Channel:  The Howard Hughes Medical Institute (HHMI)

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Human-specific tandem repeat in CACNA1C modulates responses to neuronal stimulation
Song, J. H., Birey, F., Hung, T.-C., Hall, N. A., Guenther, C. A., Chen, X., Alkuraya, I. F., Tunbridge, E. M., Haerty, W. `, Pasca, S. P., Kingsley, D. M.
10.1101/2025.09.15.676436 — Posted: 2025-09-16
RNA-induced PRC2 inhibition depends on the sequence of bound RNA
Song, J., Yao, L., Gooding, A. R., Thron, V., Hemphill, W. O., Goodrich, K., Kasinath, V., Cech, T. R.
10.1101/2024.08.29.610323 — Posted: 2025-09-15
Safety and immunogenicity of PanChol, a single-dose live-attenuated oral cholera vaccine: results from a phase 1a, double-blind, randomized, placebo-controlled trial
Leitner, D. R., Walsh, S. R., Suzuki, M., Desjardins, M., Hannaford, A., Sherman, A. C., Levine, H., Carr, L., Hammerness, E., Osaki, A., Sullivan, E., Wang, B., Balazs, G. I., Chang, J. B. P., Slater, D. M., Puri, N., Kuehl, C. J., Chen, W. H., Harris, J. B., Piantadosi, S., Baden, L. R., Waldor, M. K., PanChol study group
10.1101/2025.09.12.25335655 — Posted: 2025-09-14
marApp: An R package and web portal to calculate mutations- and genetic diversity-area relationship for conservation
Lin, M., Mualim, K., Selmoni, O., Exposito-Alonso, M.
10.1101/2025.09.09.675155 — Posted: 2025-09-14
Spectral envelopes of rhythmic facial movements predict intention and motor cortical representations
Hakim, R., Heo, G., Jaggi, A., Musall, S., Datta, S. R., Sabatini, B. L.
10.1101/2025.09.10.675423 — Posted: 2025-09-14
Aminoacyl-tRNA specificity of a ligase catalyzing non-ribosomal peptide extension
Nguyen, D. T., Ramos-Figueroa, J. S., Vinogradov, A. A., Goto, Y., Gadgil, M. G., Splain, R. A., Suga, H., van der Donk, W. A., Mitchell, D. A.
10.1101/2025.09.13.676032 — Posted: 2025-09-14
ACAD10 encodes two orphan enzymes in the ether lipid biosynthetic and salvage pathways
Ye, J., Purlyte, E., Lopez, V. A., Kizzar, T., Tatge, L., Mill, J., Baldwin, D., Rashan, E., Kim, J., Pagliarini, D. A., Tomchick, D. R., Pawlowski, K., Douglas, P., Simcox, J., Tagliabracci, V. S.
10.1101/2025.09.10.675409 — Posted: 2025-09-13
Atlas of innate immune responses to experimental cholera and IL22 treatment demonstrates protection by mucus-secreting cells
Suzuki, M., Hasegawa, Y., Zhang, H., Waldor, M. K.
10.1101/2025.09.12.675873 — Posted: 2025-09-12
Neutral lipid processing in glia is sexually dimorphic and promotes sleep through diacylglycerol catabolism
Pyfrom, E. S., Beveridge, C., Haynes, P. R., Kanigicherla, V. A., Randolph, C. E., Carvalho Costa, P., Negatu, S. G., Iyer, S., Killiany, S. L., Yue, Z., Astacio, E. N., Walker, K. A., Luu, K. N., Pivarshev, P. A., Jurado, K. A., Chopra, G., Sehgal, A.
10.1101/2025.09.10.674993 — Posted: 2025-09-12
HIF2-driven PTHrP Causes Cachexia and Hypercalcemia in Kidney Cancer: Treatment with HIF2 Inhibitors
Abu-Remaileh, M., Stransky, L. A., Bhalerao, N., Shirole, N. H., Jiang, Q., Saad, E., Machaalani, M., Vigeant, S. H., Woldemichael, H., Xu, C., Lu, J., Wei, H., Liu, Z., Sun, W., Enomoto, K., Choueiri, T. K., Pitarresi, J. R., Carr, S. A., Udeshi, N. D., Kaelin, W. G.
10.1101/2025.09.09.675147 — Posted: 2025-09-11

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