Channel:  The Howard Hughes Medical Institute (HHMI)

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Nonenzymatic RNA copying with a potentially primordial genetic alphabet
Fang, Z., Jia, X., Xing, Y., Szostak, J. W.
10.1101/2025.03.19.644114 — Posted: 2025-03-19
Discovery of neuronal cell types by pairing whole cell reconstructions with RNA expression profiles
Ferreira, T. A., Eddison, M., Copeland, M., Lay, M., Tenshaw, E., Weldon, M., Schauder, D., Olbris, D. J., Rokicki, K., Spruston, N., Tillberg, P. W., Chandrashekar, J., Korff, W., Dudman, J. T., The MouseLight Project Team
10.1101/2024.12.30.630829 — Posted: 2025-03-18
RCVT: a diagnostic to quantify compositional biases among taxa for large phylogenomic studies
Steenwyk, J. L., Buida, T. J.
10.1101/2024.11.28.625917 — Posted: 2025-03-18
Type IV pili-associated secretion of a biofilm matrix protein from Clostridium perfringens that forms intermolecular isopeptide bonds
Kivimaki, S. E., Dempsey, S., Tani, J. M., Camper, C., Hicklin, I. K., Blaby-Haas, C. E., Brown, A. M., Melville, S.
10.1101/2024.11.04.621531 — Posted: 2025-03-17
A genome-scale drug discovery pipeline uncovers new therapeutic targets and a unique p97 allosteric binding site in Schistosoma mansoni
Stephens, D. R., Fung, H. Y. J., Han, Y., Liang, J., Chen, Z., Ready, J., Collins, J.
10.1101/2025.03.14.643303 — Posted: 2025-03-15
Nonequilibrium polysome dynamics promote chromosome segregation and its coupling to cell growth in Escherichia coli
Papagiannakis, A., Yu, Q., Govers, S. K., Lin, W.-H., Wingreen, N. S., Jacobs-Wagner, C.
10.1101/2024.10.08.617237 — Posted: 2025-03-15
HortaCloud: An Open and Collaborative Platform for Whole Brain Neuronal Reconstructions
Rokicki, K., Schauder, D., Olbris, D. J., Goina, C., Clements, J., Edson, P., Kawase, T., Svirskas, R., Arshadi, C., Feng, D., Chandrashekar, J., Ferreira, T. A., MouseLight Project Team
10.1101/2025.03.13.642887 — Posted: 2025-03-14
Design of solubly expressed miniaturized SMART MHCs
White, W. L., Bai, H., Kim, C. J., Jude, K. M., Sun, R., Guerrero, L., Han, X., Chen, X. T., Chaudhuri, A., Bonzanini, J. E., Sun, Y., Onwuka, A. E., Wang, N., Wang, C., Li, X., Goreshnik, I., Allen, A., Levine, P. M., Kueh, H. Y., Jewett, M. C., Sgourakis, N., Achour, A., Garcia, K. C., Baker, D.
10.1101/2025.03.14.643101 — Posted: 2025-03-14
Canonical Wnt Signaling Suppresses Brain Endothelial Cell Transcytosis to Maintain Blood-Brain Barrier Integrity
du Maine, X., Gu, C.
10.1101/2025.03.10.642437 — Posted: 2025-03-13
Engineering Multiplexed Synthetic Breath Biomarkers as Diagnostic Probes
Wang, S.-T., Anahtar, M., Kim, D. M., Samad, T. S., Zhang, C. M., Patel, S., Ko, H., Ngambenjawong, C., Wang, C. S., Kirkpatrick, J. D., Kumar, V., Fleming, H. E., Bhatia, S. N.
10.1101/2024.12.30.630769 — Posted: 2025-03-13

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