Channel:  The Howard Hughes Medical Institute (HHMI)

2,566 Articles

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Mechanism of tandem-repeat DNA synthesis by an antiviral reverse transcriptase
Ramirez, J. L., He, Q., Wiegand, T., Lampe, G., Wang, J., Tang, S., Fernandez, I. S., Sternberg, S. H.
10.64898/2026.06.29.735271 — Posted: 2026-06-29
Maternal experience alters brain-wide representation of infant cries
McRae, B. R., Ferguson, D.-L. K. D., Swanier, K., Allen, G. I., Marlin, B. J.
10.64898/2026.06.26.734581 — Posted: 2026-06-28
The genomic origins and evolutionary path to a key innovation in the world's most venomous snakes
van Thiel, J., Dowell, N., Smith, C. F., Sanchez, E. E., Carroll, S.
10.64898/2026.06.23.733212 — Posted: 2026-06-28
Peri-Locus Coeruleus Controls Endothelial Cell Heterogeneity in Enriched Environments via Region-Specific Norepinephrine Signaling
Zhao, Y., Li, B., Ju, F., Feng, J., Wei, J.-a., Shao, J., Sun, W., Chen, S., Qiu, Y., Gao, D., Zhang, L., Chen, Y., Li, Y., Wang, L., Tu, J., Yang, F.
10.64898/2026.06.23.733358 — Posted: 2026-06-28
The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome
Shen, B. A., Asfahl, K. L., Lim, B., Bertolli, S. K., Minot, S. S., Radey, M. C., Penewit, K., Ngo, B., Salipante, S. J., Johnston, C. D., Peterson, S. B., Goodman, A. L., Mougous, J. D.
10.1101/2025.11.29.690828 — Posted: 2026-06-26
A Noncontiguous Code for RNA-Guided DNA Recognition Preceded CRISPR
Yoon, P. H., Loi, K., Zhang, Z., Docter, T. A., Lopez, S. C., Langeberg, C. J., ur-Rehman, M. M., Vohra, K., Zhou, Z., Shi, H., Boger, R., Wang, P. Y., Adler, B. A., Brohawn, S. G., Doudna, J. A.
10.64898/2026.04.26.720920 — Posted: 2026-06-25
PARP1 Exhibits an Enzymatically Inactive Chromatin Binding Mode
Fiorenza, A., Anand, M., Luger, K.
10.64898/2026.06.24.734344 — Posted: 2026-06-25
Structural Basis of Human Kinetochore-Microtubule Coupling by the Ndc80 and Ska Complexes
Zhou, J., Saha, I., Siahaan, V., Zhao, Y., Janke, C., Yildiz, A., Nogales, E.
10.64898/2025.12.06.692780 — Posted: 2026-06-25
Development of GS-441524 Derivatives as Potent SARS-CoV-2 Mac1 Inhibitors via a Direct-to-Biology Approach
Peng, K., Chakraborty, S., Wallace, S. D., Noll, J. C. G., Shang, J., Lu, X., Choi, A., Whittaker, G., Fromme, J. C., Lin, H.
10.64898/2026.06.24.734322 — Posted: 2026-06-25
A genetic toolkit to reduce wheat immunogenicity and incidence of celiac disease
Rottersman, M. G., Laudencia-Chingcuanco, D., Zhang, W., Guzman-Lopez, M. H., Lin, J. W., Zhang, J., Caseys, C., Burguener, G., Kim, S., Zhang, X., Yunusbaev, U., Akhunov, E., Lee, J.-Y., Dubcovsky, J.
10.64898/2026.06.23.734071 — Posted: 2026-06-25

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