Channel:  The Howard Hughes Medical Institute (HHMI)

2,006 Articles

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Superinfection with intact HIV-1 results in conditional replication of defective proviruses and nonsuppressible viremia in people living with HIV-1
Hariharan, V., White, J. A., Dragoni, F., Fray, E. J., Pathoulas, N., Moskovljevic, M., Zhang, H., Singhal, A., Lai, J., Beg, S. A., Scully, E. P., Gilliams, E. A., Block, D. S., Keruly, J., Moore, R. D., Siliciano, J. D., Simonetti, F. R., Siliciano, R. F.
10.1101/2025.04.04.647291 — Posted: 2025-04-04
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM
Hanna, M. G., Rodriguez Cruz, H. O., Fujise, K., Wu, Y., Xu, C. S., Pang, S., Zhuoning, L., Monetti, M., De Camilli, P.
10.1101/2024.09.28.615015 — Posted: 2025-04-03
Perinatal Elimination of Genetically Aberrant Neurons from Human Cerebral Cortex
Shao, D. D., Zhao, Y., Brew, J., Ghosh, U., Luquette, L. J., Zhao, S., Kriz, A. J., Qian, X., Viswanadham, V. V., Taketomi, T., Tsuruta, F., Park, P. J., Walsh, C. A.
10.1101/2024.10.08.617159 — Posted: 2025-04-03
The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture
Navarro, P. P., Vettiger, A., Hajdu, R., Ananda, V. Y., Lopez-Tavares, A., Schmid, E., Walter, J., Loose, M., Chao, L. H., Bernhardt, T. G.
10.1101/2025.04.02.646830 — Posted: 2025-04-02
Striatal neural ensemble codes for voluntary locomotor and involuntary dyskinetic movements
Chattree, G., Chrapkiewicz, R., Zhang, Y., Li, J., Schnitzer, M. J.
10.1101/2025.04.01.646527 — Posted: 2025-04-02
A miniature CRISPR-Cas10 enzyme confers immunity by an inverse signaling pathway
Doherty, E. E., Adler, B. A., Yoon, P. H., Hsieh, K., Loi, K., Armbruster, E. G., Lahiri, A., Bolling, C. S., Wilcox, X. E., Akkati, A., Iavarone, A. T., Pogliano, J., Doudna, J. A.
10.1101/2025.03.28.646030 — Posted: 2025-04-01
NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT
Wu, Z., Nguyen, P. T., Sondhi, V., Yao, R.-W., Dai, T., Chiang, J.-C., Shang, Z., Cai, F., Zhang, J., Moore, M. D., Alshamleh, I., Li, X., Ogu, T., Zacharias, L. G., Winston, R., Patricio, J. S., Johnson, X., Chen, W.-M., Cong, Q., Mathews, T. P., Zhang, Y., DeBerardinis, R. J.
10.1101/2025.03.29.646096 — Posted: 2025-04-01
Mechanistic insights into direct DNA and RNA strand transfer and dynamic protein exchange of SSB and RPA
Paul, T., Lee, I.-R., Pangeni, S., Rashid, F., Yang, O., Antony, E., Berger, J. M., Myong, S., Ha, T.
10.1101/2025.04.01.643995 — Posted: 2025-04-01
SIRT2 Mediates Integrated Stress Response by Deacetylating and Stabilizing 4EBP1 to Suppress Translation
Zi, Y., Wang, M., Hou, D., Cerione, R. A., Lin, H.
10.1101/2025.03.31.646365 — Posted: 2025-04-01
Human-chimpanzee tetraploid system defines mechanisms of species-specific neural gene regulation
Song, J. H., Carter, A. C., Bushinsky, E. M., Beck, S. G., Petrocelli, J. E., Koreman, G. T., Babu, J., Kingsley, D. M., Greenberg, M. E., Walsh, C. A.
10.1101/2025.03.31.646367 — Posted: 2025-03-31

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