Channel:  Aligning Science Across Parkinson's (ASAP)

451 Articles

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Astrocytic polyamine transport by ATP13A4 tunes excitatory synaptic transmission
van Veen, S., Irala, D., Sakers, K., Savage, J., Sejourne, G., Bindu, D. S., Ausloos, E., Dhondt, H., Schoonvliet, N., Van den Haute, C., Van Asselberghs, J., Weirda, K., Baekelandt, V., Platzer, K., Rostasy, K., Yap, K. L., Eggermont, J., Holt, M., Eroglu, C., Vangheluwe, P.
10.1101/2025.04.04.25325117 — Posted: 2025-04-06
HyDrop v2: Scalable atlas construction for training sequence-to-function models
Dickmänken, H., Wojno, M., Theunis, K., Eksi, E. C., Mahieu, L., Christiaens, V., Kempynck, N., De Rop, F. V., Roels, N., Spanier, K. I., Vandepoel, R., Hulselmans, G. J., Poovathingal, S., Aerts, S.
10.1101/2025.04.02.646792 — Posted: 2025-04-05
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM
Hanna, M. G., Rodriguez Cruz, H. O., Fujise, K., Wu, Y., Xu, C. S., Pang, S., Zhuoning, L., Monetti, M., De Camilli, P.
10.1101/2024.09.28.615015 — Posted: 2025-04-03
CREsted: modeling genomic and synthetic cell type-specific enhancers across tissues and species
Kempynck, N., De Winter, S., Blaauw, C. H., Konstantakos, V., Dieltiens, S., Eksi, E. C., Bercier, V., Taskiran, I. I., Hulselmans, G., Spanier, K., Christiaens, V., Van Den Bosch, L., Mahieu, L., Aerts, S.
10.1101/2025.04.02.646812 — Posted: 2025-04-03
iNeurons are sweet, maybe too sweet? Exploring the impact of media composition on PINK1-dependent mitophagy
O'Callaghan, B., Melandri, D., Soltic, D., Cosker, K., Soutar, M. P. M., Plun-Favreau, H.
10.1101/2025.04.01.646648 — Posted: 2025-04-03
Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort
Schumacher, J. G., Zhang, X., Macklin, E. A., Wang, J., Bayati, A., Dijkstra, J. M., Watanabe, H., Schwarzschild, M. A., Cortese, M., Zhang, X., Chen, X.
10.1101/2024.09.27.24311107 — Posted: 2025-04-02
In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment
Rose, K., Herrmann, E., Kakudji, E. V., Lizarrondo, J., Celebi, A. Y., Wilfling, F., Lewis, S. C., Hurley, J. H.
10.1101/2025.03.24.645001 — Posted: 2025-03-25
Soluble Immune Factor Profiles in Blood and CSF Associated with LRRK2 Mutations and Parkinson's Disease
Jaffery, R., Zhao, Y., Ahmed, S., Schumacher, J. G., Ahn, J., Shi, L., Wang, Y., Tan, Y., Chen, K., Tawbi, H., Wang, J., Schwarzschild, M. A., Peng, W., Chen, X.
10.1101/2025.03.20.644460 — Posted: 2025-03-24
PPM1M, a LRRK2-counteracting, phosphoRab12-preferring phosphatase with potential link to Parkinsons disease
Chiang, C. Y., Pratuseviciute, N., Lin, Y.-E., Adhikari, A., Yeshaw, W. M., Flitton, C., Sherpa, P. L., Tonelli, F., Rektorova, I., Lynch, T., Siuda, J., Rudzinska-Bar, M., Pulyk, O., Bauer, P., Beetz, C., Dickson, D. W., Ross, O. A., Wszolek, Z., Klein, C., Zimprich, A., Alessi, D. R., Sammler, E. M., Pfeffer, S. R.
10.1101/2025.03.19.644182 — Posted: 2025-03-19
Validation of a Mitochondrial Polygenic Score for Parkinson's Disease
Ooi, J. C. E., Tay, Y. W., Tan, A. H., Lin, C.-H., Brolin, K. A., Laabs, B.-H., Sendel, S., König, I. R., Caliebe, A., Gabbert, C., Andersh, K. M., Jones, L., Lange, L. M., Fiske, B., Sue, C., Klein, C., Trinh, J., Lüth, T., Global Parkinson's Genetics Program (GP2)
10.1101/2025.03.18.25323898 — Posted: 2025-03-19

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