Channel:  Aligning Science Across Parkinson's (ASAP)

475 Articles

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LRRK2 integrates Rab and GABARAP interactions to sense and respond to distinct lysosomal stresses
Clegg, D., Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.
10.1101/2025.11.19.689251 — Posted: 2025-11-19
Pathway and gates for ATG2A-mediated lipid transport in autophagy
Cabezudo, A. C., Holzer, E., Martens, S., Hummer, G.
10.1101/2025.11.16.688672 — Posted: 2025-11-16
AutoMorphoTrack: A modular framework for quantitative analysis of organelle morphology, motility, and interactions at single-cell resolution
Bayati, A., Schumacher, J. G., Chen, X.
10.1101/2025.07.19.665650 — Posted: 2025-11-12
Insights into the regulation of VPS13 family bridge-like lipid transfer proteins from the structure of VPS13C.
Li, D., Wang, X., Hu, B., Hao, H., Hamill, S., Li, Y., Chen, G., De Camilli, P., Reinisch, K.
10.1101/2025.11.10.687702 — Posted: 2025-11-11
Reconstitution of multistep recruitment of ULK1 to membranes in autophagy
Duan, Y., Lu, Y., Paul, S., Betz, J., Wilhelm, L. P., Cook, A. S. I., Ren, X., Adriaenssens, E., Martens, S., Ganley, I., Hummer, G., Hurley, J. H.
10.1101/2025.11.07.687251 — Posted: 2025-11-09
Parkinsons disease modeling in regenerative spiny mice (Acomys dimidiatus) captures key disease-relevant behavioral, histological, and molecular signatures
Dutta, S., Pang, M., Donahue, R. R., Chou, T.-F., Seifert, A. W., Gradinaru, V.
10.1101/2025.11.06.687049 — Posted: 2025-11-08
Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease
Chocarro, J., Marana, S., Espelosin, M., Rico, A. J., Ariznabarreta, G., Lorenzo-Ramos, E., Ilarduya, M. M., Hernandez-Alcoceba, R., Chillon, M., Vila, M., Kordower, J., Schapira, A. H. V., Garcia-Osta, A., Cuadrado-Tejedor, M., Lanciego, J. L.
10.1101/2025.05.09.653000 — Posted: 2025-11-05
Sst+ GPi output neurons provide direct feedback to key nodes of the basal ganglia and drive behavioral flexibility.
Weglage, M., Aehrlund Richter, S., Contestabile, A., Skara, V., Fuzik, J., Santos, I., Lazaridis, I., Meletis, K.
10.1101/2022.03.16.484460 — Posted: 2025-10-30
Extracellular space diffusion modelling identifies distinct functional advantages of archetypical glutamatergic and GABAergic synapse geometries
Gimenez, P., Shakya, R. T., Santamaria, F., Tonnesen, J.
10.1101/2025.10.29.685288 — Posted: 2025-10-29
Utilizing Intraindividual Cognitive Variability to Predict Early Neuronal Synuclein Disease Progression
Combs, H. L., Kurth, R., Nair, A., York, M. K., Weintraub, D., Lafontant, D.-E., Caspell-Garcia, C., and the Parkinson's Progression Markers Initiative
10.1101/2025.10.21.25338482 — Posted: 2025-10-23

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