Channel:  Aligning Science Across Parkinson's (ASAP)

463 Articles

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LRRK2 integrates Rab and GABARAP interactions to sense and respond to distinct lysosomal stresses
Clegg, D., Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.
10.1101/2025.11.19.689251 — Posted: 2025-11-19
A Multimodal Atlas Reveals the Anatomical Distribution of Medium Spiny Neuron Subtypes and a Novel RGS6+ Population in the Primate Striatum
Abdelhady, G., Brull, O. R., He, J., Lin, M. K., Galvan, A., Pfenning, A. R., Bostan, A. C., Stauffer, W. R.
10.1101/2025.11.16.688724 — Posted: 2025-11-19
Multi-omics reveal critical differentiation target for Parkinsons' Disease-vulnerable midbrain dopaminergic neurons
Garcia Swinburn, R., Lyu, G., Kreutzmann, J. C., Xiong, A., Kojima, R., Abaurre, C., Tremolanti, C., Gellhaar, S., Uhlen, P., Svenningsson, P., Castelo Branco, G., Dagliyan, O., Salto, C., Arenas, E.
10.1101/2025.06.18.660098 — Posted: 2025-11-17
Pathway and gates for ATG2A-mediated lipid transport in autophagy
Cabezudo, A. C., Holzer, E., Martens, S., Hummer, G.
10.1101/2025.11.16.688672 — Posted: 2025-11-16
AutoMorphoTrack: A modular framework for quantitative analysis of organelle morphology, motility, and interactions at single-cell resolution
Bayati, A., Schumacher, J. G., Chen, X.
10.1101/2025.07.19.665650 — Posted: 2025-11-12
Insights into the regulation of VPS13 family bridge-like lipid transfer proteins from the structure of VPS13C.
Li, D., Wang, X., Hu, B., Hao, H., Hamill, S., Li, Y., Chen, G., De Camilli, P., Reinisch, K.
10.1101/2025.11.10.687702 — Posted: 2025-11-11
Reconstitution of multistep recruitment of ULK1 to membranes in autophagy
Duan, Y., Lu, Y., Paul, S., Betz, J., Wilhelm, L. P., Cook, A. S. I., Ren, X., Adriaenssens, E., Martens, S., Ganley, I., Hummer, G., Hurley, J. H.
10.1101/2025.11.07.687251 — Posted: 2025-11-09
Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease
Chocarro, J., Marana, S., Espelosin, M., Rico, A. J., Ariznabarreta, G., Lorenzo-Ramos, E., Ilarduya, M. M., Hernandez-Alcoceba, R., Chillon, M., Vila, M., Kordower, J., Schapira, A. H. V., Garcia-Osta, A., Cuadrado-Tejedor, M., Lanciego, J. L.
10.1101/2025.05.09.653000 — Posted: 2025-11-05
Sst+ GPi output neurons provide direct feedback to key nodes of the basal ganglia and drive behavioral flexibility.
Weglage, M., Aehrlund Richter, S., Contestabile, A., Skara, V., Fuzik, J., Santos, I., Lazaridis, I., Meletis, K.
10.1101/2022.03.16.484460 — Posted: 2025-10-30
Extracellular space diffusion modelling identifies distinct functional advantages of archetypical glutamatergic and GABAergic synapse geometries
Gimenez, P., Shakya, R. T., Santamaria, F., Tonnesen, J.
10.1101/2025.10.29.685288 — Posted: 2025-10-29

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