Channel:  Aligning Science Across Parkinson's (ASAP)

515 Articles

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Structural basis for regulation of the proteasome 20S core particle by the Parkinsonism-associated proteins FBXO7 and PI31
Adolf, F., Goodall, E. A., Singh, E., von Gronau, S., Fermin Perez, E., Fung, D., Mueller, B. S., Paulo, J. A., Hanna, J., Harper, J. W., Schulman, B. A.
10.64898/2026.05.28.728263 — Posted: 2026-06-04
A genome-wide association study of young onset Parkinson's disease in European ancestry
Lie, I. H., van Wetering, J., Valori, M., Brolin, K. A., Step, K., Schulte, C., Iwaki, H., Bandres-Ciga, S., Leonard, H. L., Sharma, M., International Parkinson's Disease Genomics Consortium, , Global Parkinson's Genetics Program, , Singleton, A., Pihlstrom, L.
10.64898/2026.06.03.26354799 — Posted: 2026-06-04
Emergence of Task-Related Motor Cortical Dysfunction in Mice with Progressive Parkinsonism
Chehade, H. D., Berezhnoi, D., Somavarapu, S., Wang, Z., Jiang, J., Chen, L., Risk, B. B., Wichmann, T., Chu, H.-Y.
10.64898/2026.05.29.728524 — Posted: 2026-06-02
Genetic screening and metabolomics identify glial adenosine metabolism as a therapeutic target in Parkinson's disease
Sodders, M. J., Avila-Pacheco, J., Okorie, E. C., Tahmasebidehkordi, H., Marathi, A., Kumari, N., Lakhani, M., Schiro, A., Shen, M., Sriram, N., Bullock, K., Pierce, K., Dennis, C., Jeanfavre, S., Sarkar, S., Weykopf, B., Muratore, C., Young-Pearse, T. L., Mazzulli, J., Scherzer, C. R., Clish, C., Olsen, A. L.
10.1101/2024.05.15.594309 — Posted: 2026-06-01
AAV tools enable functional modulation and readout of central and peripheral nervous systems in spiny mice
Chung, J. H., Donahue, R. R., Griffiths, J. A., Fan, Y., Lin, C., Chen, X., Dutta, S., Mazmanian, S., Seifert, A. W., Gradinaru, V.
10.64898/2026.05.08.723863 — Posted: 2026-05-29
In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
Basiashvili, T., Hutchings, J., Chen, S., Karasmanis, E. P., Flaherty, W. A., Leschziner, A. E., Villa, E.
10.64898/2025.12.18.694444 — Posted: 2026-05-28
STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.
Fahmy, A. M., Ahmadi, A., Lanoix, J., Cannon, T., Badr Elemeery, m. N., Hernandez Paredes, C., Barrette, B., Bonneil, E., Zhong Xu, Y., Ibrahim, M., Arango-Duque, G., Audemard, E. O., Lemieux, S., Chevet, E., Schurr, E., Pierre, P., Gruenheid, S., Thibault, P., McBride, H. M., Desjardins, M.
10.64898/2026.05.25.727656 — Posted: 2026-05-28
The mitochondrial unfolded protein response in human microglia disrupts neuronal-glial communication and promotes senescence
Perez Jimenez, M. J., Lam, A., Weissleder, C., Bertoli, F., Raji, H., Bosch, M., Nemazanyy, I., Kalb, S., Kehili, M., Hirschberg, I., Brunetti, D., Heckenbach, I., Scheibye-Knudsen, M., Deleidi, M.
10.1101/2024.09.03.610925 — Posted: 2026-05-27
Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum
Miller-Hansen, A. J., Zhu, M., Kovaleski, R. F., Demir, B., Lerner, T. N.
10.64898/2026.05.08.723861 — Posted: 2026-05-23
ATG2A interacts with RAB1A and ARFGAP1 positive membranes during autophagosome biogenesis
Fuller, D. M., Wu, Y., Schueder, F., Rasool, B., Nag, S., Korfhage, J. L., Garcia-Milian, R., Melnyk, K. D., Bewersdorf, J., De Camilli, P., Melia, T.
10.1101/2025.03.24.645038 — Posted: 2026-05-19

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