Channel:  The Howard Hughes Medical Institute (HHMI)

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Structural Definition of Neutralizing Epitopes within and around the HKU1 Receptor-binding Site Reveals Cell Context-Dependent Neutralization
Joseph, J., Wang, L., Vasquez, S., Su, C.-M., Wrapp, D., Rosen, O., Abiona, O. M., Dzuvor, C. K. O., Kirchdoerfer, R. N., Moak, S. P., Sheahan, T. P., Hammond, C., Shi, W., Kong, W.-P., Zhang, Y., Eso, M. R., Brown, A. J., Dangi, T., Penaloza-MacMaster, P., Ward, A. B., Baric, R., McLellan, J. S., Pierson, T. C., Mascola, J., Graham, B. S., Yassine, H. M., Saeed, M., Barnes, C. O., Corbett-Helaire, K. S.
10.1101/2025.10.29.685445 — Posted: 2026-08-19
Genetic innovation in coronaviruses driven by a viral nuclease
Bianco, C., Stabell, A. C., Lodha, M., Aldis, M., Tartell, M. A., Hatziioanou, T., Bieniasz, P. D.
10.64898/2026.08.15.744938 — Posted: 2026-08-19
VTA dopamine neuron activity produces spatially organized stimulus and action value representations through conditioned reinforcement
Pan-Vazquez, A., Zimmerman, C. A., McMannon, B., Fabre, J. M. J., Louka, M., Jia, T., Sagiv, Y., West, S. J., Faulkner, M., International Brain Laboratory, , Dayan, P., Witten, I. B.
10.1101/2025.11.04.685995 — Posted: 2026-08-19
Cryo-EM of a nucleotide-polymerizing ribozyme enables its predictive improvement
Szokoli, D., Hingey, J., Wu, V., Haack, D. B., Spellmon, N., Rudolfs, B., Mancino, A., Yu, Z., Toor, N., Das, R.
10.64898/2026.08.14.744467 — Posted: 2026-08-19
Kinetochore diversification in Naegleria reveals plasticity in the kinetochore-microtubule interface
Kennard, A. S., Larkin, E. M., Ritz, J. M., Moodie, B., Fritz-Laylin, L.
10.64898/2026.08.18.745565 — Posted: 2026-08-19
The south Congo Basin was critical to Bantu settlement of south central Africa
Choin, J., de Luna, K., Fleisher, J., Sawchuk, E., Goldstein, S., Kaliba, P., Katongo, M., Morris, A. G., Mudenda, G., Welling, M., Sirak, K., Callan, K., Iliev, L., Lawson, A. M., Michel, M., Oppenheimer, J., Qiu, L., Workman, J. N., Kearns, A., Mah, M., Soos, G., Mallick, S., Rohland, N., Thompson, J., Prendergast, M. E., Reich, D.
10.64898/2026.08.14.741591 — Posted: 2026-08-19
FlyPredictome: A structural atlas of predicted protein-protein interactions in Drosophila
Kim, A.-R., Comjean, A., Veal, A., Rodiger, J., Han, M., Hu, Y., Perrimon, N.
10.64898/2026.04.14.718529 — Posted: 2026-08-18
De novo design of autocatalytically forming intra- and intermolecular isopeptide bonds to construct rigid covalent protein assemblies
Milles, L. F., Huddy, E. B., Carr, A., Hsia, Y., Li, X., Kang, A., Sankaran, B., Bera, A. K., Baker, D.
10.64898/2026.08.13.744004 — Posted: 2026-08-18
ATP-dependent reorientation on a nucleosome primes INO80 for DNA translocation
Wu, H., Kaur, U., Li, C., Munoz, E. N., Narlikar, G. J., Cheng, Y.
10.64898/2026.08.11.744281 — Posted: 2026-08-18
Protein design to broadly reprogram engineered T cell function
Boyken, S. E., Merillat, S., Langan, R. A., Moffett, H. F., Coventry, B., Haeseleer, F., Haworth, K. G., Goreshnik, I., DeSautelle, J., Chukinas, J., Hammerson, B., Davenport, T. M., Nguyen, D., Amin, R., Yuan, S., Foight, G. W., Weitzner, B. D., Foster, A. E., Baker, D., Lajoie, M. J.
10.64898/2026.08.13.742806 — Posted: 2026-08-17

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