Channel:  The Howard Hughes Medical Institute (HHMI)

1,971 Articles

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In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
Basiashvili, T., Hutchings, J., Chen, S., Karasmanis, E. P., Flaherty, W. A., Leschziner, A. E., Villa, E.
10.64898/2025.12.18.694444 — Posted: 2026-02-18
A sequence-encoded promoter proximal super pause stabilizes an offline RNA polymerase II state
Vazquez Nunez, R. J., Kesha, S., Vos, S. M.
10.64898/2026.02.18.706689 — Posted: 2026-02-18
Nuclear tau aggregates inhibit RNA export and form by secondary seeding from cytosolic tau aggregates.
Decker, C., McCann, K., Lester, E., Pratt, J., Van Alstyne, M., Wang, Y., Parker, R.
10.64898/2026.02.17.706203 — Posted: 2026-02-18
Chemiluminescent probes allow for the rapid identification of colibactin-producing bacteria
Aguilar Ramos, M., Gutkin, S., David, M., Shabat, D., Balskus, E. P.
10.64898/2026.01.02.697419 — Posted: 2026-02-17
Selective control of prefrontal neural timescales by parietal cortex
Soyuhos, O., Zirnsak, M., Chaudhuri, R., Chen, X.
10.1101/2024.09.30.615928 — Posted: 2026-02-17
Identification and characterization of dietary antigens in oral tolerance
Blum, J. E., Kong, R., Schulman, E. A., Chen, F. M., Upadhyay, R., Romero-Meza, G., Littman, D. R., Fischbach, M., Nagashima, K., Sattely, E. S.
10.1101/2024.05.26.593976 — Posted: 2026-02-17
Cellular coding of ingestion in the caudal brainstem
Ly, T., Yi, X., Lee, G. R., Grove, J. C., Sibih, Y. E., Oh, Y. Y., Qiu, L., Namkung, H., Sivakumar, N., Knight, Z. A.
10.64898/2025.11.30.691333 — Posted: 2026-02-16
Rhomboid protease Rhbdl2 regulates macrophage recruitment and wound regeneration in zebrafish
Gourkanti, S., Ramakrishnan, G., Munoz, Y., Chavez, R. M., Cheung, J., Dohnalek, J., Schoen, T. J., Martin, K., Lovett-Barron, M. E., Whisenant, T., Strisovsky, K., Neal, S. E.
10.64898/2026.02.13.705804 — Posted: 2026-02-15
Murine models for triple-negative breast cancer with differential responsiveness to immunotherapy
Kalantzakos, T. J., Zhou, Y., Liu, X., Proehl, J., Durfee, C., Tamayo, I., Temiz, N. A., Troness, B., Soni, A., Gupta, H. B., Harris, R. S.
10.1101/2025.09.18.677171 — Posted: 2026-02-15
Distributed control circuits across a brain-and-cord connectome
Bates, A. S., Phelps, J. S., Kim, M., Yang, H. H., Matsliah, A., Ajabi, Z., Perlman, E., Delgado, K. M., Osman, M. A. M., Salmon, C. K., Gager, J., Silverman, B., Renauld, S., Salman, F., Patel, J., Collie, M. F., Fan, J., Pacheco, D. A., Zhao, Y., Zhang, W., Serratosa Capdevilla, L., Roberts, R. J., Munnelly, E. J., Griggs, N., Langley, H., Moya-Llamas, B., Zhang, Z., Maloney, R. T., Yu, S.-c., Sterling, A. R., Sorek, M., Kruk, K., Serafetinidis, N., Dhawan, S., Klemm, F., Brooks, P., Lesser, E., Jones, J. M., Pierce-Lundgren, S. E., Lee, S.-Y., Luo, Y., Cook, A. P., McKim, T. H., Giakoumas
10.1101/2025.07.31.667571 — Posted: 2026-02-14

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