Channel:  The Howard Hughes Medical Institute (HHMI)

2,194 Articles

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A regulatory region that controls Wnt gene expression following tissue injury is required for proper muscle regeneration
Logan, C. Y., Lim, X., Fish, M., Mizutani, M., Swain, B., Nusse, R.
10.1101/2025.10.01.679323 — Posted: 2025-10-03
De novo design of RNA and nucleoprotein complexes
Favor, A. H., Quijano, R., Chernova, E., Kubaney, A., Weidle, C., Esler, M. A., McHugh, L., Carr, A., Hsia, Y., Juergens, D., Carr, K. D., Kim, P. T., Politanska, Y., Sehgal, E., Kwon, P. S., Pecoraro, R. J., Glasscock, C., Borst, A. J., DiMaio, F., Stoddard, B. L., Baker, D.
10.1101/2025.10.01.679929 — Posted: 2025-10-02
Mapping Plasmodium transitions and interactions in the Anopheles female
Yan, Y., Verzier, L. H., Cheung, E., Appetecchia, F., March, S., Craven, A. R., Du, E., Probst, A. S., Rinvee, T. A., de Vries, L. E., Kauffman, J., Bhatia, S. N., Nelson, E., Singh, N., Peng, D., Shaw, W. R., Catteruccia, F.
10.1101/2024.11.12.623125 — Posted: 2025-10-02
Memory B cell Development in Response to mRNA SARS-CoV-2 and Nanoparticle Immunization in Mice
Wiatr, m., wang, z., Canis, M., Gazumyan, A., hernandez, B., Santos, G. S., Shawraz, S., lee, S., Bieniasz, P. D., Hatziioannou, T., Muecksch, F., Nussenzweig, M. C.
10.1101/2025.10.01.679787 — Posted: 2025-10-02
The specificity and structure of DNA crosslinking by the gut bacterial genotoxin colibactin
Carlson, E. S., Haslecker, R., Lecchi, C., Ramos, M. A. A., Vennelakanti, V., Honaker, L., Stornetta, A., Millan, E. S., Johnson, B. A., Kulik, H. J., Balbo, S., Villalta, P. W., D'Souza, V., Balskus, E. P.
10.1101/2025.05.26.655968 — Posted: 2025-10-01
Rational Design of Multiclade Coronavirus Spike Immunodominant Domain Nanoparticles Elicit Broad Antibody Responses
Dzuvor, C. K. O., Moak, S., McManus, L. R., Thomas, A., Dzordzorme, A. E., Kim, T., Joseph, J., Foley, V., Gordon, I. J., Novik, L., Holman, L. A., Dropulic, L. K., McNamara, R. P., Corbett-Helaire, K. S.
10.1101/2025.10.01.679649 — Posted: 2025-10-01
Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants
Dadonaite, B., Harari, S., Larsen, B. B., Kampman, L., Harteloo, A., Elias-Warren, A., Chu, H. Y., Bloom, J. D.
10.1101/2025.08.18.671001 — Posted: 2025-09-30
Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza hemagglutinin
Yu, T. C., Kikawa, C., Dadonaite, B., Loes, A. N., Englund, J. A., Bloom, J. D.
10.1101/2025.05.24.655919 — Posted: 2025-09-30
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
Goldman, O. V., DeFoe, A. E., Qi, Y., Jiao, Y., Weng, S.-C., Wick, B., Houri-Zeevi, L., Lakhiani, P., Morita, T., Razzauti, J., Rosas-Villegas, A., Tsitohay, Y. N., Walker, M., Hopkins, B. R., Mosquito Cell Atlas Consortium, , Joshua X D Ang, , Igor Antoshechkin, , Yu Cai, , Fangying Chen, , Yen-Chung Chen, , Julien Devilliers, , Linhan Dong, , Roberto Feuda, , Paolo Gabrieli, , Artyom Kopp, , Hyeogsun Kwon, , Hsing-Han Li, , Tzu-Chiao Lu, , Thalita Lucio, , Joao T Marques, , Marcus F Oliveira, , Roenick P Olmo, , Umberto Palatini, , Zeaan M Pithawala, , Julien Pompon, , Y
10.1101/2025.02.25.639765 — Posted: 2025-09-30
Brain Region-Specific Epigenomic Reorganization and Altered Cell States in Alzheimer's Disease
Wang, W., Berube, P., Yang, B., Castanon, R., Bartlett, A., Komandur, K., Nery, J. R., Barragan, C., Kenworthy, M., Valadon, C., Altshul, J., Petrella, A., Chan, D., Chen, C., Acerbo, A. S., Luo, J., Jain, M., Soma, E., Chen, H., Liem, M., Marrin, M., O'Connor, C., Zemke, N., Oakley, D. H., Ren, B., Hyman, B. T., Ecker, J. R.
10.1101/2025.09.29.678849 — Posted: 2025-09-30

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