Channel:  Aligning Science Across Parkinson's (ASAP)

403 Articles

PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation
Wang, S., Baumert, R., Sejourne, G., Sivadasan Bindu, D., Dimond, K., Sakers, K., Vazquez, L., Moore, J. L., Tan, C. X., Takano, T., Rodriguez, M. P., Brose, N., Bradley, L., Lessing, R., Soderling, S. H., La Spada, A. R., Eroglu, C.
10.1101/2023.04.09.536178 — Posted: 2025-04-29
T cell responses towards PINK1 and α-synuclein are elevated in prodromal Parkinson's disease
Johansson, E., Freuchet, A., Williams, G. P., Michealis, T., Frazier, A., Litvan, I., Goldman, J. G., Alcalay, R. N., Standaert, D. G., Amara, A. W., Stover, N., Fon, E. A., Postuma, R. B., Sidney, J., Sulzer, D., Lindestam Arlehamn, C. S., Sette, A.
10.1101/2025.04.21.649871 — Posted: 2025-04-24
Differential memory enrichment of cytotoxic CD4 T cells in Parkinson's disease patients reactive to α-synuclein
Freuchet, A., Johansson, E., Frazier, A., Litvan, I., Goldman, J. G., Alcalay, R. N., Sulzer, D., Lindestam Arlehamn, C. S., Sette, A.
10.1101/2025.04.21.649867 — Posted: 2025-04-24
ATG2A engages Rab1a and ARFGAP1 positive membranes during autophagosome biogenesis
Fuller, D. M., Wu, Y., Schueder, F., Rasool, B., Nag, S., Korfhage, J. L., Garcia-Milian, R., Melnyk, K. D., Bewersdorf, J., De Camilli, P., Melia, T.
10.1101/2025.03.24.645038 — Posted: 2025-04-17
AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact
Padman, B. S., Lindblom, R. S. J., Lazarou, M.
10.1101/2024.11.20.624606 — Posted: 2025-04-16
Does COMT Play a Role in Parkinson's Disease Susceptibility Across Diverse Ancestral Populations?
Martin-Bornez, M., Shar, N., Nour, M. A., Murphy, D., Elsayed, I., N, M. S., Nwaokorie, F., Olusanya, A., Kuznetsov, N., Bandres-Ciga, S., Noyce, A. J., Iwaki, H., Jones, L., Gomez-Garre, P., Mir, P., The Global Parkinson's Genetics Program (GP2), , Perinan, M. T.
10.1101/2025.04.11.25325572 — Posted: 2025-04-11
Activity-Dependent Remodeling of Corticostriatal Axonal Boutons During Motor Learning
Sheng, M., Lu, D., Sheng, K., Ding, J.
10.1101/2024.06.10.598366 — Posted: 2025-04-09
Standardised TruAI automated quantification of intracellular neuromelanin granules in human brain tissue sections
Filimontseva, A., Cuadros, T., Chatterton, Z., Compte, J., Fu, Y., Vila, M., Halliday, G.
10.1101/2025.01.20.633975 — Posted: 2025-04-07
Astrocytic polyamine transport by ATP13A4 tunes excitatory synaptic transmission
van Veen, S., Irala, D., Sakers, K., Savage, J., Sejourne, G., Bindu, D. S., Ausloos, E., Dhondt, H., Schoonvliet, N., Van den Haute, C., Van Asselberghs, J., Weirda, K., Baekelandt, V., Platzer, K., Rostasy, K., Yap, K. L., Eggermont, J., Holt, M., Eroglu, C., Vangheluwe, P.
10.1101/2025.04.04.25325117 — Posted: 2025-04-06
HyDrop v2: Scalable atlas construction for training sequence-to-function models
Dickmänken, H., Wojno, M., Theunis, K., Eksi, E. C., Mahieu, L., Christiaens, V., Kempynck, N., De Rop, F. V., Roels, N., Spanier, K. I., Vandepoel, R., Hulselmans, G. J., Poovathingal, S., Aerts, S.
10.1101/2025.04.02.646792 — Posted: 2025-04-05

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