Channel:  Aligning Science Across Parkinson's (ASAP)

425 Articles

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Validation of a Mitochondrial Polygenic Score for Parkinson's Disease
Ooi, J. C. E., Tay, Y. W., Tan, A. H., Lin, C.-H., Brolin, K. A., Laabs, B.-H., Sendel, S., König, I. R., Caliebe, A., Gabbert, C., Andersh, K. M., Jones, L., Lange, L. M., Fiske, B., Sue, C., Klein, C., Trinh, J., Lüth, T., Global Parkinson's Genetics Program (GP2)
10.1101/2025.03.18.25323898 — Posted: 2025-03-19
PPM1M, a LRRK2-counteracting, phosphoRab12-preferring phosphatase with potential link to Parkinsons disease
Chiang, C. Y., Pratuseviciute, N., Lin, Y.-E., Adhikari, A., Yeshaw, W. M., Flitton, C., Sherpa, P. L., Tonelli, F., Rektorova, I., Lynch, T., Siuda, J., Rudzinska-Bar, M., Pulyk, O., Bauer, P., Beetz, C., Dickson, D. W., Ross, O. A., Wszolek, Z., Klein, C., Zimprich, A., Alessi, D. R., Sammler, E. M., Pfeffer, S. R.
10.1101/2025.03.19.644182 — Posted: 2025-03-19
Novel Parkinson's Disease Genetic Risk Factors Within and Across European Populations
The Global Parkinson's Genetics Program (GP2), , Leonard, H. L.
10.1101/2025.03.14.24319455 — Posted: 2025-03-17
17q21.31 locus regulates Parkinson's disease relevant pathways through KANSL1 activity
Hicks, A. R., O'Callaghan, B., Brenton, J. W., Grant-Peters, M., Fairbrother-Browne, A., Rocamora Perez, G., Loh, C. A., Reynolds, R. H., Gustavsson, E. K., Montgomery, K., Tsalenchuk, M., Real, R., Morris, H., Lunnon, K., Marzi, S. J., Jaunmuktane, Z., Hardy, J., Plun-Favreau, H., Ryten, M.
10.1101/2025.03.17.641409 — Posted: 2025-03-17
iSCORE-PD: an isogenic stem cell collection to research Parkinson Disease
Busquets, O., Li, H., Syed, K. M., Jerez, P. A., Dunnack, J., Bu, R. L., Verma, Y., Pangilinan, G. R., Martin, A., Straub, J., Du, Y., Simon, V. M., Poser, S., Bush, Z., Diaz, J., Sahagun, A., Gao, J., Hong, S., Hernandez, D., Levine, K. S., Booth, E. O., Blanchette, M., Bateup, H., Rio, D., Hockemeyer, D., Blauwendraat, C., Soldner, F.
10.1101/2024.02.12.579917 — Posted: 2025-03-11
Molecular and cellular signatures differentiate Parkinson's disease from Parkinson's disease with dementia
Fairbrother-Browne, A., Grant-Peters, M., Brenton, J. W., Nelvagal, H., Reynolds, R. H., Lim, Y. M., Gustavsson, E. K., Macpherson, H., Montgomery, K., Evans, J. R., Hicks, A. R., Chiraki, N., Curless, T., Real, R., Xenakis, T., Houlden, H., Morris, H. R., Gandhi, S., Wood, N. W., Hardy, J., Jaunmuktane, Z., Ryten, M.
10.1101/2025.03.04.641379 — Posted: 2025-03-11
Predicting Cerebrospinal Fluid Alpha-Synuclein Seed Amplification Assay Status from Demographics and Clinical Data
Venuto, C. S., Herbst, K., Chahine, L. M., Kieburtz, K.
10.1101/2024.08.07.24311578 — Posted: 2025-03-07
Contralateral spread of unilateral tremor in Parkinson Disease
Pasquini, J., Pavese, N., Ceravolo, R., Helmich, R. C., Deuschl, G.
10.1101/2025.02.20.25322608 — Posted: 2025-03-07
Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration
Rademacher, K. L., Doric, Z., Haddad, D., Mamaligas, A., Liao, S.-C., Creed, R., Kano, K., Chatterton, Z., Fu, Y., Garcia, J. H., Vance, V., Sei, Y., Kreitzer, A., Halliday, G., Nelson, A., Margolis, E., Nakamura, K. L.
10.1101/2024.04.05.588321 — Posted: 2025-03-04
MICROENDOSCOPIC CALCIUM IMAGING IN SUPPLEMENTARY MOTOR AREA AND PRIMARY MOTOR CORTEX OF RHESUS MACAQUES AT REST AND DURING ARM MOVEMENT
Martel, A.-C., Pittard, D., Devergnas, A., Risk, B., Nassi, J., Yu, W., Downer, J., Wichmann, T., Galvan, A.
10.1101/2024.06.20.599918 — Posted: 2025-03-04

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