Channel:  Aligning Science Across Parkinson's (ASAP)

513 Articles

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AAV tools enable functional modulation and readout of central and peripheral nervous systems in spiny mice
Chung, J. H., Donahue, R. R., Griffiths, J. A., Fan, Y., Lin, C., Chen, X., Dutta, S., Mazmanian, S., Seifert, A. W., Gradinaru, V.
10.64898/2026.05.08.723863 — Posted: 2026-05-29
In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
Basiashvili, T., Hutchings, J., Chen, S., Karasmanis, E. P., Flaherty, W. A., Leschziner, A. E., Villa, E.
10.64898/2025.12.18.694444 — Posted: 2026-05-28
STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.
Fahmy, A. M., Ahmadi, A., Lanoix, J., Cannon, T., Badr Elemeery, m. N., Hernandez Paredes, C., Barrette, B., Bonneil, E., Zhong Xu, Y., Ibrahim, M., Arango-Duque, G., Audemard, E. O., Lemieux, S., Chevet, E., Schurr, E., Pierre, P., Gruenheid, S., Thibault, P., McBride, H. M., Desjardins, M.
10.64898/2026.05.25.727656 — Posted: 2026-05-28
The mitochondrial unfolded protein response in human microglia disrupts neuronal-glial communication and promotes senescence
Perez Jimenez, M. J., Lam, A., Weissleder, C., Bertoli, F., Raji, H., Bosch, M., Nemazanyy, I., Kalb, S., Kehili, M., Hirschberg, I., Brunetti, D., Heckenbach, I., Scheibye-Knudsen, M., Deleidi, M.
10.1101/2024.09.03.610925 — Posted: 2026-05-27
Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum
Miller-Hansen, A. J., Zhu, M., Kovaleski, R. F., Demir, B., Lerner, T. N.
10.64898/2026.05.08.723861 — Posted: 2026-05-23
ATG2A interacts with RAB1A and ARFGAP1 positive membranes during autophagosome biogenesis
Fuller, D. M., Wu, Y., Schueder, F., Rasool, B., Nag, S., Korfhage, J. L., Garcia-Milian, R., Melnyk, K. D., Bewersdorf, J., De Camilli, P., Melia, T.
10.1101/2025.03.24.645038 — Posted: 2026-05-19
GPNMB and glycosphingolipid measurements in cerebrospinal fluid and plasma from Parkinson's disease patients
Fernandez-Suarez, M. E., Bush, R. J., Di Biase, E., Te Vruchte, D., Priestman, D., Cortina-Borja, M., Cooper, O., Hardy, J., Hallett, P., Isacson, O., Platt, F. M.
10.64898/2026.04.09.712000 — Posted: 2026-05-18
Elucidating the dysbiotic features of gut microbiome, interaction with the human genome, and utility as a biomarker for treatment of Parkinson disease.
Payami, H., Murchison, C. F., Antonello, G., Wallen, Z. D., Dean, M. N., Verster, A., Long, K. R., Waldron, L. D., Sampson, T. R., Standaert, D. G.
10.64898/2026.05.12.724602 — Posted: 2026-05-15
PINK1/Parkin-dependent mitophagy mediates astrocytic inflammatory responses to mitochondrial damage
Riley, J. F., Robbins, C. V., Holzbaur, E. L. F.
10.64898/2026.05.11.724378 — Posted: 2026-05-13
Interaction of G2019S LRRK2 and metabolic syndrome in a two-hit mouse model of Parkinson's disease: LRRK2-driven systemic depletion of pyrimidine nucleosides
Ma, Y., Erb, M. L., Sipple, K. A., Offerman, A. V., Niu, J., Madaj, Z. B., Fu, Z., Lau, K. H., Moore, D. J.
10.64898/2025.12.31.697225 — Posted: 2026-05-12

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