Channel:  The Howard Hughes Medical Institute (HHMI)

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The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity
Lai, S.-L., Doe, C. Q.
10.1101/2025.09.26.678798 — Posted: 2025-12-03
Elucidating an anterior cingulate circuit for self-initiated actions and rescue of Parkinsonian akinesia
Ulloa Severino, F., Lu, B., Kim, J., Friedman, A., Roshchina, M., Johnson, S., Bakhurin, K., Eroglu, C., Yin, H.
10.64898/2025.12.01.691607 — Posted: 2025-12-03
Ultrasonic Reporter of Kinase Activity
Yang, J. W., Jin, Z., Wang, T. Y., Shapiro, M. G.
10.64898/2025.11.30.691048 — Posted: 2025-12-02
miRNA modules for precise, tunable control of gene expression
Du, R., Flynn, M. J., Mahe, K., Honsa, M., Gu, B., Li, D., McGeary, S. E., Gradinaru, V., Jungmann, R., Elowitz, M. B.
10.1101/2024.03.12.583048 — Posted: 2025-12-02
Need-selective gating of dopamine neuron cue responses by real and virtual hunger
Mamaligas, A. A., Berke, J., Kreitzer, A. C., Knight, Z. A.
10.64898/2025.11.29.691326 — Posted: 2025-12-02
High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains
Kikawa, C., Loes, A. N., Huddleston, J., Figgins, M. D., Steinberg, P., Griffiths, T., Drapeau, E. M., Peck, H., Barr, I. G., Englund, J. A., Hensley, S. E., Bedford, T., Bloom, J. D.
10.1101/2025.03.04.641544 — Posted: 2025-12-02
Sleep controls peroxisomal abundance to reduce wake-induced brain oxidation
Guevara, C., Li, Y., Pyfrom, E. S., Killiany, S., Yue, Z., Sehgal, A.
10.1101/2025.11.28.691144 — Posted: 2025-12-01
Naegleria amoebae seek confinement and crawl persistently through narrow spaces
Velle, K., Ramaswamy, M., Hokmabad, B. V., Martin-Perez, T., Carrasco, T. T., Callahan, W. S., Kim, H. S., Datta, S. S., Edwards, M., Fritz-Laylin, L.
10.1101/2025.11.30.691445 — Posted: 2025-12-01
Molecular interplay between the DNA damage checkpoint kinase Mec1-Ddc2 and its activator Dpb11 on gapped DNA
Beckwitt, E. C., Chua, G. N. L., Liu, S., O'Donnell, M. E.
10.1101/2025.11.28.691181 — Posted: 2025-11-30
Orthosteric Molecular Glue Inhibits COP9 Signalosome with Substrate-Dependent Potency
Shi, H., Wang, X., Yu, C., Mao, H., Jiao, F., Braitbard, M., Shor, B., Zhang, Z., Hinds, T. R., Cao, S., Fan, E., Schneidman-Duhovny, D., Huang, L., Zheng, N.
10.1101/2025.11.26.690573 — Posted: 2025-11-30

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