Channel:  The Howard Hughes Medical Institute (HHMI)

1,912 Articles

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Whole-transcriptome-scale and isoform-resolved spatial imaging of single cells in complex tissues
Cohen, L., Halpern, A., Blosser, T. R., Che, P., Pan, X., Zhuang, X.
10.1101/2025.08.27.672533 — Posted: 2025-08-30
Impact of 2'-deoxyribo-purine substrates on nonenzymatic RNA template-directed primer extension
Fang, Z., Acikgoz, O., Jia, X., Essex, J., Wen, R., Szostak, J. W.
10.1101/2025.08.29.673048 — Posted: 2025-08-29
A conserved electron transport chain sensitizes Bacteroides to a pore-forming type VI secretion toxin
Ratner, H. K., Duong, B. D., Miao, P., Bertolli, S., Shen, B. A., Mitchell, U., Gallagher, L. A., Radey, M., Peterson, S. B., Mougous, J.
10.1101/2025.08.29.672963 — Posted: 2025-08-29
Discovery of homoharringtonine pathway enzymes reveals a whole plant model for coordinated biosynthesis
Dho, Y., Smith, K., Sattely, E. S.
10.1101/2025.08.26.672243 — Posted: 2025-08-29
Endocytome profiling uncovers cell-surface protein dynamics underlying neuronal connectivity
McLaughlin, C., Ji, H., Dong, K., Xu, C., Wong, K. K. L., Li, Z., Luginbuhl, D. J., Xu, C., Lyu, C., Qin, W., Li, J., Udeshi, N., Carr, S. A., Ting, A. Y., Luo, L.
10.1101/2025.08.28.672852 — Posted: 2025-08-29
Ten3-Lphn2-mediated target selection across the extended hippocampal network demonstrates a repeated strategy for circuit assembly
Gingrich, E. C., Pederick, D. T., Zhang, Y., Luo, L.
10.1101/2025.08.13.670207 — Posted: 2025-08-28
Inverse expression of Ten3 and Lphn2 across the developing mouse brain reveals a global strategy for circuit assembly
Chon, U., Pederick, D. T., Song, J. H., Zhang, Y., Rana, I., Luo, L.
10.1101/2025.08.13.670004 — Posted: 2025-08-28
Tissue-specific clonal selection and differentiation of CD4+ T cells during infection
Parsa, R., Carvalho de Assis, H., B.R. de Castro, T., Lima dos Reis, G., Hartweger, H., Bilate, A., Mucida, D.
10.1101/2025.08.25.672130 — Posted: 2025-08-28
The Eukaryotic homology search complex distorts donor DNA structure to probe for homology
Woodhouse, M. V., Hu, J., Wu, M., Qian, J., Inman, J. T., Wang, M. D., Crickard, J. B.
10.1101/2025.08.28.672940 — Posted: 2025-08-28
Positive Selection Screen for Natural Product β-Catenin Inactivators
Boudreau, M. W., Freire, V. F., Corbett, S. C., Martinez-Fructuoso, L., Kumar, R., Thornburg, C. C., Akee, R. K., Peyser, B. D., Jiang, Q., Splaine, J., Pfaff, J. L., Chandler, B. C., Abeja, D. M., Donovan, K. A., Che, J., Lampson, B. L., Szajner, P., Smith, J. A., Koduri, V., Grkovic, T., OKeefe, B. R., Kaelin, W. G.
10.1101/2025.08.27.671140 — Posted: 2025-08-27

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