Channel:  Aligning Science Across Parkinson's (ASAP)

403 Articles

Sex-dimorphic effects of neuromelanin buildup in rodent nigral dopamine neurons: implications for sex-biased vulnerability in Parkinson's disease
D'Addario, S. L., Massaro Cenere, M., Cossa, F., Scaricamazza, S., Nesci, V., D'Ottavio, G., Caprioli, D., Ferri, A., Vila, M., Ledonne, A., Mercuri, N. B.
10.1101/2025.04.18.649338 — Posted: 2025-05-27
Repetitive Levodopa Treatment Drives Cell Type-Specific Striatal Adaptations Associated With Progressive Dyskinesia in Parkinsonian Mice
Paz, R. M., Ryan, M. B., Marcott, P. F., Girasole, A. E., Faryean, J., Duong, V., Sridhar, S., Nelson, A. B.
10.1101/2025.05.16.654598 — Posted: 2025-05-21
Drug Repurposing for Parkinson's Disease: A Large-Scale Multi-Cohort Study
Hu, Y., Liu, W., Waits, M., Zhao, Y., Olivero-Acosta, M. I., Zhang, L., Scherzer, C. R., Dong, X.
10.1101/2025.05.20.25327943 — Posted: 2025-05-21
Spatio-molecular analysis of primate subthalamus defines anatomical domains relevant to Parkinson disease and neuropsychiatry
Dumas, S., Francois, C., Karachi, C., Mackenzie, A.
10.1101/2025.05.21.655268 — Posted: 2025-05-21
Inflamed Microglia like Macrophages in the Central Nervous System of Prodromal Parkinson's Disease
Zhang, L., Yasumizu, Y., Deerhake, M. E., Moon, J., Buitrago-Pocasangre, N., Russo, A., Wang, H., Zhu, B., Seibyl, J. P., Reddy, V., Wang, Q., Spillantini, M. G., Posner, D. A., Clatworthy, M., Sumida, T. S., Longbrake, E. E., Cedarbaum, J. M., Hafler, D. A.
10.1101/2025.05.16.654530 — Posted: 2025-05-21
Microbiome signature of Parkinson disease in healthy and genetically at-risk individuals
Menozzi, E., Meslier, V., Ren, Y., Geiger, M., Macnaughtan, J., Avenali, M., Gilles, M., Galandra, C., Mitrotti, P., Gallo, L., Famechon, A., Lucas Del Pozo, S., Mezabrovschi, R., Koletsi, S., Loefflad, N., Yalkic, S., Limbachiya, N., Blottiere, H., Morabito, C., David, A., Quinquis, B., Pons, N., Valzania, F., Cavallieri, F., Fioravanti, V., Toschi, G., Blandini, F., Ehrlich, S. D., Almeida, M., Schapira, A. H.
10.1101/2025.05.19.25327907 — Posted: 2025-05-19
End-product inhibition of the LRRK2-counteracting PPM1H phosphatase
Adhikari, A., Tripathi, A., Chiang, C. Y., Sherpa, P. L., Pfeffer, S. R.
10.1101/2025.05.16.654599 — Posted: 2025-05-17
Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice
Xu, P., Mancuso, R. I., Leonzino, M., Zeiss, C. J., Krause, D. S., De Camilli, P.
10.1101/2025.05.09.653147 — Posted: 2025-05-13
Safety and Feasibility of Serial Lumbar Punctures: Long-term Results from the Parkinson's Progression Markers Initiative
Barbosa, W., Schneider, R. B., Choi, S. H., Marshall, M. J., Lafontant, D.-E., Caspell-Garcia, C., Coffey, C. S., Ross, J., Siderowf, A., Marek, K., Simuni, T., on behalf of The Parkinson's Progression Markers Initiative (PPMI)
10.1101/2025.05.05.25327008 — Posted: 2025-05-06
Assessment of common genetic variation in Alzheimer's and Parkinson's diseases reveals global distinction in population attributable risk
Jones, L., Cerquera-Cleves, C., Schumacher-Schuh, A. F., Makarious, M. B., Iwaki, H., Nalls, M. A., Noyce, A., Global Parkinson's Genetics Program (GP2), , Blauwendraat, C., Singleton, A., Mata, I., Cookson, M. R., Bandres-Ciga, S.
10.1101/2024.09.23.24314240 — Posted: 2025-05-05

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