Channel:  Aligning Science Across Parkinson's (ASAP)

513 Articles

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A single Citrobacter rodentium infection in Pink1 knockout and wild type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss
Mukherjee, S., Grouza, V., Tchung, A., Even, A., Yaqubi, M., Tuznik, M., Cannon, T., Recinto, S. J., Gavino, C., Bourque, M.-J., Giguere, N., McBride, H. M., Desjardins, M., Gruenheid, S., Stratton, J. A., Rudko, D. A., Trudeau, L.-E.
10.1101/2024.12.24.630165 — Posted: 2026-06-17
Q-DOAS: A Proximity Quenching Assay for Real-Time Detection of Early Protein Aggregation Events
Kleczko, K. M., Gestaut, D., Dobbins, S., Abramovich, J., Sitron, C. S., Li, L., Chan, R., Wang, N., Yang, X. W., Hartl, F.-U., Frydman, J.
10.64898/2026.06.16.732424 — Posted: 2026-06-17
Striatal ensembles specify and control ongoing actions at fine motorresolution
Rodrigues-Vaz, I., Athalye, V. R., Rodrigues, H. F. M., Peterka, D. S., Costa, R. M.
10.64898/2025.12.03.692128 — Posted: 2026-06-12
Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
Vatsa, N., Brynildsen, J. K., Goralski, T. M., Kurgat, K., Meyerdirk, L., Breton, L., DeWeerd, D., Brasseur, L., Turner, L., Becker, K., Gallik, K. L., Isaguirre, C., Sheldon, R. D., Bassett, D. S., Henderson, M. X.
10.1101/2024.10.22.619411 — Posted: 2026-06-12
Structural Mechanism and Cellular Restriction of Tau Seeding from Endolysosomes
Herrmann, E., Tan, S., Rose, K. M., Hooy, R. M., Hurley, J. H.
10.64898/2026.06.08.731026 — Posted: 2026-06-10
A genome-wide association study of young onset Parkinson's disease in European ancestry
Lie, I. H., van Wetering, J., Valori, M., Brolin, K. A., Step, K., Schulte, C., Iwaki, H., Bandres-Ciga, S., Leonard, H. L., Sharma, M., International Parkinson's Disease Genomics Consortium, , Global Parkinson's Genetics Program, , Singleton, A., Pihlstrom, L.
10.64898/2026.06.03.26354799 — Posted: 2026-06-04
Structural basis for regulation of the proteasome 20S core particle by the Parkinsonism-associated proteins FBXO7 and PI31
Adolf, F., Goodall, E. A., Singh, E., von Gronau, S., Fermin Perez, E., Fung, D., Mueller, B. S., Paulo, J. A., Hanna, J., Harper, J. W., Schulman, B. A.
10.64898/2026.05.28.728263 — Posted: 2026-06-04
Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency
Cascalho, A., Sati, A., Dhondt, H., Schoonvliet, N., Kaempf, N., Coccia, E., Mamalaki, A., Behrens, M. I., Brüggemann, N., Glatzel, M., Baekelandt, V., Klein, C., Eggermont, J., Verstreken, P., Blanchard, J., Vangheluwe, P.
10.64898/2026.05.23.26353575 — Posted: 2026-06-04
Emergence of Task-Related Motor Cortical Dysfunction in Mice with Progressive Parkinsonism
Chehade, H. D., Berezhnoi, D., Somavarapu, S., Wang, Z., Jiang, J., Chen, L., Risk, B. B., Wichmann, T., Chu, H.-Y.
10.64898/2026.05.29.728524 — Posted: 2026-06-02
Genetic screening and metabolomics identify glial adenosine metabolism as a therapeutic target in Parkinson's disease
Sodders, M. J., Avila-Pacheco, J., Okorie, E. C., Tahmasebidehkordi, H., Marathi, A., Kumari, N., Lakhani, M., Schiro, A., Shen, M., Sriram, N., Bullock, K., Pierce, K., Dennis, C., Jeanfavre, S., Sarkar, S., Weykopf, B., Muratore, C., Young-Pearse, T. L., Mazzulli, J., Scherzer, C. R., Clish, C., Olsen, A. L.
10.1101/2024.05.15.594309 — Posted: 2026-06-01

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