Channel:  Aligning Science Across Parkinson's (ASAP)

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Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved TBM motif
Waschbuesch, D., Pal, P., Nirujogi, R. S., Cavin, M., Singh, J., Alessi, D. R., Khan, A. R.
10.1101/2025.08.19.670962 — Posted: 2025-08-24
α-Synuclein driven cell susceptibility in Parkinson's disease
Breiter, J. C., Beckwith, J. S., Brock, E. E., Lachica, J., Toomey, C. E., Fu, B., Ryten, M., Weiss, L. E., Wood, N. W., Gandhi, S., Vendruscolo, M., Lee, S. F.
10.1101/2025.08.19.670819 — Posted: 2025-08-23
Towards Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale
Fan, Z., Searle, G. E., Rizzo, G., Albani, J., Cella, P. A., Comley, R. A., Klein, G., Passamonti, L., Salinas, C. A., Schwarz, A. J., Iaccarino, L., Tamagnan, G., Eberling, J. L., Marek, K., Seibyl, J. P., Gunn, R. N.
10.1101/2025.08.19.25333801 — Posted: 2025-08-21
Patch deconvolution for Fourier light-field microscopy
Fu, B., Jones, C. L., Heraghty, D., Yang, S., O'Brien-Ball, C., Junghans, V., Yang, H., Knowles, T., Weiss, L. E., Fernandes, R. A., Lee, S. F.
10.1101/2025.06.13.659385 — Posted: 2025-08-20
Neuromodulator control of energy reserves in dopaminergic neurons
Pulido, C., Gentry, M. S., Ryan, T. A.
10.1101/2025.08.19.671144 — Posted: 2025-08-19
A lipid transfer-dependent feedback loop activates ATG9A compartments in autophagy initiation
Holzer, E., Sawa-Makarska, J., Bernklau, D., Romanov, J., Schuschnig, M., Martens, S.
10.1101/2025.08.16.670665 — Posted: 2025-08-18
Standardised TruAI automated quantification of intracellular neuromelanin granules in human brain tissue sections
Filimontseva, A., Cuadros, T., Chatterton, Z., Burke, A., Ansari Mahabadian, A., Compte, J., Fu, Y., Vila, M., Halliday, G.
10.1101/2025.01.20.633975 — Posted: 2025-08-14
Genome-wide association analyses reveal susceptibility variants linked to Parkinson's disease in the South African population using inferred global and local ancestry
Step, K., Leal, T. P., Waldo, E., Madula, L., Swart, Y., Hernandez, C. F., Kim, J. J., Bandres Ciga, S., Global Parkinson's Genetics Program, , Mata, I., Bardien, S.
10.1101/2025.08.01.25331910 — Posted: 2025-08-02
Elevated brain α-synuclein, phosphorylated-tau, and oxidative stress in mice that survived influenza A pneumonitis
Lunn, M. O., Lengacher, N. A., Hake-Volling, Q., Tomlinson, J. J., aSCENT-PD Investigators, , Brown, E. G., Schlossmacher, M. G.
10.1101/2025.07.31.667659 — Posted: 2025-08-01
LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson's disease model
Blasco-Agell, L., Espinal, M. P., Testa, V., Roch, G., Montero-Mu, J., Fern, I., Baruffi, V., Gonzalez-Sepulveda, M., Richaud-Patin, Y., Jim, S., Cuadros, T., Cladera-Sastre, J. M., Compte, J., Manglano-Artu"n"edo, Z., Ventura, S., Otero, M. J., Tolosa, E., Raya, A., Vila, M., Consiglio, A.
10.1101/2024.10.07.616997 — Posted: 2025-07-30

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