Channel:  The Howard Hughes Medical Institute (HHMI)

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Frequency dynamics predict viral fitness, antigenic relationships and epidemic growth
Figgins, M. D., Bedford, T.
10.1101/2024.12.02.24318334 — Posted: 2026-01-29
Spyglass: a framework for reproducible and shareable neuroscience research
Lee, K. H., Denovellis, E. L., Ly, R., Magland, J., Soules, J., Comrie, A. E., Gramling, D. P., Guidera, J. A., Nevers, R., Adenekan, P., Brozdowski, C., Bray, S. R., Monroe, E., Bak, J. H., Coulter, M., Sun, X., Broyles, E., Shin, D., Chiang, S., Holobetz, C., Tritt, A., Ruebel, O., Nguyen, T., Yatsenko, D., Chu, J., Kemere, C., Garcia, S., Buccino, A., Frank, L. M.
10.1101/2024.01.25.577295 — Posted: 2026-01-29
SAGA1 and SAGA2 localize the starch sheath to the pyrenoid in Chlamydomonas reinhardtii
Crans, V. L., Burton, M. I., Garde, A., Wang, L., Jonikas, M. C.
10.64898/2026.01.27.702031 — Posted: 2026-01-29
Social sensing of infection reprograms peripheral immunity in healthy mice
Ademolue, T. W., Pernas, L. F.
10.64898/2026.01.28.702380 — Posted: 2026-01-29
Molecular determinants of antibody-mediated priming to enhance detection of ctDNA
Tabrizi, S., Sullivan, C., Chakraborty, K., Martin-Alonso, C., An, Z., Gao, L., Kim, D. M., Patel, S. K., Blewett, T., Rhoades, J., Liu, R., Patel, S., Xiong, K., Crnjac, A., Bhatia, S. N., Adalsteinsson, V. A., Love, J. C.
10.64898/2026.01.27.701975 — Posted: 2026-01-29
MDA5 multimerization on LINE RNA drives pathogenic extracellular immune complexes in autoimmunity
Hsu, T. Y.-T., Wang, X., Isayama, Y., Jung, V., Zhang, J., van Gompel, E., Maadadi, H., Torres, C., Shimazaki-Takahashi, A., Kurihara, N., Kondo, M., Galesic, M., Notarnicola, A., Sultana, S., Maeda, A., Vleugels, R. A., Dellaripa, P. F., Yamashita, T., Ito, Y., Awaji, K., Kotani, H., Matsuda, K. M., Horuluogu, B., Grönwall, C., Joshua, V., Ukai, Y., Hosomi, N., Wagner, D. D., Lundberg, I. E., Kato, K., Hur, S.
10.64898/2026.01.27.702129 — Posted: 2026-01-28
A molecularly defined basalo-prefrontal-thalamic circuit regulates sensory and affective dimensions of pain in male mice
Xie, G., Liu, Y., Qi, X., Bhattacherjee, A., Zhang, C., Zhang, Y.
10.1101/2025.08.22.671771 — Posted: 2026-01-28
Leptin Receptor+ cells create a perisinusoidal niche for thrombopoiesis in the bone marrow by synthesizing CXCL14
Xue, y., Merchant, S., Reyes, A., Luo, M., Zhang, R., Tippetts, T., Grabowski, G., Ngo, T., Zhang, Y., Shang, Z., Jiang, N., Jeffery, E., Li, Y., Wei, T., Gu, W., Du, L., DeBerardinis, R. J., Dean, K. M., Mathews, T. P., Lucas, D. P., Zhao, Z., Morrison, S. J.
10.64898/2026.01.27.702029 — Posted: 2026-01-28
De novo design of phosphotyrosine peptide binders
Bauer, M. S., Zhang, J. Z., Wu, K., Lee, G. R., Coventry, B., Silvestri, I. M., Klupt, K. A., Shi, J., Brent, R. I., Li, X., Moller, C., Roullier, N., Vafeados, D. K., Kalvet, I., Skotheim, R. K., Zhu, S., Motmaen, A., Herrmann, L. C., Sturmfels, P., Tischer, D., Altae-Tran, H., Juergens, D., Krishna, R., Ahern, W., Yim, J., Bera, A. K., Kang, A., Joyce, E., Lu, A., Stewart, L., DiMaio, F., Mudumbi, K. C., Baker, D.
10.1101/2025.09.29.678898 — Posted: 2026-01-28
T cell engagers control solid tumors through clonal replacement and IL2-driven effector differentiation of CD8 T-cells
Obenaus, M., Poupault, C. L., McGinnis, C. S., Prange, C., Jiang, H., Su, L. L., Chen, X., Miao, Z., Muldoon, J. J., Yao, W., Waghray, D., Sun, Q., Eyquem, J., Hernandez-Lopez, R. A., Satpathy, A. T., Sage, J., Garcia, K. C.
10.64898/2025.12.04.692214 — Posted: 2026-01-27

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