Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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Design of facilitated dissociation enables control over cytokine signaling duration
Broerman, A. J., Pollmann, C., Lichtenstein, M. A., Jackson, M. D., Tessmer, M. H., Ryu, W. H., Abedi, M. H., Sahtoe, D. D., Allen, A., Kang, A., De La Cruz, J., Brackenbrough, E., Sankaran, B., Bera, A. K., Zuckerman, D. M., Stoll, S., Praetorius, F., Piehler, J., Baker, D.
10.1101/2024.11.15.623900 — Posted: 2024-11-16
Multiplexed perturbation of yew reveals cryptic proteins that enable a total biosynthesis of baccatin III and Taxol precursors
McClune, C. J., Liu, J. C.-T., Wick, C., De La Pena, R., Lange, B. M., Fordyce, P. M., Sattely, E. S.
10.1101/2024.11.06.622305 — Posted: 2024-11-16
Biochemical principles of miRNA targeting in flies
Vega-Badillo, J., Zamore, P., Jouravleva, K.
10.1101/2024.11.16.623948 — Posted: 2024-11-16
Self-restrained sex chromosome drive through sequential asymmetric meiosis
Meng, X., Yamashita, Y. M. M.
10.1101/2024.11.14.623699 — Posted: 2024-11-15
Real-time volumetric imaging of cells and molecules in deep tissues with Takoyaki ultrasound
Lee, S., Wu, D., Malounda, D., Rabut, C., Shapiro, M. G.
10.1101/2024.11.14.623368 — Posted: 2024-11-15
Schistosome esophageal gland factor MEG-8.2 drives host cell lysis and interacts with host immune proteins
Yadav, P., Simbassa, S. B., Sloan, R., Newmark, P. A., Lee, J.
10.1101/2024.11.15.623777 — Posted: 2024-11-15
Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model
Balak, C. D., Schlachetzki, J. C. M., Lana, A. J., West, E., Hong, C., DuGal, J., Zhou, Y., Li, B., Saisan, P., Spann, N. J., Sarsani, V., Pasillas, M. P., O'Brien, S., Gordts, P., Stevens, B., Kamme, F., Glass, C. K.
10.1101/2024.11.12.623296 — Posted: 2024-11-14
Model Based Inference of Synaptic Plasticity Rules
Mehta, Y., Tyulmankov, D., Rajagopalan, A. E., Turner, G. C., Fitzgerald, J. E., Funke, J.
10.1101/2023.12.11.571103 — Posted: 2024-11-12
Structure of the TXNL1-bound proteasome
Gao, J., Nardone, C., Yip, M. C., Chino, H., Gu, X., Mirman, Z., Rale, M. J., Paulo, J. A., Elledge, S. J., Shao, S.
10.1101/2024.11.08.622741 — Posted: 2024-11-10
Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1
Martin, A., Arkinson, C., Gee, C. L., Zhang, Z., Dong, K.
10.1101/2024.11.08.622731 — Posted: 2024-11-09

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