Channel:  The Howard Hughes Medical Institute (HHMI)

1,937 Articles

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Learning millisecond protein dynamics from what is missing in NMR spectra
Wayment-Steele, H. K., El Nesr, G., Hettiarachchi, R., Kariyawasam, H., Ovchinnikov, S., Kern, D.
10.1101/2025.03.19.642801 — Posted: 2025-03-19
Nonenzymatic RNA copying with a potentially primordial genetic alphabet
Fang, Z., Jia, X., Xing, Y., Szostak, J. W.
10.1101/2025.03.19.644114 — Posted: 2025-03-19
CTCF-RNA interactions orchestrate cell-specific chromatin loop organization
Lucero, K., Han, S., Huang, P.-Y., Qiu, X., Mazzoni, E. O., Reinberg, D.
10.1101/2025.03.19.643339 — Posted: 2025-03-19
RCVT: a diagnostic to quantify compositional biases among taxa for large phylogenomic studies
Steenwyk, J. L., Buida, T. J.
10.1101/2024.11.28.625917 — Posted: 2025-03-18
Discovery of neuronal cell types by pairing whole cell reconstructions with RNA expression profiles
Ferreira, T. A., Eddison, M., Copeland, M., Lay, M., Tenshaw, E., Weldon, M., Schauder, D., Olbris, D. J., Rokicki, K., Spruston, N., Tillberg, P. W., Chandrashekar, J., Korff, W., Dudman, J. T., The MouseLight Project Team
10.1101/2024.12.30.630829 — Posted: 2025-03-18
Genetic diversity and regulatory features of human-specific NOTCH2NL duplications
Real, T. D., Hebbar, P., Yoo, D., Antonacci, F., Pacar, I., Diekhans, M., Mikol, G. J., Popoola, O. G., Mallory, B., Vollger, M. R., Dishuck, P. C., Guitart, X., Rozanski, A. N., Munson, K. M., Hoekzema, K., Ranchalis, J. E., Neph, S. J., Sedeno-Cortes, A. E., Paten, B., Salama, S., Stergachis, A., Eichler, E. E.
10.1101/2025.03.14.643395 — Posted: 2025-03-17
Type IV pili-associated secretion of a biofilm matrix protein from Clostridium perfringens that forms intermolecular isopeptide bonds
Kivimaki, S. E., Dempsey, S., Tani, J. M., Camper, C., Hicklin, I. K., Blaby-Haas, C. E., Brown, A. M., Melville, S.
10.1101/2024.11.04.621531 — Posted: 2025-03-17
Nonequilibrium polysome dynamics promote chromosome segregation and its coupling to cell growth in Escherichia coli
Papagiannakis, A., Yu, Q., Govers, S. K., Lin, W.-H., Wingreen, N. S., Jacobs-Wagner, C.
10.1101/2024.10.08.617237 — Posted: 2025-03-15
A genome-scale drug discovery pipeline uncovers new therapeutic targets and a unique p97 allosteric binding site in Schistosoma mansoni
Stephens, D. R., Fung, H. Y. J., Han, Y., Liang, J., Chen, Z., Ready, J., Collins, J.
10.1101/2025.03.14.643303 — Posted: 2025-03-15
Design of solubly expressed miniaturized SMART MHCs
White, W. L., Bai, H., Kim, C. J., Jude, K. M., Sun, R., Guerrero, L., Han, X., Chen, X. T., Chaudhuri, A., Bonzanini, J. E., Sun, Y., Onwuka, A. E., Wang, N., Wang, C., Li, X., Goreshnik, I., Allen, A., Levine, P. M., Kueh, H. Y., Jewett, M. C., Sgourakis, N., Achour, A., Garcia, K. C., Baker, D.
10.1101/2025.03.14.643101 — Posted: 2025-03-14

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