Channel:  The Howard Hughes Medical Institute (HHMI)

2,492 Articles

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Discovery of a Human Metabolite that Mimics the Bacterial Quorum-Sensing Autoinducer AI-2
Shine, E., Valastyan, J. S., Ying, V. Y., Huang, J. Z., Seyedsayamdost, M. R., Bassler, B. L.
10.64898/2026.01.16.699917 — Posted: 2026-01-17
Tumor-induced orexigenic imbalance lowers protein appetite and drives early organ wasting symptoms
Petsakou, A., Filine, E., Li, M., Chen, Y., Zheng, A., Perrimon, N.
10.1101/2025.01.02.631110 — Posted: 2026-01-16
Monitoring of plasma and urine tumor-derived DNA to inform bladder-sparing approaches for patients with muscle-invasive bladder cancer
Galsky, M. D., Izadmehr, S., Yu, M., Curtis, S. D., Douville, C., Popoli, M., Ptak, J., Dobbyn, L., Silliman, N., Chan, K. G., Dorff, T. B., Cetnar, J. P., O'Neil, B., D'Souza, A., Mamtani, R., Kyriakopoulos, C. E., Brody, R., Sadimin, E., Mehrazin, R., Chowell, D., Sfakianos, J., Daneshmand, S., Pal, S. K., Bettegowda, C., Kinzler, K. W., Papadopoulos, N., Vogelstein, B., Wang, Y.
10.64898/2026.01.14.26344033 — Posted: 2026-01-16
Hypomethylation on cfDNA within transposable elements can predict ovarian malignancy in women with adnexal masses
Weigert, M., Cui, X., Zhang, P., Kowitwanich, K., West-Szymanski, D., Rauch, S., Zhang, W., He, C., Lengyel, E.
10.64898/2026.01.14.26344128 — Posted: 2026-01-16
NPEPPS segmental duplication drives position effect expression of TBC1D3 in the human brain
Guitart, X., Brunner, J. W., Ren, L., Jeong, H., Yoo, D., Porubsky, D., Vollger, M. R., Hoekzema, K., Munson, K. M., Sun, K., Ayllon, M., Hoglin, K., McMullen, R., Pavlovic, B., Pollen, A. A., Eichler, E. E.
10.64898/2026.01.14.699559 — Posted: 2026-01-15
Modular gene tagging in C. elegans
Hefel, A., Kruse, K., Wall, K., Jorgensen, S. B., Ng, K. H., Stolley, R., Rich, M. S., Jorgensen, E. M.
10.64898/2026.01.15.699741 — Posted: 2026-01-15
The Drosophila proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth
Ewen-Campen, B., Chen, W., Gopal Tattikota, S., Liu, Y., Hu, Y., Perrimon, N.
10.1101/2025.06.27.662004 — Posted: 2026-01-14
A single cluster of RNA Polymerase II molecules is stably associated with active genes
Mukherjee, A., Kapoor, M., Shankta, K., Fallacaro, S., Carter, R. D., Hayward-Lara, G., Ratchasanmuang, P., Haloush, Y. I., Mir, M.
10.1101/2025.02.10.637507 — Posted: 2026-01-14
BMP-dependent oligoclonal cancer attractor state precedes neural crest fate in melanoma initiation
McConnell, A. M., Chasse, M. H., Noonan, H. R., Mito, J. K., Barbano, J., Weiskopf, E., Gosselink, I. F., Yang, S., Drake, K. D., Baron, C. S., Layne, E., Prasad, M., Abarzua, P., Grimont, M., Kao, Y.-C., Lian, C. G., Eberhardt, A., Donzel, M., Lee, K. J., Yeh, I., Murphy, G. F., Stark, M. S., Dalle, S., Caramel, J., Trapnell, C., Zon, L. I.
10.1101/2024.10.22.618007 — Posted: 2026-01-13
Sibling chimerism among microglia in marmosets
del Rosario, R. C. H., Krienen, F. M., Zhang, Q., Goldman, M., Mello, C., Lutservitz, A., Ichihara, K., Wysoker, A., Nemesh, J., Feng, G., McCarroll, S. A.
10.1101/2023.10.16.562516 — Posted: 2026-01-13

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