Channel: The Howard Hughes Medical Institute (HHMI)

2,489 Articles

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GLP-1 analogs restore inflammatory, mitochondrial and intercellular signaling networks in the SncaG51D/G51D knock-in mouse model of Parkinson's disease

Vaidya, B., Li, Y., Kim, Y., Osterman, C., Revelli, J.-P., Zoghbi, H. Y.

10.64898/2026.05.18.726024 — Posted: 2026-05-19

Vision shapes neural maps of space through an ancient midbrain pathway

Brenner, J. M., Ruediger, S., Wilhite, C., Regalado, J. M., Senzai, Y., Voskobiynyk, Y., Paz, J. T., Scanziani, M., Beltramo, R.

10.64898/2026.05.16.725555 — Posted: 2026-05-19

Bumble bee workers adopt novel behavioral roles and reshape their social networks in the absence of a queen

Ruttenberg, D. M., Wolf, S. W., Webb, A. E., Wyman, E. S., White, M., Melo, D., Traniello, I. M., Kocher, S. D.

10.1101/2025.01.07.630106 — Posted: 2026-05-19

Genomic epidemiology as a tool for understanding drivers of hepatitis A community outbreaks in Massachusetts and New Hampshire

Krasilnikova, L. A., Bouton, L., Brock-Fisher, T. M., Decker, E., Godec, M., Thompson, Z., Dart, E., Gao, F., Gladden-Young, A., Messer, K. S., Norville, J., Specht, I., Osinski, A., Li, J., Lones, C., DeRuff, K. C., Siddle, K. J., Church, D., Benton, C., Hansen, K., Bowen, H., Bhattacharyya, S., Epie, N., Brown, C. M., Madoff, L. C., MacInnis, B. L., Gallagher, G. R., Smole, S., Bean, C., Talbot, E. A., Burns, M., Doucette, M., Fortes, E., Park, D. J., Sabeti, P. C., Wohl, S.

10.64898/2026.05.14.26352933 — Posted: 2026-05-19

Rapid centromere turnover and the adaptive radiation of lemurs

Trivedi, M., Gianfrate, F., de Gennaro, L., Ayllon, M., Munson, K. M., Hoekzema, K., Yoo, D., Ehmke, E., Yoder, A. D., Chang, S., Lalgudi, C., Krasnow, M. A., Ventura, M., Eichler, E. E.

10.64898/2026.05.16.725662 — Posted: 2026-05-19

KAS-CUT&Tag for direct mapping of transcription bubbles

Wu, W., Greene, J. E., Ahmad, K., Henikoff, S.

10.64898/2026.05.15.725569 — Posted: 2026-05-19

Sex-specific plasticity mechanisms mediating fear extinction

Graham, K., Tuck, J., O'Brien, G. K., Webber, L. K., Drillen, A. L., Coddington, L. T., Zhao, X., Bloss, E. B.

10.64898/2026.04.10.717763 — Posted: 2026-05-19

Sequence alignment of the primate lineage reveals evolutionary divergence and conserved secondary structural motifs in noncoding RNAs

Beeram, A., Perry, Z. R., Pyle, A. M.

10.64898/2026.05.18.725462 — Posted: 2026-05-19

Global cell-state and gene-program representations reveal conserved and context-specific perturbation responses of cells

Pan, X., Saunders, R., Replogle, J. M., Weissman, J. S., Zhuang, X.