Channel: The Howard Hughes Medical Institute (HHMI)

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Humanized Extracellular Vesicles for Efficient RNA Delivery

Ma, X., Zhao, S. R., Cepko, C. L.

10.64898/2025.12.15.694436 — Posted: 2025-12-17

Mitochondria-derived PEP licenses glycerolipid synthesis via SLC25A35

Yamamuro, T., Katoh, D., Silva, G. M., Nishida, H., Oikawa, S., Higuchi, Y., Wang, D., Fujimoto, M., Yoshida, N., Li, M., Shin, J., Zhao, Z., Yook, J.-S., Sun, L., Kajimura, S.

10.64898/2025.12.12.693842 — Posted: 2025-12-16

The Drosophila maternal-effect gene abnormal oocyte (ao) does not repress histone gene expression

Takenaka, R., Albanese, E. H., Simmerman, S. M., Verghese, S., Maddox, M. A. E., de la Cruz, A., Young, J. M., Schmidt, C. A., Rieder, L. E., Malik, H. S.

10.1101/2024.09.17.613536 — Posted: 2025-12-16

A signature-agnostic test for differences between tumor mutation spectra reveals carcinogen and ancestry effects

Hart, S. F. M., Alcala, N., Feder, A. F., Harris, K.

10.1101/2025.05.15.654154 — Posted: 2025-12-16

Neuroligin-2 is ubiquitinated by Nedd4l to control developmental astrocyte morphogenesis.

Sakers, K., Ramirez, J. J., Elazar, N., Nagendren, L., Soderblom, E. J., Eroglu, C.

10.64898/2025.12.15.694023 — Posted: 2025-12-16

Conserved phenotype and function of human brain border-associated macrophages in iPSC-derived models

Barr, H. J., Depp, C., Hingerl, M., Nguyen, T., Reimertz, J. M., Connolly, E., Patel, J., Doman, J. L., Marsh, S. E., Stevens, B.

10.64898/2025.12.11.693582 — Posted: 2025-12-14

Phosphatase SHP2 pathogenic mutations enhance activity by altering conformational sampling

Glaser, A., Padua, R., Ojoawo, A., Sullivan, C., Kern, D.