Channel:  The Howard Hughes Medical Institute (HHMI)

1,967 Articles

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Dual-patterned pluripotent stem cells self-organize into a human embryo model with extended anterior-posterior patterning
Liu, Z., Qiu, C., Kubo, C. A., Xu, S., Daza, R. M., Nichols, E., Yang, W., Vo, A., O'Neill, M. B., Lee, C., Shendure, J., Hamazaki, N.
10.1101/2025.09.25.678678 — Posted: 2025-09-26
Combining brainwide activity imaging and electron microscopy reveals novel nociceptive circuits
Randel, N., Wang, C., Clayton, M. S., Wang, K., Pang, S., Xu, S. C., Champion, A., Hess, H. F., Cardona, A., Keller, P. J., Zlatic, M.
10.1101/2025.09.25.678485 — Posted: 2025-09-25
Simulated climate change magnifies genetic vulnerabilities from mutation load and maladaptation
Leventhal, L., Ruffley, M. R., Carnegie Field Consortium, , Exposito-Alonso, M.
10.1101/2025.09.25.677362 — Posted: 2025-09-25
Regulation of Glypican 6-mediated Wnt activation maintains TDP-43 nuclear localization in neurons
Zhang, N., Sockanathan, S.
10.1101/2025.09.24.678385 — Posted: 2025-09-25
Observing biological spatio-angular structures and dynamics with statistical image reconstruction and polarized fluorescence microscopy
Liu, J., Chandler, T., Li, Y., Agashe, A., Wei, M., Su, Y., Wu, Y., Baskin, T. I., Jaumouille, V., Chen, J., Xu, P., Ye, H., Zhu, W., Fischer, R. S., Swaminathan, V., Nain, A. S., Mehta, S. B., La Riviere, P. J., Shroff, H., Liu, H., Guo, M.
10.1101/2025.09.23.678164 — Posted: 2025-09-25
EPOP and MTF2 Activate PRC2 Activity through DNA-sequence specificity
Granat, J., Liu, S., Popoca, L., Oksuz, O., Reinberg, D.
10.1101/2025.09.25.678634 — Posted: 2025-09-25
Dynamic changes in chromosome and nuclear architecture during maturation of normal and ALS C9orf72 motor neurons
Uyan, O., Sambare, S., Oomen, M. E., Wightman, N., Schooley, A., Klim, J. R., Belaghzal, H., Aydemir, O., Akgol-Oksuz, B., Uslu, Z. S. A., Eggan, K., Brown, R. H., Dekker, J.
10.1101/2025.09.22.677835 — Posted: 2025-09-23
CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via histone H1
Wang, S., Li, T., Naish, M., Chuang, R., Lin, E. K., Fonkalsrud, C., Yan, H., Feng, S., Henderson, I. R., Jacobsen, S. E.
10.1101/2025.09.22.677529 — Posted: 2025-09-22
Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits
Ruetten, V. M., Zheng, W., Siwanowicz, I. R., Mensh, B. D., Eddison, M., Hu, A., Chi, Y., Lemire, A. L., Guo, C., Kadobianskyi, M., Renz, M., Lelek-Greskovic, S., He, Y., Close, K., Ihrke, G., Dev, A., Petruncio, A., Wan, Y., Engert, F., Fishman, M. C., Judkewitz, B., Rubinov, M., Keller, P. J., Satou, C., Yu, G., Tillberg, P. W., Sahani, M., Ahrens, M. B.
10.1101/2025.08.20.670374 — Posted: 2025-09-20
Spatial predictive coding in visual cortical neurons
Zhang, Q., Grodem, S., Gracias, A., Lensjo, K. K., Fyhn, M., Stringer, C., Pachitariu, M.
10.1101/2025.09.17.676794 — Posted: 2025-09-19

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