Channel:  The Howard Hughes Medical Institute (HHMI)

2,322 Articles

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GAP mimetic activity of pan-Ras TCI daraxonrasib synergizes with K-Ras Switch-II pocket inhibition
Pfaff, P., Shokat, K.
10.64898/2026.03.11.711097 — Posted: 2026-03-13
Antibody Mediated Diversification of Primary and Secondary Humoral Immune Responses
Schaefer-Babajew, D., Binet, L., Santos, G. S. S., Ruprecht, C., Deimel, L. P., ElTanbouly, M. A., Gharrassi, D., Lima dos Reis, G., Uhe, C., Yao, K.-H., Hernandez, B., Agrawal, P., Gazumyan, A., Stamatatos, L., Hartweger, H., Nussenzweig, M. C.
10.64898/2025.12.15.694384 — Posted: 2026-03-13
Enhancer binding kinetics explain transcription factor hub formation
Fallacaro, S., Kapoor, M., Encarnation, L., Mukherjee, A., Turner, M. A., Garcia, H. G., Mir, M.
10.1101/2025.04.07.647578 — Posted: 2026-03-12
Somatic mosaicism in amyotrophic lateral sclerosis and frontotemporal dementia identifies focal mutations associated with widespread degeneration
Zhou, Z., Kim, J., Huang, A. Y., Nolan, M., Park, J., Doan, R., Shin, T., Miller, M. B., Bae, M., Zhao, B., Kim, J., Chhouk, B., Morillo, K., Yeh, R. C., Kenny, C., Neil, J. E., Lee, C.-Z., Ohkubo, T., Ravits, J., Ansorge, O., Ostrow, L. W., Lagier-Tourenne, C., Lee, E. A., Walsh, C. A.
10.1101/2023.11.30.569436 — Posted: 2026-03-12
Large-scale mutational analysis uncovers molecular mechanisms governing dual RNA functions in transposons
Mortman, E. E., Sternberg, S. H.
10.64898/2026.03.11.711047 — Posted: 2026-03-12
SUMO mediates the coordinate regulation of meiotic chromosome length and crossover rate
Yun, Y., Qiao, H., White, M., Sandhu, S., Qiu, W., Bourne, S., Deshpande, A., Bhatt, S., Sharma, A., Bailey, L., Tran, H., Prasada Rao, H., Hunter, N.
10.64898/2026.03.10.710713 — Posted: 2026-03-11
m6A-dependent microRNA binding to chromatin-associated RNA for transcriptional activation
Zhong, Y., Zheng, L., Li, J., Liu, C., Wei, J., Ye, C., Dou, X., Liu, B., Barbosa, E., Yang, F., Pitroda, S., Chen, M., Weichselbaum, R., He, C.
10.64898/2026.02.02.703428 — Posted: 2026-03-11
Interdependent RNA structural motifs at the 3'-terminus of the West Nile virus genome regulate viral growth
Tsao, L. H., Brackney, D. E., Pyle, A. M.
10.64898/2026.03.11.711107 — Posted: 2026-03-11
Peaceful Queen Succession in the Naked Mole Rat
Abeywardena, S. C., Schraibman, A. M., Delgado Cuevas, V., Ayres, J. S.
10.64898/2026.01.09.698689 — Posted: 2026-03-11
Luminal epithelium remodeling underlies endometrial regeneration during menstruation and pregnancy
Ang, C. J., Gable, J. J. R., Lyons, K. C., Miguel Whelan, E., Cevrim, C., Skokan, T. D., Bennetts, S. G., Manetta, B. D., Kaage, A. M., Mopure, D., Breznik, A., Murphy, P. L., Goldstein, A. E., Sanchis-Calleja, F., Spencer, T. E., Kelleher, A. M., McKinley, K. L.
10.64898/2026.03.08.710375 — Posted: 2026-03-10

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