Channel:  The Howard Hughes Medical Institute (HHMI)

2,708 Articles

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Long-range mRNA folding shapes expression and sequence of bacterial genes
Gill, M. S., Kim, I. A., Xue, J. R., Thappeta, Y., Taggart, J. C., Li, G.-W.
10.1101/2025.11.27.690947 — Posted: 2025-11-27
Flavoaffinins, elusive cellulose-binding natural products from an anaerobic bacterium
Kountz, D. J., Yu, R., Lee, J. H., Maloney, K. N., Balskus, E. P.
10.1101/2025.02.08.637243 — Posted: 2025-11-25
A Structure-Guided Kinase-Transcription Factor Interactome Atlas Reveals Docking Landscapes of the Kinome
Kim, A.-R., Huang, K., Johnson, J. L., Yaron-Barir, T. M., Wang, K., Cantley, L. C., Hu, Y., Perrimon, N.
10.1101/2025.10.10.681672 — Posted: 2025-11-25
Memory traces bias new learning for hippocampal generalization
Qian, F. K., Li, G., Lipshutz, D., Romani, S., Magee, J. C.
10.1101/2025.11.24.690297 — Posted: 2025-11-25
Life-long behavioral screen reveals an architecture of vertebrate aging
Bedbrook, C. N., Nath, R. D., Zhang, L., Linderman, S. W., Brunet, A., Deisseroth, K.
10.1101/2025.11.21.688112 — Posted: 2025-11-24
Deconvolving SARS-CoV-2 mRNA vaccine impact on immunotherapy-related survival in a pandemic
Jee, J., Zhang, J., Lavery, J., Waters, M., Fong, C., Minn, A., Glickman, M., Panageas, K., Sawyers, C., Schultz, N.
10.1101/2025.11.21.25340753 — Posted: 2025-11-23
RNA switch model for localization and translation of the myelin basic protein mRNA
Topkar, V. V., Wu, V., Ho, L. T., Ambiel, N., Valenzuela, A., Yoshimura, K., Zuchero, J. B., Fu, M.-m., Das, R.
10.1101/2025.11.19.689361 — Posted: 2025-11-20
Targeting peptide-MHC complexes with designed T cell receptors and antibodies
Motmaen, A., Jude, K. M., Wang, N., Minervina, A., Feldman, D., Lichtenstein, M. A., Ebenezer, A., Correnti, C., Thomas, P. G., Garcia, K. C., Baker, D., Bradley, P.
10.1101/2025.11.19.689381 — Posted: 2025-11-20
Nucleotide context models outperform protein language models for predicting antibody affinity maturation
Johnson, M. M., Sung, K., Haddox, H. K., Vora, A. A., Araki, T., Victora, G. D., Song, Y. S., Fukuyama, J., Matsen, F. A.
10.1101/2025.06.16.659977 — Posted: 2025-11-20
Unconventional linkers facilitate potent stabilized coronavirus stem antibody responses following nanoparticle vaccination
Dzuvor, C. K. O., Moak, S. P., McManus, L. R., Dzordzorme, A. E., Evanson, L. R., Kim, T., Thomas, A., Adeyemi, O., Foley, V., Limaye, A., McNamara, R. P., Corbett-Helaire, K. S.
10.1101/2025.11.19.689216 — Posted: 2025-11-19

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