Channel:  Aligning Science Across Parkinson's (ASAP)

501 Articles

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GPNMB and glycosphingolipid measurements in cerebrospinal fluid and plasma from Parkinson's disease patients in the BioFind cohort
Fernandez-Suarez, M. E., Bush, R. J., Di Biase, E., Te Vruchte, D., Priestman, D., Cortina-Borja, M., Cooper, O., Hardy, J., Hallett, P., Isacson, O., Platt, F. M.
10.64898/2026.04.09.712000 — Posted: 2026-04-13
ATP13A2 Loss of Function-Driven Polyamine Dysregulation Induces SAM Depletion and Epigenetic Astrocyte Toxicity
Coccia, E., Morrone Parfitt, G., Ijaz, S., Sati, A., Gesner, J., Perez Arevalo, A., Strong, J., Bright, A., Sohail, S., Meimoun, T., Ahfeldt, T., Vangheluwe, P., Blanchard, J.
10.64898/2026.04.02.716164 — Posted: 2026-04-06
Neural cell state modulation by PARK2 and dopaminergic neuroprotection by small molecule Parkin agonism
Gong, Y., Bayati, A., Alban, T. J., Parthasarathy, P., Zhou, F., Makarov, V., Zhao, Y., Su, C., Schumacher, J. G., Singh, V., Volpicelli-Daley, L. A., Luo, W., Durcan, T. M., Dutta, S., Schwarzschild, M. A., Johnston, J. A., Chan, T. A., Chen, X.
10.64898/2026.04.01.715918 — Posted: 2026-04-04
Rise-and-fall dynamics reveal a molecular and cellular vulnerability axis in prion-like α-synuclein propagation
Alexandersen, C. G., Brynildsen, J. K., Prigent, A., Tamborrino, M., Mantziou, A., Kurgat, K., Henderson, M. X., Bassett, D. S.
10.64898/2026.03.27.714785 — Posted: 2026-03-31
Genetic Identification of Dopamine Neurons Required for Circadian Food Anticipatory Activity in Mice
Villa, A., Trzeciak, J., Wolfe, D., Ehichioya, D., Falkenstein, J., Wong, J. T., Dimalanta, L., Kaiban, W., Dhanoa, J., Stevens, G., Garcia, F., Scarpa, L., Chalfoun, C., Zweifel, L., Awatramani, R., Palmiter, R., Darvas, M., Yamazaki, S., Steele, A.
10.64898/2026.03.27.714759 — Posted: 2026-03-31
Molecularly-guided spatial proteomics captures single-cell identity of the healthy and diseased nervous system
Dutta, S., Pang, M., Coughlin, G. M., Gudavalli, S., Roukes, M. L., Chou, T.-F., Gradinaru, V.
10.1101/2025.02.10.637505 — Posted: 2026-03-30
Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons
Chen, C., He, Q., Tombesi, G., Napier, E., Jaconelli, M., Moreno-Ramos, O., Serio, H., Naaldijk, Y., Promes, V., Schneeweis, A., Quinn, K., Nasios, C., Greggio, E., Kozorovitskiy, Y., Arango, D., Khan, A. R., Alessi, D. R., Dombeck, D. A., Hilfiker, S., Awatramani, R., Parisiadou, L.
10.1101/2025.08.28.672006 — Posted: 2026-03-28
A human lysosomal storage disorder toolkit for decoding proteome landscapes in cortical and dopaminergic-like induced neurons
Kraus, F., He, Y., Jiang, Y., Li, D., Ambaw, Y. A., Gasparoli, F. M., Paulo, J. A., Walther, T. C., Farese, R., Gygi, S. P., Wilfling, F., Harper, J. W.
10.1101/2025.10.08.681047 — Posted: 2026-03-23
Integrating Long-Read Structural Variant Analysis with single-nucleus RNA-seq to Elucidate Gene Expression Effects in Disease
Kim, K., Lin, Z., Simmons, S. K., Parker, J., Kearney, M., Liao, Z., Haywood, N., Zhang, J., Cline, M. P., Tuncali, I., Sharma, M., Serrano, G. E., Beach, T. G., Dong, X., Popic, V., Scherzer, C. R., Levin, J. Z.
10.64898/2026.03.20.713192 — Posted: 2026-03-23
TEsingle enables locus-specific transposable element expression analysis at single-cell resolution
Forcier, T., Cheng, E., Tam, O. H., Wunderlich, C., Castilla-Vallmanya, L., Jones, J. L., Quaegebeur, A., Barker, R. A., Jakobsson, J., Gale Hammell, M.
10.64898/2026.03.19.712984 — Posted: 2026-03-22

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