.-J., De Stanchina, E., Pe'er, D., Koche, R. P., Chen, Z., Hudspeth, A., Sawyers, C.
10.64898/2025.12.30.697072 — Posted: 2025-12-31
A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform
Jain, S., Williamson, K. E., Ying, A. W., Turner, A. M., Jiang, R. J., Raval, S., So, K., Allison, M. P., Sankar, A., Same Guerra, D. D., Lin, Y., Jiang, Z., Mashtalir, N., Rohrs, H. W., Lichti, C. F., Muir, T. W., Papanastasiou, M., Paulo, J. A., Gygi, S. P., Gross, M. L., Kadoch, C.
10.1101/2025.08.01.667725 — Posted: 2025-12-31

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