Channel:  The Howard Hughes Medical Institute (HHMI)

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Monitoring of plasma and urine tumor-derived DNA to inform bladder-sparing approaches for patients with muscle-invasive bladder cancer
Galsky, M. D., Izadmehr, S., Yu, M., Curtis, S. D., Douville, C., Popoli, M., Ptak, J., Dobbyn, L., Silliman, N., Chan, K. G., Dorff, T. B., Cetnar, J. P., O'Neil, B., D'Souza, A., Mamtani, R., Kyriakopoulos, C. E., Brody, R., Sadimin, E., Mehrazin, R., Chowell, D., Sfakianos, J., Daneshmand, S., Pal, S. K., Bettegowda, C., Kinzler, K. W., Papadopoulos, N., Vogelstein, B., Wang, Y.
10.64898/2026.01.14.26344033 — Posted: 2026-01-16
Hypomethylation on cfDNA within transposable elements can predict ovarian malignancy in women with adnexal masses
Weigert, M., Cui, X., Zhang, P., Kowitwanich, K., West-Szymanski, D., Rauch, S., Zhang, W., He, C., Lengyel, E.
10.64898/2026.01.14.26344128 — Posted: 2026-01-16
Modular gene tagging in C. elegans
Hefel, A., Kruse, K., Wall, K., Jorgensen, S. B., Ng, K. H., Stolley, R., Rich, M. S., Jorgensen, E. M.
10.64898/2026.01.15.699741 — Posted: 2026-01-15
NPEPPS segmental duplication drives position effect expression of TBC1D3 in the human brain
Guitart, X., Brunner, J. W., Ren, L., Jeong, H., Yoo, D., Porubsky, D., Vollger, M. R., Hoekzema, K., Munson, K. M., Sun, K., Ayllon, M., Hoglin, K., McMullen, R., Pavlovic, B., Pollen, A. A., Eichler, E. E.
10.64898/2026.01.14.699559 — Posted: 2026-01-15
A single cluster of RNA Polymerase II molecules is stably associated with active genes
Mukherjee, A., Kapoor, M., Shankta, K., Fallacaro, S., Carter, R. D., Hayward-Lara, G., Ratchasanmuang, P., Haloush, Y. I., Mir, M.
10.1101/2025.02.10.637507 — Posted: 2026-01-14
Unifying phylogenetic traversal and deep learning to guide tree exploration
Collienne, L., Richman, H., Rich, D. H., Barker, M., Jennings-Shaffer, C., Matsen, F. A.
10.64898/2026.01.14.699358 — Posted: 2026-01-14
The Drosophila proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth
Ewen-Campen, B., Chen, W., Gopal Tattikota, S., Liu, Y., Hu, Y., Perrimon, N.
10.1101/2025.06.27.662004 — Posted: 2026-01-14
Geometry of Braided DNA Dictates Supercoiling Partitioning
Hong, Y., Singh, G., Wang, H., Park, S. h., Wang, M. D.
10.1101/2024.10.08.617221 — Posted: 2026-01-13
Ultra-deep duplex sequencing reveals unique features of somatic evolution in the normal tissues of a family with Li-Fraumeni syndrome
Colegrove, H. L., Dubard-Gault, M. E., Marshall, H., Kohrn, B. F., Smith, T. H., Norgaard, Z. K., Lo, F. Y., Schmidt, E. K., Higgins, J. E., Valentine, C. C., Marshall, D. A., Clark, J. I., Konnick, E. Q., Salk, J. J., Horwitz, M. S., Rahbari, R., Feder, A. F., Risques, R. A.
10.64898/2026.01.12.699071 — Posted: 2026-01-13
BMP-dependent oligoclonal cancer attractor state precedes neural crest fate in melanoma initiation
McConnell, A. M., Chasse, M. H., Noonan, H. R., Mito, J. K., Barbano, J., Weiskopf, E., Gosselink, I. F., Yang, S., Drake, K. D., Baron, C. S., Layne, E., Prasad, M., Abarzua, P., Grimont, M., Kao, Y.-C., Lian, C. G., Eberhardt, A., Donzel, M., Lee, K. J., Yeh, I., Murphy, G. F., Stark, M. S., Dalle, S., Caramel, J., Trapnell, C., Zon, L. I.
10.1101/2024.10.22.618007 — Posted: 2026-01-13

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