Channel:  The Howard Hughes Medical Institute (HHMI)

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Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer
Koochaki, P., Qiu, B., Coker, J. A., Earsley, A., Wang, N. S., Romigh, T., Goins, C. M., Stauffer, S. R., Boudker, O., Chakraborty, A. A.
10.1101/2025.07.03.663021 — Posted: 2025-07-07
Ultrasound imaging of in situ transcriptional activity in opaque tissue
Shivaei, S., Cheung, K. Y. M., Yadav, A., Hurvitz, I. U., Lee, S., Revilla, J., Rabut, C., Criado-Hidalgo, E., Zhang, R. J., Shapiro, M. G.
10.1101/2025.07.06.663365 — Posted: 2025-07-07
Evidence for non-optimal codon choice in highly transcribed sex-biased genes of Drosophila melanogaster
Whittle, C. A., Extavour, C. G.
10.1101/2024.11.24.625100 — Posted: 2025-07-07
Discovery of oxyacanthine dihydrochloride monohydrate polymorphs from obfuscated samples by MicroED
Lin, J., Paz, O., Unge, J., Gonen, T.
10.1101/2025.07.03.663078 — Posted: 2025-07-05
Cholinergic Signaling Modulates Intestinal Pathophysiology in a Drosophila Model of Cystic Fibrosis
Lane, E., Petsakou, A., Liu, Y., Chen, W., Qadiri, M., Hu, Y., Perrimon, N.
10.1101/2025.07.02.662792 — Posted: 2025-07-05
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex
Salazar, M. P. R., Kolanukuduru, S., Ramirez, V., Lyu, B., Manigault, G., Sejourne, G., Sesaki, H., Yu, G., Eroglu, C.
10.1101/2024.10.22.619706 — Posted: 2025-07-03
Multimodal profiling of proinflammatory protease activity identifies caspase-1 as a target for lung cancer interception
Wang, C. S., Zhong, Q., Wang, S.-T., Alonso, M. C. M., Neaher, S., Patel, S., Parisi, T., Kirkpatrick, J. D., Sequist, L. V., Jacks, T. E., Bhatia, S.
10.1101/2025.07.01.662195 — Posted: 2025-07-02
DNA polymerase α-primase can function as a translesion DNA polymerase
Mayle, R., Georgescu, R., O'Donnell, M. E.
10.1101/2025.07.02.662785 — Posted: 2025-07-02
Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503
LaVigne, C. A., Han, J., Zhang, H., Cho, S., Kim, M., Sethia, K., Evers, B. M., Acharya, A., Chang, T.-C., Mendell, J. T.
10.1101/2025.06.30.662380 — Posted: 2025-07-01
Ligand-induced ubiquitination regulates endocytosis and homeostasis of the ERECTA receptor kinase for stomatal development
Chen, L., Vu, M. H., Cochran, A. M., Ying, C. F., Torii, K. U.
10.1101/2025.06.29.662054 — Posted: 2025-07-01

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